scholarly journals Enhancing Osteoblast Response and Biointegration in vivo: Grown Zirconium Oxide Nanotube Bundles on Zirconium Surgical Screw

2021 ◽  
Vol 13 (3) ◽  
Author(s):  
Asmaa Hadi Mohammed ◽  
Marwa Abdul Muhsien Hassan
Keyword(s):  
Zirconium Oxide ◽  
Nanotube Bundles

Histologic and Ultrastructural Analysis in a Case of Massive Failure of Zirconia Ball Head

2002 ◽  
Vol 12 (4) ◽  
pp. 388-393
Author(s):  
G. Maccauro ◽  
L. Petrella ◽  
L. Proietti ◽  
V. De Santis ◽  
C. Piconi
Keyword(s):  
Zirconium Oxide ◽  
Internal Surface ◽  
Giant Cells ◽  
Sem Analysis ◽  
Ultrastructural Analysis ◽  
Periprosthetic Tissue ◽  
X Ray ◽  
Internal Part ◽  
Scanning Electron

The in vivo histological and ultrastructural analysis of periprosthetic tissue collected at time of revision surgery for failure of a 28 mm yttria-tetragonal zirconium oxide polycrystal (YTZP) ball head, 2 years after implantation is reported. Histologic analysis showed Zirconia particles, rounded to polygonal ranging from 2μm to more than 10μm intra or extra cellular in a stroma without vessels with few giant cells. Scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDAX) showed the different shape from rounded to polygonal of Zirconia. SEM analysis of the internal part of Zirconia ball head showed the presence of different fracture lines especially in the internal surface

Bacterial Adhesion on Commercially Pure Titanium and Zirconium Oxide Disks: An In Vivo Human Study

2004 ◽  
Vol 75 (2) ◽  
pp. 292-296 ◽  
Author(s):  
Antonio Scarano ◽  
Maurizio Piattelli ◽  
Sergio Caputi ◽  
Gian Antonio Favero ◽  
Adriano Piattelli
Keyword(s):  
Bacterial Adhesion ◽  
Zirconium Oxide ◽  
Human Study ◽  
Pure Titanium ◽  
Commercially Pure Titanium ◽  
Commercially Pure

scholarly journals Wear of Glass-ceramic-veneered Zirconia Posterior FPDS After 10 Years

2020 ◽  
Author(s):  
Ragai Edward Matta ◽  
Constantin Motel ◽  
Elena Kirchner ◽  
Simon Stelzer ◽  
Werner Adler ◽  
...  
Keyword(s):  
Glass Ceramic ◽  
Zirconium Oxide ◽  
Multiple Testing ◽  
Clinical Success ◽  
Three Dimensional ◽  
Rank Test ◽  
Minimal Distance ◽  
Significance Level ◽  
Volume Decrease

Abstract BackgroundThe abrasion behavior of various ceramics is rarely investigated, though it is relevant for the clinical success of such restorations. The aim of this in vivo study was to evaluate the wear of glass-ceramic-veneered zirconium oxide frameworks over a period of 10 years.MethodsThe abrasive behavior of the restorations was examined in a total of 15 patients after a period of 3, 5, and 10 years using plaster models, which were then subjected to a scanning process on the Atos II industrial scanner and digitized for three-dimensional evaluation of the abrasion by the corresponding software (ATOS Professional 7.6). The individual post-examination models were compared to the baseline model and deviations calculated in the sense of the largest, punctual loss of material in millimeters ("minimal distance"), the average abrasion in millimeters ("mean distance"), and the volume decrease in cubic millimeters ("integrated distance"). Statistical analyses were performed using the Wilcoxon sign rank test or mixed regression models. Multiple testing was considered by Benjamini-Hochberg correction. The significance level was set at 0.05.ResultsWe found steadily increasing wear of the ceramic. The average volume decrease was significant (P < 0.001) at 3 years and 10 years (-3.25 mm3 and − 8.11 mm3, respectively).ConclusionsDespite the increasing wear of the glass-ceramic-veneered zirconium oxide frameworks in this study, the use of this class of materials can be regarded as clinically acceptable.This study is registered in DRKS - German Clinical Trials Registerwith the Register number 00021743

Zirconium oxide coating improves implant osseointegration in vivo

2008 ◽  
Vol 24 (3) ◽  
pp. 357-361 ◽  
Author(s):  
V SOLLAZZO ◽  
F PEZZETTI ◽  
A SCARANO ◽  
A PIATTELLI ◽  
C BIGNOZZI ◽  
...  
Keyword(s):  
Zirconium Oxide ◽  
Oxide Coating

Formulation Development and Characterization of Rilpivirine Nanosuspension for Improved Solubility by Nanomilling

2019 ◽  
Vol 4 (2) ◽  
pp. 130-137
Author(s):  
Satya Sankar Sahoo ◽  
Chandu Babu Rao
Keyword(s):  
Zirconium Oxide ◽  
Particle Diameter ◽  
In Vivo Studies ◽  
X Ray Diffraction ◽  
Formulation Development ◽  
Flow Properties ◽  
X Ray ◽  
Sedimentation Volume

