Sarcopenia is associated with increased severe postoperative complications after colon cancer surgery

Abstract Purpose Patients aged > 80 years represent an increasing proportion of colon cancer diagnoses. Selecting patients for elective surgery is challenging because of possibly compromised health status and functional decline. The aim of this retrospective, population-based study was to identify risk factors and health measures that predict short-term mortality after elective colon cancer surgery in the aged. Methods All patients > 80 years operated electively for stages I–III colon cancer from 2005 to 2016 in four Finnish hospitals were included. The prospectively collected data included comorbidities, functional status, postoperative surgical and medical outcomes as well as mortality data. Results A total of 386 patients (mean 84.0 years, range 80–96, 56% female) were included. Male gender (46% vs 35%, p = 0.03), higher BMI (51% vs 37%, p = 0.02), diabetes mellitus (51% vs 37%, p = 0.02), coronary artery disease (52% vs 36%, p = 0.003) and rheumatic diseases (67% vs 39%, p = 0.03) were related to higher risk of complications. The severe complications were more common in patients with increased preoperative hospitalizations (31% vs 15%, p = 0.05) and who lived in nursing homes (30% vs 17%, p = 0.05). The 30-day and 1-year mortality rates were 6.0% and 15% for all the patients compared with 30% and 45% in patients with severe postoperative complications (p < 0.001). Severe postoperative complications were the only significant patient-related variable affecting 1-year mortality (OR 9.60, 95% CI 2.33–39.55, p = 0.002). Conclusions The ability to identify preoperatively patients at high risk of decreased survival and thus prevent severe postoperative complications could improve overall outcome of aged colon cancer patients.

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Perirenal fat surface area as a risk factor for perioperative difficulties and 30-day postoperative complications in elective colon cancer surgery

Colorectal Disease ◽

10.1111/codi.14322 ◽

2018 ◽

Vol 20 (12) ◽

pp. 1078-1087 ◽

Cited By ~ 2

Author(s):

O. der Hagopian ◽

M. Dahlberg ◽

G. Heinius ◽

J. Nordberg ◽

J. Gustafsson ◽

...

Keyword(s):

Colon Cancer ◽

Risk Factor ◽

Postoperative Complications ◽

Surface Area ◽

Cancer Surgery ◽

Colon Cancer Surgery ◽

Elective Colon ◽

Perirenal Fat

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Clinical Frailty Scale is a useful tool for predicting postoperative complications following elective colon cancer surgery in the age of 80 years and older: A prospective, multicentre observational study

Colorectal Disease ◽

10.1111/codi.15689 ◽

2021 ◽

Author(s):

Susanna Niemeläinen ◽

Heini Huhtala ◽

Jan Andersen ◽

Anu Ehrlich ◽

Eija Haukijärvi ◽

...

Keyword(s):

Colon Cancer ◽

Postoperative Complications ◽

Observational Study ◽

Cancer Surgery ◽

Clinical Frailty Scale ◽

Colon Cancer Surgery ◽

Elective Colon

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Effect of hemodialysis on short-term outcomes after colon cancer surgery

PLoS ONE ◽

10.1371/journal.pone.0262531 ◽

2022 ◽

Vol 17 (1) ◽

pp. e0262531

Author(s):

Toshio Shiraishi ◽

Tetsuro Tominaga ◽

Takashi Nonaka ◽

Shintaro Hashimoto ◽

Kiyoaki Hamada ◽

...

Keyword(s):

Colon Cancer ◽

Minimally Invasive Surgery ◽

Postoperative Complications ◽

Minimally Invasive ◽

Invasive Surgery ◽

Hemodialysis Patients ◽

Cancer Surgery ◽

Poor Performance Status ◽

Short Term ◽

Colon Cancer Surgery

Background Hemodialysis patients who undergo surgery have a high risk of postoperative complications. The aim of this study was to determine whether colon cancer surgery can be safely performed in hemodialysis patients. Methods This multicenter retrospective study included 1372 patients who underwent elective curative resection surgery for colon cancer between April 2016 and March 2020. Results Of the total patients, 19 (1.4%) underwent hemodialysis, of whom 19 (100%) had poor performance status and 18 had comorbidities (94.7%). Minimally invasive surgery was performed in 78.9% of hemodialysis patients. The postoperative complication rate was significantly higher in hemodialysis than non-hemodialysis patients (36.8% vs. 15.5%, p = 0.009). All postoperative complications in the hemodialysis patients were infectious type. Multivariate analysis revealed a significant association of hemodialysis with complications (odds ratio, 2.9362; 95%CI, 1.1384–7.5730; p = 0.026). Conclusion Despite recent advances in perioperative management and minimally invasive surgery, it is necessary to be aware that short-term complications can still occur, especially infectious complications in hemodialysis patients.

