Intrauterine Surgery for Spinal Defects: What is the Role of Ultrasound?

Author(s):  
Renato AM de Sá ◽  
Fernando Peixoto-Filho ◽  
Luciana Cima

ABSTRACT Ultrasound imaging has led to the diagnosis of fetal anomalies that can affect many organ systems. Since the development of high-resolution real-time ultrasound, the possibility of surgical intervention before birth to correct or treat prenatally diagnosed abnormalities has been realized. Fetal surgery has become a new standard of care for the perinatal treatment of myelomeningocele for mothers and fetuses that meet the specific criteria. In this review, we will consider the role of ultrasound for open fetal surgery or minimally invasive fetal surgery approaches. How to cite this article Moreira de Sá RA, Peixoto-Filho F, Cima L. Intrauterine Surgery for Spinal Defects: What is the Role of Ultrasound? Donald School J Ultrasound Obstet Gynecol 2016;10(3):297-300.

Author(s):  
Toshiyuki Hata

ABSTRACT We present a series of images of different fetal intracranial, intrathoracic and intra-abdominal anomalies reconstructed using HDlive. It is a novel three-dimensional (3D) ultrasound modality that can provide the operator with naturally realistic features of any fetal anomalies. HDlive and its inversion mode are applied in several cases and two-dimensional (2D) sonographic images of different anomalies are also presented clearly to compare the advantages of HDlive in this article. This review focuses on the role of HDlive in the presence of such anomalies. HDlive should be a very useful aid in adjunct to other ultrasound modalities, specifically in cases that warrant detailed information. It can also be useful for the antenatal surveillance of anomalies, such as cystic lesions that may progress to complications. This innovative tool offers many promising advantages in clinical practice and future research on fetal anomalies. How to cite this article Cajusay-Velasco S, Hata T. HDlive in the Assessment of Fetal Intracranial, Intrathoracic and Intraabdominal Anomalies. Donald School J Ultrasound Obstet Gynecol 2014;8(4):362-375.


Author(s):  
Benjamin F. Trump ◽  
Irene K. Berezesky ◽  
Raymond T. Jones

The role of electron microscopy and associated techniques is assured in diagnostic pathology. At the present time, most of the progress has been made on tissues examined by transmission electron microscopy (TEM) and correlated with light microscopy (LM) and by cytochemistry using both plastic and paraffin-embedded materials. As mentioned elsewhere in this symposium, this has revolutionized many fields of pathology including diagnostic, anatomic and clinical pathology. It began with the kidney; however, it has now been extended to most other organ systems and to tumor diagnosis in general. The results of the past few years tend to indicate the future directions and needs of this expanding field. Now, in addition to routine EM, pathologists have access to the many newly developed methods and instruments mentioned below which should aid considerably not only in diagnostic pathology but in investigative pathology as well.


2004 ◽  
Vol 43 (06) ◽  
pp. 185-189 ◽  
Author(s):  
J. T. Kuikka

Summary Aim: Serotonin transporter (SERT) imaging can be used to study the role of regional abnormalities of neurotransmitter release in various mental disorders and to study the mechanism of action of therapeutic drugs or drugs’ abuse. We examine the quantitative accuracy and reproducibility that can be achieved with high-resolution SPECT of serotonergic neurotransmission. Method: Binding potential (BP) of 123I labeled tracer specific for midbrain SERT was assessed in 20 healthy persons. The effects of scatter, attenuation, partial volume, mis-registration and statistical noise were estimated using phantom and human studies. Results: Without any correction, BP was underestimated by 73%. The partial volume error was the major component in this underestimation whereas the most critical error for the reproducibility was misplacement of region of interest (ROI). Conclusion: The proper ROI registration, the use of the multiple head gamma camera with transmission based scatter correction introduce more relevant results. However, due to the small dimensions of the midbrain SERT structures and poor spatial resolution of SPECT, the improvement without the partial volume correction is not great enough to restore the estimate of BP to that of the true one.


Author(s):  
LM Sconfienza ◽  
F Lacelli ◽  
G Grillo ◽  
G Serafini ◽  
G Garlaschi ◽  
...  

1998 ◽  
Vol 38 (6) ◽  
pp. 1027
Author(s):  
Kyoung Suk Kim ◽  
Young Tong Kim ◽  
Eun Joo Kwon ◽  
Choung Sik Choi ◽  
Han Heag Im ◽  
...  

Author(s):  
Miriam Michel ◽  
Manuela Zlamy ◽  
Andreas Entenmann ◽  
Karin Pichler ◽  
Sabine Scholl-Bürgi ◽  
...  

: In patients having undergone the Fontan operation, besides the well discussed changes in the cardiac, pulmonary and gastrointestinal system, alterations of further organ systems including the hematologic, immunologic, endocrinological and metabolic are reported. As a medical adjunct to Fontan surgery, the systematic study of the central role of the liver as a metabolizing and synthesizing organ should allow for a better understanding of the pathomechanism underlying the typical problems in Fontan patients, and in this context, the profiling of endocrinological and metabolic patterns might offer a tool for the optimization of Fontan follow-up, targeted monitoring and specific adjunct treatment.


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
L Tulecki ◽  
M Czajkowski ◽  
S Targonska ◽  
K Tomkow ◽  
D Nowosielecka ◽  
...  

Abstract Background The guidelines suggest close co-operation between TLE operating team and cardiac surgery and its key role in the management of life-threatening complications remains unquestionable. But the role of cardiac surgeon seems to be much more extended. Purpose We have analysed the role of cardiac surgery in treatment of patients undergoing TLE procedures. Methods Using standard non-powered mechanical systems we have extracted ingrown PM/ICD leads from 3207 pts (38,7% female, average age 65,7-y) during the last 14 years. Non-infectious TLE indications were in 66,4% of patients. 46% had PM DDD system, 19% PM SSI, 22% ICD, 9% CRT, 4% other systems. In 12% of patients abandoned leads were found. 8% of patients had one lead, 54% - two, 15% - three and 4% - 4–6 leads in the heart. An average dwell time of all leads was 91,5 mth. The lead entry side was left in 96% of patients, right in 3% and both – 4%. Results Procedural success 96,1%, clinical success - 97,8%, procedure-related death 0,2%. Major complications appeared in 1,9% (cardiac tamponade 1,2%, haemothorax 0,2%, tricuspid valve damage 0,3%, stroke, pulmonary embolism <1%). Conclusions Rescue cardiac surgery (for severe haemorrhagic complications) is still the most frequent reason of surgical intervention (1,1%). The second area of co-operation includes supplementary cardiac surgery after (incomplete) TLE (0,8%). The third one is connected with reconstruction or replacement of tricuspid valve, which can be affected by ingrown lead or damaged during TLE procedure (0,5%). Implantation of the complete epicardial system during any surgical intervention (rescue or delayed) should be considered as a supplementation of the operation (0,65%). Some of patients after TLE need implantation of epicardial leads for permanent epicardial pacing (0,6%) and some only left ventricular lead to rebuild permanent cardiac resynchronisation (0,5%). The single experience of large TLE centre indicates the necessity of close co-operation with cardiac surgeon, whose role seems to be more comprehensive than a surgical stand-by itself. Table 1 Funding Acknowledgement Type of funding source: None


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