Juvenile Ossifying Fibroma in a Juvenile Diabetic: A Case Report with Surgical Management

2010 ◽  
Vol 1 (1) ◽  
pp. 59-64
Author(s):  
Jagadish Hosmani ◽  
Sujata M Byahatti ◽  
Ranganath Nayak ◽  
Ramakant Nayak ◽  
Bhushan Jayade
Keyword(s):  
High Recurrence Rate ◽  
Ossifying Fibroma ◽  
Histopathological Diagnosis ◽  
Massive Growth ◽  
Juvenile Ossifying Fibroma ◽  
Histological Variants ◽  
Long Term Follow Up ◽  
Juvenile Diabetic

ABSTRACT Juvenile ossifying fibroma (JOF) is a highly aggressive uncommon fibro-osseous lesion occurring in the facial bones. Two histological variants of JOF, i.e. trabecular and psammomatoid have been reported. Here we present a case of a 20-year-old juvenile diabetic patient with massive growth on her left side of the jaw which was diagnosed as juvenile ossifying fibroma. This huge aggressive mass in the left side of the mandible had lead to complete lingual tilting of molars and premolars. After clinical and radiological examination, a biopsy led to the histopathological diagnosis of mixed variant of juvenile ossifying fibroma. The required surgical treatment (hemimandibulectomy) was undertaken under GA. The aggressive local behavior and high recurrence rate of JOF emphasizes the need for an early diagnosis, and appropriate radical treatment with long-term follow-up. One such case is reviewed and discussed in detail in the following article.

scholarly journals Juvenile Aggressive Trabecular Ossifying Fibroma of Mandible: A Rare Case Report

2016 ◽  
Vol 6 (1) ◽  
pp. 45-51
Author(s):  
Deepa Das Achath ◽  
Abhishek Sanjay Ghule ◽  
Preeti Kanchan-Talreja ◽  
Sunanda Bhatnagar
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Histological Analysis ◽  
High Recurrence Rate ◽  
Ossifying Fibroma ◽  
Appropriate Treatment ◽  
Juvenile Ossifying Fibroma ◽  
Rare Case Report

ABSTRACT Fibroosseous lesions of the jaws, including juvenile ossifying fibroma (JOF), pose diagnostic and therapeutic difficulties due to their clinical, radiological, and histological variability. There are two histological varieties of it, one as psammomatoid type and second as trebacular type; here, we present a trebacular type, which is a rare variety. After the clinical examination, radiological and histological analysis, it was diagnosed as juvenile trebacular ossifying fibroma. Although JOF is an uncommon clinical entity, its aggressive local behavior and high recurrence rate means that it is important to make an early diagnosis, apply the appropriate treatment, and, especially, follow-up the patient over the long term. How to cite this article Ghule AS, Achath DD, Kanchan- Talreja P, Bhatnagar S. Juvenile Aggressive Trabecular Ossifying Fibroma of Mandible: A Rare Case Report. J Contemp Dent 2016;6(1):45-51.

scholarly journals Synchronous Juvenile ossifying Fibroma in maxilla and mandible- A case report

2014 ◽  
Vol 4 (2) ◽  
pp. 54-57
Author(s):  
B Shrestha ◽  
S Subedi ◽  
S Pandey
Keyword(s):  
Histopathological Examination ◽  
Ossifying Fibroma ◽  
Medical College ◽  
Appropriate Treatment ◽  
Juvenile Ossifying Fibroma ◽  
Long Term Follow Up ◽  
Maxilla And Mandible ◽  
The Right

Juvenile ossifying fibroma (JOF), one of the fibroosseous lesions is an uncommon clinical entity and involving both jaw is even rarer. Here, we present the case of a 15-year-old female patient with synchronous occurrence of JOF in the right sided maxilla and in the periapical area of mandibular right premolar molar region. After the clinical, radiographical and histopathological examination, the surgical treatment was carried out and the patient was kept under long term follow up. Owning to its aggressive local behaviour and high recurrence, early diagnosis, appropriate treatment and long term regular follow up are of prime importance. DOI: http://dx.doi.org/10.3126/jcmc.v4i2.10867 Journal of Chitwan Medical College 2014; 4(2): 54-57

Salvage Surgical Resection After Linac-based Stereotactic Radiosurgery and Radiotherapy for Newly Diagnosed Brain Metastasis

2021 ◽  
Author(s):  
Ryosuke Matsuda ◽  
Takayuki Morimoto ◽  
Tetsuro Tamamoto ◽  
Nobuyoshi Inooka ◽  
Tomoko Ochi ◽  
...  
Keyword(s):  
Brain Metastasis ◽  
Survival Time ◽  
Stereotactic Radiosurgery ◽  
Surgical Resection ◽  
Cyst Formation ◽  
Histopathological Diagnosis ◽  
Newly Diagnosed ◽  
Long Term Follow Up

