scholarly journals Low Grade Central Mucoepidermoid Carcinoma

2015 ◽  
Vol 5 (1) ◽  
pp. 31-34
Author(s):  
Kartik Poonja ◽  
Janaki Subramanian Iyer ◽  
Leela Poonja

ABSTRACT Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor, comprising about 15% of all salivary gland tumors and 30% of all salivary malignancies. Most of the MEC arise in the parotid gland. Rarely, it originates in the mandible and maxilla as an intraosseous variant, referred to as ‘central mucoepidermoid carcinoma’ or ‘intraosseous mucoepidermoid carcinoma’. Central mucoepidermoid carcinomas (CMECs) are extremely rare, but well-known entity, comprising 2 to 3% of all MECs reported. Histopathologically, this malignant neoplasm is characterized by mucous, intermediate and epidermoid cells. In this report, we present a case of a male patient diagnosed as low grade CMEC. How to cite this article Iyer JS, Poonja K, Pathak J, Patel S, Poonja L. Low Grade Central Mucoepidermoid Carcinoma. J Contemp Dent 2015;5(1):31-34.

2019 ◽  
Vol 15 (3) ◽  
pp. 202-205
Author(s):  
Rajina Sahi ◽  
Dilip Karmacharya ◽  
Dej Kumar Gautam ◽  
Anil Bikram Karki ◽  
Amar Shrestha

Background: Salivary gland tumors represent a different variety of histological types. The definite diagnosis of type of salivary gland tumor is required for proper treatment planning. The aim of this study was to evaluate the pattern of salivary gland malignancy in B.P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan. Methods: This cross-sectional study was carried out in patients of malignant salivary gland tumor registered in B.P. Koirala Memorial Cancer hospital retrospectively from September 2009 to August 2012. Results: Parotid gland was the most common sites for malignant salivary gland tumor (80%) followed by submandibular gland (20%). Mucoepidermoid carcinoma is the most common malignant salivary gland tumor of parotid gland and Adenoid cystic carcinoma was the most common malignant tumor of submandibu-lar gland. Male: Female ratio was 1.5:1 with age range from 12 years to 71 years. Common age group for malignant salivary gland tumor was from 50 to 60 years. Conclusions: Parotid was the most common site whereas Mucoepidermoid carcinoma was the most common malignant tumor of major salivary gland.


1976 ◽  
Vol 102 (11) ◽  
pp. 699 ◽  
Author(s):  
Dale H. Rice ◽  
John G. Batsakis ◽  
Kenneth D. McClatchey

2016 ◽  
Vol 15 (1) ◽  
pp. 95-98
Author(s):  
Afroza Khanam ◽  
Gulshan Akhter ◽  
Md. Abdur Rahman

Background: Salivary gland tumors are rare, generally benign and affect both major and minor salivary glands.Objective: To find out the pattern of distribution of different benign and malignant salivary gland epithelial tumors and their relation to age and sex in a tertiary care center in Bangladesh.Methodology: This is a retrospective study. Details of epithelial salivary gland tumors were obtained from department of ENT, National institute of cancer & research hospital (NICRH), Dhaka, Bangladesh from the period January 2009 to December 2012 (3 years).Result: A total number of 261 cases presenting with both benign and malignant salivary gland tumors were analyzed according to gender, age and histopathological findings. There were 130 (49.84%) males and 131 (50.19%) females with the male female ration of 1: 0.99. Age of study population ranged from 10 to 70 years with the mean age 40.78. Percentage of benign salivary gland tumors was 73.94% and malignant salivary gland tumor 26.05%. Among major salivary gland tumors, no sublingual tumors were found and parotid gland tumors were the commonest. Whereas, among minor salivary gland tumors palatal minor salivary tumors were common.Conclusion: Parotid gland was the most common site of origin of both benign and malignant salivary gland tumors. Histopathologically, pleomorphic adenoma was the most common benign salivary gland tumor and mucoepidermoid carcinoma was the most frequent malignant neoplasm. Adenoid cystic carcinoma was common minor salivary gland tumor.Bangladesh Journal of Medical Science Vol.15(1) 2016 p.90-94


2018 ◽  
Vol 6 ◽  
pp. 2050313X1881871 ◽  
Author(s):  
Nicole Diaz-Segarra ◽  
Lauren K Young ◽  
Kristin Levin ◽  
William Rafferty ◽  
Joshua Brody ◽  
...  

Warthin tumor is the second most common benign salivary gland tumor that classically arises in the parotid gland. It can be synchronous, metachronous, multifocal, bilateral, or unilateral, which complicates diagnosis and management. Rare cases of Warthin tumor of the minor salivary gland are described, but no cases of unilateral, synchronous Warthin tumor involving the parotid and minor salivary gland have been reported. We present a case of Warthin tumor arising from a minor salivary gland in the left oropharynx of a 71-year-old male with a previous history of left parotid Warthin tumor, later determined to be synchronous.


