scholarly journals UTILITY OF ALBUMIN CREATININE RATIO (ACR) IN MONITORING DIABETIC RETINOPATHY AND NEPHROPATHY

2021 ◽  
Vol 71 (4) ◽  
pp. 1147-51
Author(s):  
Muhammad Aneeq Haroon ◽  
Haroon Javaid ◽  
Zujaja Hina Haroon ◽  
Usama Bin Khalid ◽  
Afshan Bibi ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Type Ii Diabetes ◽  
Pearson Correlation ◽  
Military Hospital ◽  
Type Ii ◽  
Creatinine Ratio ◽  
Albumin Creatinine Ratio ◽  
Department Of Ophthalmology ◽  
Normal Albumin ◽  
Screening Marker

Objective: To evaluate Albumin Creatinine Ratio (ACR) as a screening marker for detection of early diabetic retinopathy in parallel with diabetic nephropathy. Study Design: Comparative cross sectional study. Place and Duration of Study: Department of Ophthalmology and Chemical Pathology & Endocrinology, Combined Military Hospital, Multan, from Jul 2017 to Jul 2019. Methodology: A total of 386 diagnosed patients of type II diabetes mellitus who reported for follow up and monitoring in Combined Military Hospital Multan, underwent initial screening with urine dip strip, if protein positive patients were excluded if negative patients were included in the study. Urinary albumin creatinine ratio was calculated as mg/mmol of creatinine. For staging of diabetic retinopathy; participants underwent ocular examinations. Pearson correlation was performed and ROC was constructed at different cut-offs. Results: Out of the 386 (100%) patients with type II diabetes 284 (74%) had albumin creatinine ratio <3 mg/mmol and 102 (26%) had micro albuminuria i.e. albumin creatinine ratio 3-30 mg/mmol. Among normal albumin uric cases (284) only 52 (18%) patients had mild to moderate non-proliferative diabetic retinopathy. Conclusion: Albumin creatinine ratio is associated with severity of diabetic retinopathy. Since diabetic retinopathy stages have been identified in normal albumin uric range, there is need to determine a definite cut off value (<3 mg/mmol) of ACR for using it as a screening marker for diabetic retinopathy.

scholarly journals Relationship between Diabetic Retinopathy, and Diabetic Nephropathy

2019 ◽  
Vol 48 (2) ◽  
pp. 24-27
Author(s):  
Purabi Rani Debnath ◽  
Dilip Kumar Debnath ◽  
Narayan Chandra Bhowmik
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Diabetic Nephropathy ◽  
Type Ii Diabetes ◽  
Public Health Problem ◽  
Type Ii Diabetes Mellitus ◽  
Major Public Health Problem ◽  
Type Ii ◽  
Department Of Ophthalmology ◽  
The Relationship

Diabetic nephropathy is accountable for nearly third of the world cases of last step of renal disease; it becomes a major public health problem with social and economic burden. To assess the relationship between Diabetic Retinopathy and Diabetic Nephropathy in Type II Diabetes Mellitus patients.  The present study was a cross sectional study conducted in the department of Ophthalmology at BIRDEM General Hospital, Dhaka, over a period of 12 months during  March 2018- February’ 2019 and were assess for the relationship between Retinopathy and Nephropathy. All patients of Type II Diabetes Mellitus patients with Diabetic Retinopathy and Diabetic Nephropathy were included in the study. Majority (64.0%) patients had diabetic nephropathy and 36(36.0%) had not diabetic nephropathy. Almost three fourth (73.4%) patients was found diabetic retinopathy in diabetic retinopathy and 27(54.0%) in without diabetic retinopathy. The difference was statistically significant (p<0.05) between two group. This study suggests that Diabetic Nephropathy has a significant association with the presence of Diabetic Retinopathy in persons with Type II DM. Bangladesh Med J. 2019 May; 48 (2): 24-27

Residual small artery impairment in hypertensive patients with normal albumin–creatinine ratio

2016 ◽  
Vol 50 (3) ◽  
pp. 167-171 ◽  
Author(s):  
Ashkan Eftekhari ◽  
Signe Nielsen Wiggers ◽  
Ole Norling Mathiassen ◽  
Kent Lodberg Christensen
Keyword(s):  
Creatinine Ratio ◽  
Small Artery ◽  
Albumin Creatinine Ratio ◽  
Hypertensive Patients ◽  
Normal Albumin

scholarly journals Central corneal thickness in type II diabetes mellitus: is it relatedto the severity of diabetic retinopathy?

