Masked hypertension and neonatal outcome in high-risk pregnancies

2022 ◽  
Author(s):  
Martin R. Salazar ◽  
Walter G. Espeche ◽  
Carlos E. Leiva sisnieguez ◽  
Paola L. Juliano ◽  
María V. Vulcano ◽  
...  
Keyword(s):  
High Risk ◽  
Neonatal Outcome ◽  
Masked Hypertension

Does Placental Weight Affects Perinatal Outcome? A Prospective Case-control Study

2020 ◽  
Vol 16 (1) ◽  
pp. 52-59
Author(s):  
Naina Kumar ◽  
Himani Agarwal
Keyword(s):  
Birth Weight ◽  
High Risk ◽  
Perinatal Outcome ◽  
Case Control Study ◽  
Neonatal Outcome ◽  
Case Control ◽  
Placental Weight ◽  
Tertiary Center ◽  
Control Study ◽  
Prospective Case Control Study

Background: Placenta plays a very important role in the growth and development of fetus. Objective: To know the correlation between placental weight and perinatal outcome in term antenatal women. Methods: Present prospective case-control study was conducted in the rural tertiary center of Northern India over one year (January-December 2018) on 1,118 term (≥37-≤42 weeks) antenatal women with singleton pregnancy fulfilling inclusion criteria with 559 women with high-risk pregnancy as cases and 559 low-risk pregnant women as controls. Placental weight, birth weight was measured immediately after delivery and compared between the two groups along with gestation, parity, fetal gender, and neonatal outcome. Statistical analysis was done using SPSS 22 version. Results: Mean placental weight [481.98±67.83 gm vs. 499.47±59.59 gm (p=.000)] and birth weight [2.68±0.53 Kg vs. 2.88±0.4 Kg (p=.000)] was significantly lower in high risk as compared to lowrisk participants, whereas placental birth weight ratio was higher in high-risk cases [18.35±2.37 vs. 17.41±1.38 (p=.000)] respectively. Placental weight was positively correlated with birth weight and placental weight and birth weight increased with increasing gestation in both cases and controls. Male neonates had higher placental weight [492.74±68.24 gm vs. 488±58.8 gm (p=0.224)] and birth weight [2.81±0.5 Kg vs. 2.74±0.45 Kg (p=0.033)] as compared to females. Neonatal Intensive Care Unit admission was significantly associated with low placental and birth weight (p=.000). Conclusion: There is a significant correlation between placental weight, birth weight and neonatal outcome, hence placental weight can be used as an indirect indicator of intrauterine fetal growth.

Neonatal Outcome in High Risk Pregnancies

2015 ◽  
Vol 29 (4) ◽  
pp. 23-30
Author(s):  
Simranjeet Singh ◽  
Karuna Thapar ◽  
Madhu Nagpal
Keyword(s):  
High Risk ◽  
Neonatal Outcome

scholarly journals 1160 Effect of Cervical Colonization on Neonatal Outcome in High Risk Pregnancies: Results From a Tertiary Maternity Center in Turkey

2012 ◽  
Vol 97 (Suppl 2) ◽  
pp. A332-A333
Author(s):  
M. Oncel ◽  
S. Celen ◽  
G. Demirel ◽  
F. Canpolat ◽  
E. Calisici ◽  
...  
Keyword(s):  
High Risk ◽  
Neonatal Outcome

scholarly journals Impact of Intrapartum Cardiotocographic Monitoring on Neonatal Outcome in High Risk Pregnancies

2020 ◽  
Vol 7 (33) ◽  
pp. 1657-1661
Author(s):  
Kumudini Pradhan ◽  
Pranati Pradhan ◽  
Lipsa Patra
Keyword(s):  
High Risk ◽  
Neonatal Outcome

scholarly journals Using Latent Class Analysis to Identify Different Risk Patterns for Patients With Masked Hypertension