2019 ◽  
Vol 2 (2) ◽  
pp. 234-238
Author(s):  
Niraj Nepal ◽  
Prabesh Kumar Choudhary ◽  
Manish Kumar Das ◽  
Meenakshi Basnet ◽  
Sagar Paudel

Introduction: Salivary gland tumors are a heterogeneous group of neoplasms that are relatively rare but represent a wide variety of both benign and malignant histopathologic subtypes. The aim of this study was to find out the histopathological distribution of primary salivary gland tumors and correlate fine needle aspiration cytology reports with histological findings.Materials and Methods: A total of 83 patients attending the otorhinolaryngology department with salivary gland tumors were enrolled in our study. The histopathological findings were reported and correlated with cytological findings.Results: The mean age of the patient with salivary tumors was 43.11 ± 13.02 years. Out of 83 cases, 3 (3.6%) patients were diagnosed as inflammatory lesions, 64 (77.1%) patients had benign salivary gland tumors and 16 (19.3%) of patients had malignant salivary glands tumors in histopathology. The sensitivity and specificity of FNAC in this series for detecting salivary gland malignancy were 68.8% and 98.5% respectively with an overall diagnostic accuracy of 92.8%. The most common salivary gland tumor was found to be pleomorphic adenoma (56.6%) and the most common malignant salivary gland tumor was found to be mucoepidermoid carcinoma (19.3%). The comparison of the incidence of salivary gland tumors in various age groups showed a statisticallysignificant difference (p=0.009).  Conclusions: Benign salivary tumors are more common than malignant tumors with the most common occurrence in parotid glands. Pleomorphic adenoma is the most common benign tumor whereas; mucoepidermoid carcinoma is the most common malignant tumor in patients visiting Nobel medical college.


PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0143009 ◽  
Author(s):  
Xiangbing Wu ◽  
Jun Yu ◽  
Guilin Gao ◽  
Xin Wang ◽  
Yang Liu ◽  
...  

1980 ◽  
Vol 88 (4) ◽  
pp. 391-396 ◽  
Author(s):  
Stephen J. Wetmore ◽  
Kang Fan

A case of a large (5.5 cm), multilobulated, mucosa-covered, minor salivary gland tumor of the base of the tongue that displayed morphologic features of both a mucoepidermoid carcinoma and an acinous cell tumor is described. Generally, each of these salivary gland tumors occurs only rarely at this site. A tumor with both these elements has not previously been reported.


2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Krysten Clark

Background: A pleomorphic adenoma is the most common salivary gland neoplasm in both children and adults. Pleomorphic adenomas are derived from ductal and myoepithelial cells and are most commonly found in the superficial lobe of the parotid gland. The purpose of this article is to discuss the genes involved in pleomorphic adenomas and the possible autosomal dominant mode of inheritance. Case Description: The first patient was a white male who was diagnosed with carcinoma ex pleomorphic adenoma, a highly aggressive tumor, at the age of 57. He had an undiagnosed pleomorphic adenoma for approximately 15 years prior. The tumor was excised and the patient underwent radiation in the location of his parotid gland for 4 years until he deceased. The second patient is a white female, his daughter, who was diagnosed with a benign pleomorphic adenoma at the age of 46. Her salivary gland tumor was excised and normal follow up appointments occurred. Practical Implications: Pleomorphic adenomas most commonly affect the parotid gland, the largest of the three major salivary gland tumors. Occurrence and excision of this salivary gland tumor will cause a decrease in the secretion of saliva, leading to a dry mouth and an increased risk of caries.


2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Yan Zhou ◽  
Ernesto Martinez Duarte ◽  
David J. Eleff ◽  
Laura J. Tafe ◽  
Jason M. Leibowitz ◽  
...  

Background. The presence of two or more tumor entities growing in adjacent locations within the salivary gland is very rare, and pathologic studies on such lesions are limited, particularly those with molecular information. Since the clinical history and imaging studies are usually nonspecific, accurate diagnosis and clinical management largely depend on a thorough histological examination. Methods and Results. We describe a 71-year-old man with an unusual case of hybrid salivary gland tumor composed of mucoepidermoid carcinoma and basal cell adenoma. Molecular analysis revealed differing driver genetic alterations in each component. Conclusions. Hybrid salivary gland tumors are rare, and their pathogenesis is controversial. The combination of mucoepidermoid carcinoma and basal cell adenoma has not been previously described. While malignant transformation of adenoma to carcinoma seems plausible, gene sequencing was more suggestive of their independent derivation. Key to appropriate surgical management is identifying the more aggressive component, ideally at the time of intraoperative consultation.


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