2015 ◽  
Vol 45 ◽  
pp. 651-654 ◽  
Author(s):  
Okan TOYGAR ◽  
Selçuk SIZMAZ ◽  
Aysel PELİT ◽  
Baha TOYGAR ◽  
Özge YABAŞ KIZILOĞLU ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Type Ii Diabetes ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii

Proteomic analysis for the assessment of diabetic renal damage in humans

2004 ◽  
Vol 107 (5) ◽  
pp. 485-495 ◽  
Author(s):  
Harald MISCHAK ◽  
Thorsten KAISER ◽  
Michael WALDEN ◽  
Meike HILLMANN ◽  
Stefan WITTKE ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Type Ii Diabetes ◽  
Renal Damage ◽  
Excretion Rate ◽  
Albumin Excretion Rate ◽  
Low Grade ◽  
Type Ii ◽  
Polypeptide Pattern ◽  
Albumin Excretion ◽  
Normal Albumin

Renal disease in patients with Type II diabetes is the leading cause of terminal renal failure and a major healthcare problem. Hence early identification of patients prone to develop this complication is important. Diabetic renal damage should be reflected by a change in urinary polypeptide excretion at a very early stage. To analyse these changes, we used an online combination of CE/MS (capillary electrophoresis coupled with MS), allowing fast and accurate evaluation of up to 2000 polypeptides in urine. Employing this technology, we have examined urine samples from 39 healthy individuals and from 112 patients with Type II diabetes mellitus and different degrees of albumin excretion rate. We established a ‘normal’ polypeptide pattern in the urine of healthy subjects. In patients with Type II diabetes and normal albumin excretion rate, the polypeptide pattern in urine differed significantly from normal, indicating a specific ‘diabetic’ pattern of polypeptide excretion. In patients with higher grade albuminuria, we were able to detect a polypeptide pattern indicative of ‘diabetic renal damage’. We also found this pattern in 35% of those patients who had low-grade albuminuria and in 4% of patients with normal albumin excretion. Moreover, we could identify several of the indicative polypeptides using MS/MS sequencing. We conclude that proteomic analysis with CE/MS permits fast and accurate identification and differentiation of polypeptide patterns in urine. Longitudinal studies should explore the potential of this powerful diagnostic tool for early detection of diabetic renal damage.

scholarly journals The Relationship of Illness Perception and Medication Adherence in Patients With Diabetes Mellitus Type II

2021 ◽  
Author(s):  
Sina Sabeti Bilondi ◽  
Ali Delshad Noghabi ◽  
Hosein Aalami
Keyword(s):  
Medication Adherence ◽  
Type Ii Diabetes ◽  
Pearson Correlation ◽  
Illness Perception ◽  
Personal Control ◽  
Diabetic Patients ◽  
Type Ii ◽  
Diabetes Clinic ◽  
The Mean ◽  
The Relationship

Abstract Background: One of the most well-known chronic diseases in the world is diabetes. Disease perception is the patient's organized cognitive representation of his or her illness and can affect treatment adherence. The aim of this study was to investigate the relationship between illness perception and adherence to the medical regimen in patients with type II diabetes. Methods: This descriptive-analytical cross-sectional study was performed on 260 patients with type II diabetes referred to Gonabad Diabetes Clinic by systematic random sampling in 2019. Data collection tools were demographic questionnaire, Morisky medication Adherence Scale (MMAS-8), and Brief illness Perception Questionnaire (BIPQ). Data were analyzed by SPSS 20 software. And using descriptive statistics, Pearson correlation coefficient. P < 0.05 was considered significant. Results: The results showed that the mean score of illness perception of type II diabetes was 46.39 ± 9.45 (range 0-70) and the mean score of medication Adherence was 2.93 ± 1.9 (range 0-8). The results of Pearson correlation test showed a significant relationship between illness perception and medication Adherence (P <0.001, r = 0.199). Also, the regression model showed that the dimensions of disease comprehension and personal control from illness perception were significantly related to medication Adherence of type II diabetic patients (P <0.001). Conclusion: By measuring the level of illness perception, the degree of medication Adherence can be predicted. Therefore, strengthening the illness perception in order to medication Adherence seems to be an important therapeutic strategy in educational interventions. Keywords: illness perception, medication Adherence, type II diabetes

A STUDY ON THE CORRELATION OF DIABETIC RETINOPATHY IN TYPE II DIABETES MELLITUS WITH SERUM VITAMIN D LEVELS

2021 ◽  
pp. 78-80
Author(s):  
Barnali Bhattacharyya Thakur ◽  
Keshab Bora ◽  
Sherin Gogoi
Keyword(s):  
Diabetes Mellitus ◽  
Vitamin D ◽  
Diabetic Retinopathy ◽  
Type Ii Diabetes ◽  
Serum Vitamin ◽  
Diabetic Patients ◽  
Type I ◽  
Type Ii ◽  
Serum Vitamin D ◽  
Vitamin D Levels

INTRODUCTION: Diabetes mellitus is a major public health problem with signicant morbidity and mortality. Diabetic retinopathy is one of the most common microvascular complications of Diabetes mellitus causing blindness. Vitamin D is a fat soluble vitamin involved in maintenance of mineral homeostasis and bone remodelling. Vitamin D deciency is highly prevalent in type I and type II Diabetes. 38 diabetic without ocular disease a METHOD: nd 30 diabetic with retinopathy were taken as cases and 38 age sex matched healthy persons were taken as controls. Serum Vit D and glucose were estimated and retinopathy was diagnosed by fundus examination. The results were statistically analysed. Statistica RESULTS: l analysis of the results shows a negative correlation between FBS and HbA1C with Vitamin D level in diabetic retinopathy patients. Patients CONCLUSION: with Diabetic retinopathy has lower serum Vitamin D level than diabetic patients without retinopathy.

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