Abstract Purpose: This study aimed to assess the clinical outcomes of salvage surgical resection (SSR) after stereotactic radiosurgery and fractionated stereotactic radiotherapy (SRS/fSRT) for brain metastasis.Methods: Between November 2009 and December 2018, we treated 427 consecutive patients with 919 lesions with SRS/fSRT for newly diagnosed brain metastasis at our hospital. During the follow-up period, we treated 19 consecutive patients who underwent 21 SSRs for recurrence, radiation necrosis (RN), and cyst formation after SRS/fSRT for newly diagnosed brain metastasis. Two patients underwent multiple surgical resections. Brain metastasis originated from the lung (n=15, 78.9%), breast (n=3, 15.7%), and colon (n=1, 5.2%). Results: The median time from initial SRS/fSRT to SSR was 14 months (range: 2–96 months). The median follow-up after SSR was 15 months (range: 2–76 months). The range of tumor volume at initial SRS/SRT was 0.121–21.459 cm3 (median: 2.188 cm3). Histopathological diagnosis after SSR was recurrence, RN and cyst formation in 13 and 6 cases, respectively. The median survival time from SSR and from initial SRS/SRT was 17 months and 74 months, respectively. The cases with recurrence had a significantly shorter survival time than those without recurrence (p=0.0453).Conclusion: The patients treated with SRS/fSRT for brain metastasis need long-term follow-up. SSR is a safe and effective treatment for the recurrence, RN, and cyst formation after SRS/fSRT for brain metastasis.

Management and outcome of acute and recurrent pericarditis during pregnancy

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
D Lotan ◽  
Y Wasserstrum ◽  
E Itelman ◽  
M Nir-Simchen ◽  
M Arad ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Q Fever ◽  
Treatment Options ◽  
Subsequent Treatment ◽  
High Recurrence Rate ◽  
Recurrent Pericarditis ◽  
Long Term Follow Up

Abstract Background Pericarditis in pregnancy is uncommon. Treatment options, including NSAIDs and long term gluco-corticosteroids (CS) have extensive side-effects, while data on the use of Colchicine in pregnant women who suffer from pericarditis is limited. Objective To evaluate the management and outcome of active pericarditis during pregnancy in both acute (AP) and recurrent pericarditis (RP) patients. Methods and results Twelve pregnant women (14 pregnancies) with active pericarditis were followed prospectively in our cardiology-pregnancy clinic; 6 with AP and 8 with RP. Etiology: 11 idiopathic, 2 post-pericardiotomy syndrome and 1 Q fever. Maternal age on presentation was 27±4y vs. 33±3y in RP vs AP respectively. Average gestational age upon diagnosis was lower in RP than in AP (18 weeks, range 6–30 vs 26 weeks, range 5–35). In the RP group, 7/8 women (87%) were treated with CS compared with 2/6 women (33%) in the AP group; 3 women in RP group (37%) failed to respond to subsequent treatment with azathioprine and 1 patient was treated successfully with Anakinra. Colchicine was prescribed in 13/14 (93%) of pregnancies, average colchicine exposure during pregnancy was 25±15 weeks. Recurrence during pregnancy: 6/8 (75%) of RP; 2/6 (33%) of the AP, all of them on CS. All pregnancies culminated in a live birth with a mean gestational age on delivery of 37±1.4 weeks. Average birthweight was 3267±507 grams. There were no fetal anomalies or developmental delays after a mean follow-up of 2.7 years. All newborns and maternal outcomes were normal. On long term follow-up after delivery RP patients treated with colchicine developed less recurrences. Conclusion Active pericarditis is associated with a high recurrence rate during pregnancy despite treatment with CS. Colchicine use in pregnant women with active pericarditis appears to be safe. Funding Acknowledgement Type of funding source: None

Odontogenic Fibromyxoma in a Cat: First Confirmed Case in This Species

2017 ◽  
Vol 34 (1) ◽  
pp. 18-29
Author(s):  
Kristin I. Scott ◽  
Colin E. Harvey ◽  
James G. Anthony ◽  
Roy Pool
Keyword(s):  
Literature Review ◽  
Clinical Presentation ◽  
Case Reports ◽  
Companion Animals ◽  
Histopathological Diagnosis ◽  
Extensive Literature ◽  
En Bloc ◽  
Long Term Follow Up

An inflammatory gingival mass surrounding resorbing teeth was diagnosed via biopsy in a 9-year-old domestic shorthair cat. A dorsal rim excision was performed to remove the entire mass with associated teeth and bone. Histopathological diagnosis of the en bloc tissue revealed an odontogenic fibromyxoma. Extensive literature review revealed few case reports of companion animals with this neoplasm, and none in a feline patient. This report documents the clinical presentation, diagnostic differentials, surgical therapy, and long-term follow-up of an odontogenic fibromyxoma in a cat.

scholarly journals Juvenile psammomatoid ossifying fibroma of maxilla: A case report

