Role of Thromboelastography and Thromboelastometry in predicting risk of hypercoagulability and thrombosis in critically ill COVID-19 patients - A Qualitative Systematic Review

PurposePancreatic carcinoma is one of the leading causes of cancer-related mortality. At time of diagnosis, 30% of patients present with a locally advanced unresectable but nonmetastatic pancreatic carcinoma (LAPC). The French program Standards, Options, and Recommendations was promoted to conduct a qualitative systematic review to evaluate the role of radiotherapy in patients with LAPC.MethodsA search to identify eligible studies was undertaken using the MEDLINE database. All phase III randomized trials and systematic reviews evaluating the role of radiotherapy in LAPC were included, together with some noncontrolled studies if no phase III trials were retrieved. The quality and clinical relevance of the studies were evaluated using validated checklists, which allowed associating each result with a level of evidence.ResultsTwenty-one studies were included, as follows: two meta-analyses, 13 randomized trials, and six nonrandomized trials. Chemoradiotherapy increases overall survival when compared with best supportive care (level of evidence C) or with exclusive radiotherapy (level B1), but is more toxic (level B1). Chemoradiotherapy is not superior to chemotherapy in terms of survival (level B1) and increases toxicity (level A). Recent data favor limited irradiation to the tumor volume (level C). Fluorouracil is still the reference chemotherapy in association with radiotherapy (level B1). Induction chemotherapy before chemoradiotherapy improves survival (level C).ConclusionNo standard treatment exists, but there are two options for treatment of LAPC; these are gemcitabine-based chemotherapy and chemoradiotherapy. Induction chemotherapy followed by a chemoradiotherapy is a promising strategy for selection of patients without early metastatic/progressing disease.

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The role of the family in supporting the self-management of chronic conditions: A qualitative systematic review

Journal of Clinical Nursing ◽

10.1111/jocn.13775 ◽

2017 ◽

Vol 27 (1-2) ◽

pp. 22-30 ◽

Cited By ~ 33

Author(s):

Lisa Whitehead ◽

Elisabeth Jacob ◽

Amanda Towell ◽

Ma'en Abu-qamar ◽

Amanda Cole-Heath

Keyword(s):

Systematic Review ◽

Chronic Conditions ◽

The Self ◽

Self Management ◽

Qualitative Systematic Review ◽

The Family

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The role of document analysis in health policy analysis studies in low and middle-income countries: Lessons for HPA researchers from a qualitative systematic review

Health Policy OPEN ◽

10.1016/j.hpopen.2020.100024 ◽

2021 ◽

Vol 2 ◽

pp. 100024

Author(s):

Naomi Karen Kayesa ◽

Maylene Shung-King

Keyword(s):

Systematic Review ◽

Health Policy ◽

Policy Analysis ◽

Document Analysis ◽

Middle Income ◽

Middle Income Countries ◽

Health Policy Analysis ◽

Qualitative Systematic Review ◽

Low And Middle Income

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Perceived factors to providing palliative care for patients with cancer - a qualitative systematic review

Oncology Reviews ◽

10.4081/oncol.2020.463 ◽

2020 ◽

Vol 14 (1) ◽

Author(s):

Haydeh Heidari ◽

Marjan Mardani-Hamooleh ◽

Masoud Amiri

Keyword(s):

Systematic Review ◽

Palliative Care ◽

Web Of Science ◽

Organizational Factors ◽

Patients With Cancer ◽

Qualitative Systematic Review ◽

Patient’S Experience ◽

Synthesis Approach ◽

Qualitative Literature

Palliative care (PC) is one of the necessary cares given throughout a patient’s experience with cancer. The aim of this study was to identify the perceived factors to providing PC for patients with cancer. Our study was a systematic review of qualitative literature. To this end, electronic databases, including CINAHL, PubMed, PsycINFO, Ovid, and Web of Science as well as Persian databases were searched and qualitative studies on the role of PC in patients with cancer published between Jan 2008 and Dec 2017 were selected. Generally, 12 studies were reviewed. A thematic synthesis approach was used to analyze the data. Exploring the selected articles, the findings on the perceived factors to providing PC for patients with cancer were categorized into three themes, including organizational factors, ethical factors, and psychological factors. This qualitative systematic review expands our knowledge about factors influencing the provision of PC for patients with cancer. It is necessary for health system managers and caregivers to pay attention to all aforesaid factors in order to improve PC for cancer patients.

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Young People Who Display Harmful Sexual Behaviors and Their Families: A Qualitative Systematic Review of Their Experiences of Professional Interventions

Trauma Violence & Abuse ◽

10.1177/1524838018770414 ◽

2018 ◽

Vol 21 (3) ◽

pp. 456-469 ◽

Cited By ~ 2

Author(s):

Fiona Campbell ◽

Andrew Booth ◽

Simon Hackett ◽

Anthea Sutton

Keyword(s):

Systematic Review ◽

Young People ◽

Sexual Behaviors ◽

Young Person ◽

Sexual Offenses ◽

Qualitative Systematic Review ◽

Role Of Parents ◽

Critical Components ◽

Professional Interventions

It is estimated that 30–50% of all childhood sexual abuse involves other young people as perpetrators. The treatment of harmful sexual behavior (HSB) in young people has evolved from interventions developed for use with adult perpetrators of sexual offenses. Increasingly, these approaches were not seen as appropriate for use with young people. The purpose of this qualitative systematic review was to establish what intervention components are viewed as acceptable or useful by young people and their families in order to inform the development of interventions for young people with HSB. We conducted searches across 14 electronic databases as well as contacting experts to identify relevant studies. Thirteen qualitative studies were included in the analysis, reporting findings from intervention studies from the United Kingdom, United States, New Zealand, Australia, and Ireland. Thematic analysis was used to combine findings from the studies of young people and parent/carers views. Five key themes were identified as critical components of successful interventions for young people with HSB. These included the key role of the relationship between the young person and practitioner, the significance of the role of parents and carers, the importance of considering the wider context in which the abuse has occurred, the role of disclosure in interventions, and the need to equip young people with skills as well as knowledge. The evidence was limited by the small number of studies that were mainly from the perspectives of adolescent males.

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