scholarly journals Salvage brachytherapy with or without external beam radiotherapy for oral or oropharyngeal squamous cell carcinomas in previously irradiated areas: carcinologic and toxicity outcomes of 25 patients

2021 ◽  
Vol 13 (4) ◽  
pp. 402-409
Author(s):  
Pierre-Marie Pialat ◽  
Michael Mounie ◽  
Fabien Podeur ◽  
Frédéric Gassa ◽  
Jean-Philippe Suchaud ◽  
...  
Keyword(s):  
Squamous Cell ◽  
External Beam Radiotherapy ◽  
Squamous Cell Carcinomas ◽  
External Beam ◽  
Salvage Brachytherapy

Salvage brachytherapy for local recurrence after radical prostatectomy and subsequent external beam radiotherapy

Urology ◽  
2003 ◽  
Vol 62 (6) ◽  
pp. 1068-1072 ◽  
Author(s):  
Andrea Losa ◽  
Luciano Dante Nava ◽  
Nadia Di Muzio ◽  
Paola Mangili ◽  
Barbara Longobardi ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Local Recurrence ◽  
External Beam Radiotherapy ◽  
External Beam ◽  
Salvage Brachytherapy

A PROSPECTIVE RANDOMIZED STUDY TO COMPARE THE CONCURRENT CHEMO-RADIATION VERSUS HYPO-FRACTIONATED CHEMO-RADIATION IN LOCALLY ADVANCED CERVICAL CANCER.

2021 ◽  
pp. 40-42
Author(s):  
Arpan Jana ◽  
Pabitra Das ◽  
Poulami Gupta ◽  
Phalguni Gupta
Keyword(s):  
Cervical Cancer ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
External Beam Radiotherapy ◽  
Locally Advanced ◽  
Intracavitary Brachytherapy ◽  
External Beam ◽  
Carcinoma Cervix ◽  
Advanced Carcinoma

Background: Concurrent chemo-radiation is the standard treatment worldwide for locally advanced squamous Cell carcinoma cervix. However, conventional chemo-radiotherapy is also associated with unacceptable local and systemic failure rates for locally advanced disease. Biologically squamous cell carcinoma of head- neck cancer and cervical cancer behaves quite similarly in response to radiotherapy. So, it can be expected that, altered fractionation can increase the local control in case of squamous cell carcinoma cervix than conventional radiotherapy. There is no randomised control trial for carcinoma cervix till date, which compares conventional chemo-radiation with hypo-fractionated chemo-radiation. Aims And Objectives: The present study was planned to compare local disease control and acute toxicity of conventional chemo-radiation with hypo-fractionated chemo-radiation in locally advanced carcinoma cervix. Materials And Methods: In Conventional Chemo-radiation Arm A patients (n=30) received external beam radiotherapy 50 Gy in 25 fractions in 5 weeks accompanied by weekly intravenous Cisplatin 40mg/m2 followed by intracavitary brachytherapy 7 Gy per fraction once in a week for 3 weeks. The second group of hypo-fractionated Arm B received external beam radiotherapy 45 Gy in 20 fractions in 4 weeks accompanied by weekly intravenous Cisplatin 40mg/m2 followed by intracavitary brachytherapy 9 Gy per fraction once in a week for 2 weeks. Results: Grade II diarrhea were seen more in Arm B 17 (56.66%) compare to Arm A 12(40%) and grade III diarrhea was seen 4 (3.33%) in Arm B and 2(6.66%) in Arm A. At 2 months and 6 months after completion of treatment Complete response were 25 (83.4%) in Arm A compare to 22 (73.3%) in Arm B and 20 (74.1%) in Arm A and 18 (72%) in Arm B respectively. Conclusion: Hypo-fractioned radiotherapy may be used as an alternate protocol for treatment of locally advanced carcinoma cervix with acceptable toxicities.

scholarly journals Recurrence of cancer cervix in patients treated by radical hysterectomy followed by adjuvant external beam radiotherapy

1970 ◽  
Vol 36 (2) ◽  
pp. 52-56 ◽  
Author(s):  
Fauzia Sobhan ◽  
Farzana Sobhan ◽  
Arif Sobhan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Local Recurrence ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Radical Hysterectomy ◽  
External Beam Radiotherapy ◽  
Late Recurrence ◽  
Distant Recurrence ◽  
External Beam ◽  
Distant Failure

One hundred and twenty patients with FIGO stage Ib-IIa cervical cancer who had radical hysterectomy prior to January 2003 in different hospitals of Bangladesh and thereafter received external beam pelvic radiotherapy (RT) at National Institute of Cancer Research and Hospital, Dhaka were studied. Until December 2007, 50 (42%) patients developed recurrence. Thirty-four (70%) patients experienced local recurrence, 13 (26%) distant recurrence and 2 (4%) both local and distant recurrence. Of 15 patients with distant metastasis, 6 (40%) experienced it in extra-pelvic lymph nodes. The median time to recurrence was 19 months (range 6-120 months) for local failure, 33 months (range 12-108 months) for distant failure and 25 months (range 13-36 months) for those with both local and distant failure. Eighty percent recurrences occurred within 36 months. There was significant correlation between lymph node metastasis and recurrence. All 5 (100%) patients with adenocarcinoma who had positive nodes experienced local recurrence compared with 18 of 49 (37%) squamous cell carcinoma patients with positive nodes. Recurrence more than 5 years after treatment developed in 5 (4%) patients. Mentionable, 4 (80%) out of 5 patients with late recurrence had squamous cell carcinoma with negative pelvic nodes. DOI: 10.3329/bmrcb.v36i2.6987Bangladesh Med Res Counc Bull 2010; 36: 52-56

Treatment outcomes of external-beam radiotherapy for squamous cell carcinoma of the base of the tongue

2015 ◽  
Vol 20 (5) ◽  
pp. 891-896 ◽  
Author(s):  
Yoshifumi Kawaguchi ◽  
Kinji Nishiyama ◽  
Takerou Hirata ◽  
Kouji Konishi ◽  
Shinji Otozai ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Treatment Outcomes ◽  
Squamous Cell ◽  
External Beam Radiotherapy ◽  
External Beam ◽  
Base Of The Tongue
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