2022 ◽  
Vol 7 (4) ◽  
pp. 247-249
Author(s):  
Vasvani M Dimple ◽  
Irom Urmila ◽  
Tuladhar Alisha ◽  
Neeraj ◽  
Chug Ashi
Keyword(s):  
Recurrence Rate ◽  
High Recurrence Rate ◽  
Ossifying Fibroma ◽  
Complete Excision ◽  
Juvenile Ossifying Fibroma ◽  
Histological Variant ◽  
Oral Approach ◽  
Psammomatoid Ossifying Fibroma ◽  
Very High

Juvenile psammomatoid ossifying fibroma is histological variant of juvenile ossifying fibroma, a fibro-osseous tumor of craniofacial bones with benign but potentially aggressive nature. Complete excision of tumor is essential as it is associated with very high recurrence rate. We have reported here a case of juvenile ossifying fibroma- a psammomatoid variety present in right maxilla in a 13-year old male child. Complete excision of tumor was done through intra-oral approach with the 2.5 years of follow up shows no recurrence.Juvenile psammomatoid ossifying fibroma is fibro-osseous tumor of craniofacial bones with benign but potentially aggressive nature. Complete excision of tumor is essential as it is associated with very high recurrence rate.

scholarly journals Multiple Odontogenic Keratocysts in a Non-syndromic Young Patient: An Unusual Case Report

2021 ◽  
Vol 9 (01) ◽  
pp. 87-90
Author(s):  
Ravish Mishra ◽  
Laxmi Kandel ◽  
Deepak Yadav ◽  
Shashank Tripathi ◽  
Bijay Karki ◽  
...  
Keyword(s):  
High Recurrence Rate ◽  
Jaw Cysts ◽  
Dental Lamina ◽  
Odontogenic Keratocysts ◽  
Goltz Syndrome ◽  
Long Term Follow Up ◽  
Intraosseous Lesion ◽  
Unusual Case Report

Odontogenic keratocyst (OKC) is a benign intraosseous lesion with invasive and aggressive behavior. It comprises approximately 2-21.8% of all jaw cysts. Odontogenic keratocysts (OKCs) are believed to arise from remnants of the dental lamina most common site in the molar ramus area. OKCs have a specific histopathologic appearance and are found to be locally aggressive and have a high recurrence rate, thus requires close long-term follow-up. OKCs are one component of the Gorlin-Goltz syndrome and all patients with multiple OKCs should be evaluated for this syndrome. In this paper, we present a case of a 13-year old non-syndromic female patient with multiple OKCs located at symphysis and bilateral mandibular angle region who was treated surgically with no obvious post-operative complications during follow-up period.

Rehabilitation After Hamstring-Strain Injury Emphasizing Eccentric Strengthening at Long Muscle Lengths: Results of Long-Term Follow-Up

2017 ◽  
Vol 26 (2) ◽  
pp. 131-140 ◽  
Author(s):  
Timothy F. Tyler ◽  
Brandon M. Schmitt ◽  
Stephen J. Nicholas ◽  
Malachy P. McHugh
Keyword(s):  
Recurrence Rate ◽  
Outcome Measures ◽  
Sports Medicine ◽  
Return To Sport ◽  
High Recurrence Rate ◽  
Hamstring Strain ◽  
Long Term Follow Up ◽  
Recurrent Injuries

Context:Hamstring-strain injuries have a high recurrence rate.Objective:To determine if a protocol emphasizing eccentric strength training with the hamstrings in a lengthened position resulted in a low recurrence rate.Design:Longitudinal cohort study.Setting:Sports-medicine physical therapy clinic.Participants:Fifty athletes with hamstring-strain injury (age 36 ± 16 y; 30 men, 20 women; 3 G1, 43 G2, 4 G3; 25 recurrent injuries) followed a 3-phase rehabilitation protocol emphasizing eccentric strengthening with the hamstrings in a lengthened position.Main Outcome Measures:Injury recurrence; isometric hamstring strength at 80°, 60°, 40°, and 20° knee flexion in sitting with the thigh flexed to 40° above the horizontal and the seat back at 90° to the horizontal (strength tested before return to sport).Results:Four of the 50 athletes sustained reinjuries between 3 and 12 mo after return to sport (8% recurrence rate). The other 42 athletes had not sustained a reinjury at an average of 24 ± 12 mo after return to sport. Eight noncompliant athletes did not complete the rehabilitation and returned to sport before initiating eccentric strengthening in the lengthened state. All 4 reinjuries occurred in these noncompliant athletes. At time of return to sport, compliant athletes had full restoration of strength while noncompliant athletes had significant hamstring weakness, which was progressively worse at longer muscle lengths (compliance × side × angle P = .006; involved vs noninvolved at 20°, compliant 7% stronger, noncompliant 43% weaker).Conclusion:Compliance with rehabilitation emphasizing eccentric strengthening with the hamstrings in a lengthened position resulted in no reinjuries.

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