2021 ◽  
Vol 8 ◽  
Author(s):  
Ming Fu ◽  
Xiangming Hu ◽  
Shixin Yi ◽  
Shuo Sun ◽  
Ying Zhang ◽  
...  
Keyword(s):  
High Risk ◽  
Latent Class Analysis ◽  
Latent Class ◽  
Latent Class Model ◽  
Fasting Blood Glucose ◽  
Low Risk ◽  
Biological Information ◽  
Masked Hypertension ◽  
Class Analysis ◽  
The Impact

Background: There is controversy whether masked hypertension (MHT) requires additional intervention. The aim of this study is to evaluate whether MHT accompanied with high-risk metabolic syndrome (MetS), as the subphenotype, will have a different prognosis from low-risk MetS.Methods: We applied latent class analysis to identify subphenotypes of MHT, using the clinical and biological information collected from High-risk Cardiovascular Factor Screening and Chronic Disease Management Programme. We modeled the data, examined the relationship between subphenotypes and clinical outcomes, and further explored the impact of antihypertensive medication.Results: We included a total of 140 patients with MHT for analysis. The latent class model showed that the two-class (high/low-risk MetS) model was most suitable for MHT classification. The high-risk MetS subphenotype was characterized by larger waist circumference, lower HDL-C, higher fasting blood glucose and triglycerides, and prevalence of diabetes. After four years of follow-up, participants in subphenotype 1 had a higher non-major adverse cardiovascular event (MACE) survival probability than those in subphenotype 2 (P = 0.016). There was no interaction between different subphenotypes and the use of antihypertensive medications affecting the occurrence of MACE.Conclusions: We have identified two subphenotypes in MHT that have different metabolic characteristics and prognosis, which could give a clue to the importance of tracing the clinical correlation between MHT and metabolic risk factors. For patients with MHT and high-risk MetS, antihypertensive therapy may be insufficient.

scholarly journals Comparative efficacy of admission cardiotocography in high risk and low risk pregnancies in predicting neonatal outcome

2021 ◽  
Vol 10 (10) ◽  
pp. 3823
Author(s):  
Gurpreet Kaur Nandmer ◽  
Shivangi Jaiswal ◽  
Pooja Namdeo
Keyword(s):  
High Risk ◽  
Predictive Value ◽  
Neonatal Outcome ◽  
Low Risk ◽  
Comparative Efficacy ◽  
Risk Pregnancy ◽  
Risk Patients ◽  
Nicu Admission ◽  
Fetal Wellbeing ◽  
Sensitivity Specificity

Background: Admission cardiotocography (CTG) is a test of fetal wellbeing performed during labor. A normal CTG is for 20-30 minutes and ranges from 110-160 bpm with beat to beat variability, two accelerations and no decelerations with two contractions (as per NICE 2018 guidelines). To study comparative efficacy of admission CTG in predicting neonatal out in high risk, low risk and universally in all pregnancy.Methods: All high risk as well as low risk patients coming to labor room in labor were included in the study. CTG print was taken, and neonatal outcome as NICU admission were noted after taking written consent.Results: 189 cases were taken.138 were high risk cases, CTG was taken: 91were reassuring, 47were abnormal (non-reassuring +abnormal). In terms of NICU admission, 21 and 26 neonates were admitted. Out of 51 low risk cases, 33 had reassuring CTG, and18 had abnormal; 7and 6 was the number of NICU admission, respectively. When compared, highest sensitivity, specificity and positive predictive value of 55.31%, 77% and 55.3% was seen in high risk pregnancy, whereas negative predictive value (78.8%) was slightly higher in low risk cases.Conclusions: Admission CTG is a good predictor of neonatal outcome. Its predictive efficacy is more in high risk cases. It’s practicality in revealing poor neonatal outcome is more.

scholarly journals A study to evaluate pregnancy with maternal heart disease: a prospective observational study at a tertiary care centre in India