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POSTOPERATIVE INTRAABDOMINAL COMPLICATIONS IN COLON CANCER SURGERY COMPLICATED BY BOWEL OBSTRUCTION AND PERFORATION OF THE TUMOR

Grekov s Bulletin of Surgery ◽

10.24884/0042-4625-2015-174-5-98-104 ◽

2015 ◽

Vol 174 (5) ◽

pp. 98-104 ◽

Cited By ~ 2

Author(s):

S. A. Aliev ◽

E. S. Aliev ◽

B. M. Zeinalov

Keyword(s):

Colon Cancer ◽

Surgical Treatment ◽

Postoperative Complications ◽

Retrospective Analysis ◽

Large Intestine ◽

Bowel Obstruction ◽

Abdominal Cavity ◽

Cancer Surgery ◽

Perioperative Prophylaxis ◽

Colon Cancer Surgery

The article presents a retrospective analysis of the results of surgical treatment of postoperative intraabdominal complications in 42 patients with colon cancer complicated by bowel obstruction and perforation of the tumor. The pyoinflammatory processes such as peritonitis and abscesses of abdominal cavity took a leading place in the structure of postoperative complications according to the authors. Method of «closed» decompression and intraluminal irrigation of the large intestine without wide opening of organ lumen was developed and applied into practice as perioperative prophylaxis of pyoinflammatory processes. These measures allowed reducing the rate of postoperative intraabdominal complications from 19,2 to 7,7%.

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Physical Activity and Its Impact on Colon Cancer Surgery

Case Medical Research ◽

10.31525/ct1-nct03947840 ◽

2019 ◽

Author(s):

Keyword(s):

Physical Activity ◽

Colon Cancer ◽

Cancer Surgery ◽

Colon Cancer Surgery

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Factors associated with diet failure after colon cancer surgery

Surgical Endoscopy ◽

10.1007/s00464-021-08575-y ◽

2021 ◽

Author(s):

Kiho You ◽

Dae Kyung Sohn ◽

Sung Sil Park ◽

Sung Chan Park ◽

Jae Hwan Oh ◽

...

Keyword(s):

Colon Cancer ◽

Cancer Surgery ◽

Factors Associated ◽

Colon Cancer Surgery

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A case of portal venous gas after obstructive transverse colon cancer surgery

Surgical Case Reports ◽

10.1186/s40792-019-0729-z ◽

2019 ◽

Vol 5 (1) ◽

Author(s):

Yuichiro Furutani ◽

Chikashi Hiranuma ◽

Masakazu Hattori ◽

Kenji Doden ◽

Yasuo Hashizume

Keyword(s):

Colon Cancer ◽

Conservative Treatment ◽

Anastomotic Leakage ◽

Transverse Colon ◽

Cancer Surgery ◽

Transverse Colon Cancer ◽

Bowel Necrosis ◽

Entire Area ◽

Portal Venous Gas ◽

Colon Cancer Surgery

Abstract Background Portal venous gas has traditionally been considered an inevitable harbinger of death due to its association with bowel necrosis. Recently, an increasing number of cases of portal venous gas have been reported in patients with various clinical conditions and without bowel necrosis. We herein report the case of a patient in whom portal venous gas developed after transverse colon cancer surgery. Case presentation A 69-year-old man who had transverse colon cancer underwent insertion of a transanal ileus tube for decompression. Transverse colon resection was performed on the 11th day after the insertion of the transanal ileus tube. The patient had a high fever on the 6th day after the operation. Computed tomography showed portal venous gas over the entire area of the liver and pneumatosis intestinalis in the wall of the ascending colon. There were no signs of anastomotic leakage or bowel necrosis, so we decided to use conservative therapy with fasting and antibiotics. The portal venous gas disappeared on the 19th day after the operation. The patient was discharged in good condition on the 29th day after the operation. Conclusions Conservative treatment for portal venous gas is reasonable for patients without signs of anastomotic leakage or bowel necrosis. However, it is important to carefully observe patients with portal venous gas during conservative treatment because portal venous gas may be life-threatening.

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