scholarly journals Surgical treatment of lower limb ischemia in diabetic patients – long-term results

2013 ◽  
Vol 6 ◽  
pp. 1078-1082 ◽  
Author(s):  
Bekir Inan ◽  
Unal Aydin ◽  
Murat Ugurlucan ◽  
Cemalettin Aydin ◽  
Melike Elif Teker
VASA ◽  
2007 ◽  
Vol 36 (2) ◽  
pp. 114-120 ◽  
Author(s):  
Geier ◽  
Mumme ◽  
Köster ◽  
Marpe ◽  
Hummel ◽  
...  

Background: Catheter-directed intraarterial thrombolytic therapy with rt-PA has been established as an alternative to surgery in selected patients with lower limb ischemia. The purpose of this study is to evaluate its long-term results and to try to identify patient variables influencing outcome. Patients and methods: The results of thrombolytic treatment for acute or subacute lower limb ischemia in 82 patients (51 male, 31 female) were retrospectively analysed. Clinical data (time of symptoms onset, clinical stage, type of affected vessel, anatomical localisation) as well as comorbidities were recorded. The success rate of thrombolysis as well as the incidence of adverse events was evaluated. Patients with initial success were followed up after a median of 52,5 months. Results: Thrombolytic therapy was successful in 67 cases (82%). An additional endovascular or surgical procedure was necessary in 39 of these patients (48%). The overall bleeding rate was 18% and the mortality and major amputation rate was 1%. 42 patients with early clinical success were available for follow-up. 34 of them (81%) were free of ischemic symptoms and the overall limb salvage rate was 96%. We could not identify factors significantly influencing early or long-term results, although there was a trend towards better results in patients with acute ischemia and in patients with occluded native arteries. Conclusions: Intraarterial local thrombolytic therapy has a relatively high initial success rate in selected patients with lower limb ischemia, but is associated with a significant number of bleeding complications. Furthermore, additional procedures are required in almost half the patients. Initial success is durable at the long-term in the majority of cases. Better selection of patients and refinements of the thrombolytic therapy might help to further improve results and lower the bleeding complications.


2015 ◽  
Vol 8 (4) ◽  
pp. 43 ◽  
Author(s):  
R. V. Deev ◽  
R. E. Kalinin ◽  
Yu. V. Chervyakov ◽  
I. N. Staroverov ◽  
I. L. Plaksa ◽  
...  

2015 ◽  
Vol 23 ◽  
pp. S74-S75 ◽  
Author(s):  
Ilia Y. Bozo ◽  
Roman V. Deev ◽  
Igor L. Plaksa ◽  
Nina D. Mzhavanadze ◽  
Yuriy V. Chervyakov ◽  
...  

2019 ◽  
Vol 0 (2) ◽  
pp. 18-26
Author(s):  
N. Yu. Litvinova ◽  
D. E. Dubenko ◽  
O. I. Kefeli-Yanovska

2004 ◽  
Vol 11 (4) ◽  
pp. 447-453 ◽  
Author(s):  
Andreas M. Lazaris ◽  
Achilleas C. Tsiamis ◽  
Guy Fishwick ◽  
Amman Bolia ◽  
Peter R. F. Bell

Author(s):  
A. S. Klinkova ◽  
O. V. Kamenskaya ◽  
A. V. Ashurkov ◽  
A. A. Karpenko ◽  
V. V. Lomivorotov

2021 ◽  
Vol 24 (1) ◽  
pp. 61-67
Author(s):  
Aleksandr N. Kosenkov ◽  
Ivan A. Vinokurov ◽  
Anastasia K. Kiselea ◽  
Svetlana V. Udovichenko

Today, there are several approaches to the treatment of critical lower limb ischemia (KINK). However, despite the high clinical effectiveness achieved, it is not always possible to achieve a high quality of life for the patient after surgery. This article presents modern aspects of surgical treatment of KINK and assesses the quality of life of patients depending on the type of intervention (literature review).


2019 ◽  
Vol 23 (2) ◽  
pp. 50
Author(s):  
O. V. Kamenskaya ◽  
A. S. Klinkova ◽  
I. Yu. Loginova ◽  
A. V. Ashurkov ◽  
V. V. Lomivorotov ◽  
...  

<p><strong>Aim.</strong> To evaluate various parameters of walking using the Walking Impairment Questionnaire (WIQ) in patients with critical lower limb ischemia (CLLI) before and one year after spinal cord stimulation (SCS). <br /><strong>Methods.</strong> In 46 patients with CLLI aged 64.5 (54.9–72.6) years, the following parameters were assessed before and one year after SCS using the WIQ questionnaire: pain, distance, speed, stairs, where 100% no restrictions when walking. <br /><strong>Results.</strong> In patients with CLLI, low WIQ values were initially identified for the scales of distance, speed, and stairs, less than 10%, and about 30% for the pain scale. One year after SCS, the values of pain, distance, and speed increased to 83.3% (68.4%–100%), 39.5% (17.9%–55.2%), and 24.4% (17.3%–35.8%), respectively, with significance at p &lt; 0.001, p = 0.004, and p = 0.005, respectively. The lowest rates were on the scale of stairs: 6.2% (3.4%–7.3%), p = 0.06. Before the SCS, the factor adversely affecting the indicators of the distance scale was diabetes mellitus (β = –0.417; p = 0.002), and the age factor adversely affected the walking speed (β = –0.544; p = 0.005). After SCS, age exerted a negative effect on the walking speed (β = –0.497; p = 0.002). The scale for stairs was negatively affected by the presence of coronary heart disease (β = –0.421; p = 0.001) or diabetes mellitus (β = –0.325; p = 0.032). <br /><strong>Conclusion</strong>. The use of SCS in patients with CLLI improves the parameters of walking in the long-term follow up after treatment, except for the ability to climb stairs. Age and the presence of diabetes mellitus or coronary heart disease are adverse factors that affect the walking parameters, both before and in the long-term period after SCS.</p><p>Received 14 March 2019. Accepted 25 July 2019.</p><p>Funding: The study did not have sponsorship.</p><p>Conflict of interest: Authors declare no conflict of interest.</p>


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