2021 ◽  
Vol 10 (4) ◽  
pp. 1637
Author(s):  
Khushboo Goel ◽  
Sanjaykumar G. Tambe
Keyword(s):  
Heart Disease ◽  
High Risk ◽  
Observational Study ◽  
Maternal Mortality ◽  
Prospective Observational Study ◽  
Neonatal Outcome ◽  
Risk Group ◽  
High Risk Group ◽  
Heart Disease In Pregnancy ◽  
In Pregnancy

Background: Prevalence of heart disease in pregnancy vary from 0.3-3.5%. Normal pregnancy is associated with physiological cardiovascular changes. These changes may unmask underlying cardiac disease in normal women and increase morbidity and mortality in women with heart disease. Heart disease in pregnancy is an important cause of maternal mortality in India. The aim of this study was to evaluate the maternal and neonatal outcome of pregnancy with heart disease.Methods: A prospective observational study was conducted at Sassoon General Hospital, Pune, India. 75 patients who fulfilled the inclusion criteria were studied. Maternal and neonatal outcome were analyzed.Results: Maternal heart disease was classified into congenital (36%) and acquired (64%). In acquired variety, rheumatic heart disease was most commonly seen. In congenital, ASD was most common. We divided the cases into two groups based on their NYHA status, low risk group had 74.67% patients and high risk group had 25.33% patients. The most common antenatal complication was PROM (41.3%). There was statistically significant association between ICU admission and high-risk group. The most common neonatal complications were IUGR and prematurity. Maternal mortality rate in the study group was 6.6%.Conclusions: The perinatal outcome of heart disease in pregnancy is more dependent on the severity of symptoms rather than the duration and type of heart disease. Multidisciplinary evaluation is necessary. Suboptimal optimization of the heart condition in the antenatal period and delayed referral were the major risk factor for maternal mortality. 

scholarly journals A study of bacteriological profile and outcome of babies born to mother with Premature rupture of membrane and its correlation with blood and gastric culture

2019 ◽  
Vol 6 (6) ◽  
pp. 2654
Author(s):  
Milind B. Kamble ◽  
Ramchandra Nagargoje ◽  
Sagar G. Chopde
Keyword(s):  
Birth Weight ◽  
High Risk ◽  
Neonatal Outcome ◽  
Tertiary Care ◽  
Specific Treatment ◽  
Active Management ◽  
Care Hospital ◽  
Membrane Rupture ◽  
Early Onset Sepsis ◽  
History Of

Background: PROM, a condition that occurs when fetal membranes are ruptured at least one hour before onset of labor. While PROM is observed in 10% of all pregnancies, 60-80% of PROM is observed in term and 20-40% in pregnancies less than 37th gestational week. PROM is the most significant reason for preterm labor. The three causes of neonatal death associated with PROM are prematurity, sepsis and pulmonary hypoplasia. Infants born with sepsis have a mortality rate four times higher than those without sepsis. Objective of the study was correlation of blood and gastric culture positive sepsis in PROM newborns. It helps to find out the incidence of PROM in our locality.Methods: This retrospective study enrolled 90 neonates born to healthy mothers with history of PROM more than 18 hours duration, admitted in SNCU/ward at a tertiary care hospital for six months duration from 1st January 2017 to 30 June 2017. Clinical profile of these Newborn with history of PROM was noted such as birth weight, gender, gestation, duration of membrane rupture, history of maternal fever. For all newborns with PROM, sepsis screen had been sent. The neonatal outcome was also recorded, and the data was collected and analyzed by using frequency and percentages.Results: Gram negative bacilli were the commonest cause of neonatal sepsis and male neonates were more prone to infection. PROM and low birth weight especially, ELBW and VLBW are the common high-risk factors for early onset sepsis. Most common organisms isolated in blood and gastric culture were Klebsiella and Staphylococcus aureus respectively.Conclusions: PROM is a high-risk obstetric condition. Active management is needed to enable delivery within 24 hours of PROM as it offers better neonatal outcome. Morbidity and mortality increase as the duration of PROM increases. This can be reduced by early diagnosis, specific treatment and strict infection control practices in neonatal units.

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