The objective of this study was to formulate and optimize a stable rilpivirine nanosuspension. In the present study, yttrium stabilized zirconium oxide beads being used as the milling media in nanomilling process. The lyophilized nanocrystals were being characterized by particle size distribution (PSD), polydispersity index (PDI), X-ray diffraction (XRD) and FTIR (Fourier transform infrared spectroscopy). Optimized nanosuspension has mean particle diameter of 266 nm, PDI of 0.158, zeta potential of 22.1 mV and spherical in shape with surface oriented stabilizer molecules. Flow properties like sedimentation volume, poura-bility with the F value of 0.94 and also the redispersability even after 4 weeks of storage was found to be satisfactory for the optimized nano-suspension. Many folds increase in solubility and rate of drug release observed, The lyophilized nanocrystals retains its crystallinity after nanomilling, stable chemically with high drug content, therefore, the developed nanosuspension would be an alternative better formulation than its conventional formulation to address its bioavailability issue. However, this should be further confirmed by appropriate techniques in vivo studies.

scholarly journals Early Soft Tissue Response to Zirconium Oxide and Titanium Healing Abutments in Vivo: A Dog Study

2021 ◽  
Author(s):  
Min Wang ◽  
Shuang Zhang ◽  
Longjie Chen ◽  
Haixiao Zou ◽  
Yining Wang ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Zirconium Oxide ◽  
Soft Tissues ◽  
Inflammatory Cells ◽  
Tissue Response ◽  
Clinical Index ◽  
Tissue Responses ◽  
Soft Tissue Response ◽  
Crevicular Fluid

Abstract Background: This study aimed to investigate clinical characteristics and early soft tissues response to zirconium oxide (Zr) and titanium (Ti) abutments in dogs. Methods: Eight implants-four at each hemi-mandible were inserted after bilateral mandibular third and fourth premolars and first molars extraction. Two Zr and two Ti healing abutments were connected in each unilateral mandible 8 weeks later. The ligation method was used to make peri-implant mucositis model. The twenty-four abutments were divided into four groups, Zr and Ti healing abutments with ligation (ZrL, TiL) and non-ligation (ZrN, TiN) groups. Clinical index, peri-implant crevicular fluid (PICF) and inflammatory cytokines (TNF-α and IL-1β), soft tissue responses were tested. Two-way analysis of variance was used to analyze the data. Results: The results showed that the clinical index were similar around Zr and Ti healing abutments. PICF in ZrL and TiL groups were significantly higher than those in ZrN and TiN groups. Immunohistochemistry demonstrated inflammatory cells were non-significant differences. Conclusion: These data indicate soft tissue responses to Zr healing abutments with peri-implant mucositis was comparable to those to Ti healing abutments in vivo, and can provide theoretical foundation for Zr’s clinical application.

An In Vivo Evaluation of the Fit of Zirconium-Oxide Based, Ceramic Single Crowns with Vertical and Horizontal Finish Line Preparations

2015 ◽  
Vol 24 (8) ◽  
pp. 603-609 ◽  
Author(s):  
Paolo Vigolo ◽  
Sabrina Mutinelli ◽  
Leonello Biscaro ◽  
Edoardo Stellini
Keyword(s):  
Zirconium Oxide ◽  
In Vivo Evaluation ◽  
Finish Line ◽  
Single Crowns

scholarly journals Early soft tissue response to zirconium oxide and titanium healing abutments in vivo: a study in dogs

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Min Wang ◽  
Shuang Zhang ◽  
Longjie Chen ◽  
Haixiao Zou ◽  
Yining Wang ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Zirconium Oxide ◽  
Soft Tissues ◽  
Inflammatory Cells ◽  
Tissue Response ◽  
Tnf Α ◽  
Clinical Indices ◽  
Soft Tissue Response ◽  
Crevicular Fluid

Abstract Background This study aimed to investigate the clinical characteristics and early soft tissue response to zirconium oxide (Zr) and titanium (Ti) healing abutments in dogs. Methods Eight implants (four at each hemi-mandible) were inserted after bilateral mandibular third and fourth premolars and first molar extraction in dogs. Then, two Zr and two Ti healing abutments were connected to each unilateral mandible eight weeks later. The ligation method was used to create a peri-implant mucositis model and the 24 abutments were divided into four groups: Zr or Ti healing abutments with ligation (ZrL, TiL) or non-ligation (ZrN, TiN). The clinical indices, peri-implant crevicular fluid (PICF), and inflammatory cytokines (TNF-α and IL-1β) were measured and analyzed on days 0 and 28. The dogs were then sacrificed on day 28, soft tissues around the implants were harvested, and inflammation infiltration was tested by immunohistochemistry. Normal distribution test and two-way analysis of variance was used to analyze the data. Results The results showed that the clinical indices were similar for Zr and Ti healing abutments. There was significantly more PICF in the ZrL and TiL groups compared to in the ZrN and TiN groups. The TNF-α levels in PICF were significantly different between ZrL and ZrN groups on day 28. And the TNF-α levels in PICF were significantly higher in TiL group on day 28 than that on day 0. However, the number of inflammatory cells was not significantly different between the groups as measured by immunohistochemistry. Conclusions These data indicate that soft tissue responses to Zr healing abutments with peri-implant mucositis were comparable to those of Ti healing abutments in vivo, providing a theoretical foundation for the clinical application of Zr abutments.

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