scholarly journals REDUCTION OF BONE MINERAL DENSITY IN WOMEN OF REPRODUCTIVE AGE, DESCENDANTS OF THOSE IRRADIATED AS A RESULT OF NUCLEAR TESTS

InterConf ◽  
2021 ◽  
pp. 774-781
Author(s):  
Zh. Ryspaeva ◽  
G. Tanysheva ◽  
Z. Ahmedzianova ◽  
A. Kapenova

Aim of research: To determine the frequency and degree of decrease in bone mineral density in women of reproductive age who are descendants of persons exposed to radiation as a result of nuclear tests at the Semipalatinsk test site. The study included 383 women, descendants of non-irradiated and irradiated II and III generations in the female line. The parameters of bone mineral density in 2 age groups (II generation - 1962-1987 year of birth and III generation – 1988-1996 year of birth) were studied by ultrasound densitometry. It was revealed that women of reproductive age with irradiated ancestors of the second and third generation, who lived in areas of maximum and extreme radiation risk, had a relative decrease in bone mineral density, which was statistically significant in relation to the descendants of persons who were not exposed to chronic anthropogenic sources of ionizing radiation. There were statistically significant relationship between exposure ancestors II and III generation and indicators BMD their offspring, women of reproductive age. It is possible to predict the rapid development of involutional osteoporosis in women-descendants of irradiated patients in the ІІ and ІІІ generation.

2018 ◽  
Vol 18 (2) ◽  
pp. 117-120
Author(s):  
Fatima Jesmin ◽  
Fatima Begum ◽  
CAHM Enamullah ◽  
Faridul Alam

Objective: The objective of this study was to assess the relationship between Bone Mineral Density (BMD) and parity in women of reproductive age group.Materials and methods: A cross sectional analytical study was carried out where the study population was women of reproductive age group (15 to 49 years of age). A total of 180 women were included as study subjects and the sampling technique was non random sampling. The study population was selected from healthy women of reproductive age group. Data about age, height, weight and history of parity were taken. BMD was measured by DEXA. Then relationship between BMD and parity were analysed.Results: In this study, a large number, 79 (43.9%) of participants were in age group of 29-38 years with mean± SD 35.46±6.75 years. Association between BMD and age of the study subjects represented that values of BMD decreased with increasing age (P<0.05). Bivariate analysis between BMD and parity revealed that values of BMD at lumbar spine and femur were associated with parity and it was also showed that the BMD of nulliparous women and one-to-two parity groups were significantly higher than multiparous (≥3 parity) women (P<0.05).Conclusion: From overall analysis of this study it can be concluded that BMD at lumbar spine and femur in women of reproductive age group was negatively associated with number of parity.Bangladesh J. Nuclear Med. 18(2): 117-120, July 2015


2020 ◽  
Vol 2 (37) ◽  
pp. 7-11
Author(s):  
O. V. Dobrovolskaya ◽  
N. V. Dyomin ◽  
A. V. Smirnov ◽  
I. A. Shornikova ◽  
N. V. Toroptsova

The article is devoted to the study of bone mineral density (BMD) in women of reproductive age suffering from rheumatic diseases (RD). A survey was conducted of 134 women — 94 patients with RD (rheumatoid arthritis, systemic scleroderma and psoriatic arthritis) and 40 people without RD. Reduced BMD was detected significantly more often in the group of patients with RE compared with the healthy control (25 and 8 %, respectively; p = 0.0213). Patients with RD showed a direct association of BMD values in all measurement areas with height, weight, body mass index, serum vitamin D concentration, and the reverse — with a cumulative dose of glucocorticoids; For MPC of the proximal femur, an additional relationship was revealed with the duration of RD. Thus, a quarter of women with RD in reproductive age need to be monitored, and in the presence of fractures, treatment of osteoporosis.


Nutrients ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1669
Author(s):  
Eloy Méndez-Gallegos ◽  
Graciela Caire-Juvera ◽  
Humberto Astiazarán-García ◽  
Rosa Méndez-Estrada

The objective of this study was to compare current measurements of bone mineral density (BMD) of the lumbar spine (LS), femoral neck (FN), and total femur (TF) regions with initial values recorded 12 years ago in women from Northwest Mexico, and evaluate their correlation with dietary, anthropometric, and reproductive variables. BMD was assessed by Dual-energy X-ray absorptiometry. Participants were grouped as follows: Nulliparous (G1); women who were mothers 12 years ago (G2); and women who were nulliparous 12 years ago, but are now mothers (G3). In all three groups, current LS BMD was higher than initial (p ≤ 0.05) and current TF BMD in G2 was higher than initial values (p ≤ 0.05). When comparing current FN and TF BMD among the three groups, G2 had higher values than G3 (p ≤ 0.05). G2 also showed higher LS BMD than G1 and G3 (p = 0.006). Age at menarche was inversely-correlated with FN and TF BMD in G1 (p < 0.01), while the body mass index (BMI) correlated positively with all three bone regions in G2 (p < 0.05). This study shows that in women without and with children, age at menarche, BMI, and age were factors associated to BMD in healthy subjects in reproductive age.


2011 ◽  
Vol 20 (4) ◽  
pp. 453-460 ◽  
Author(s):  
Dalia G. Mahran ◽  
Mostafa Hussein ◽  
Osama Farouk

2021 ◽  
Vol 74 (2) ◽  
pp. 303-309
Author(s):  
Sergii V. Shevchuk ◽  
Liudmyla P. Denyshchych ◽  
Liubov I. Marynych ◽  
Inna P. Kuvikova ◽  
Iryna V. Kurilenko ◽  
...  

The aim: To study the peculiarities of bone mineral density in the Ukrainian population of women of different reproductive age with systemic lupus erythematosus and to evaluate its connection with traditional and specific (typical for systemic lupus erythematosus) risk factors. Materials and methods: A total of 91 women with systemic lupus erythematosus and 29 healthy individuals were examined. Along with the clinical study of the activity and severity of the disease, the serum levels of interleukin-6 were determined by the enzyme immunoassay. The peculiarities of bone mineral density were studied using dual-energy X-ray absorptiometry. The presence of fractures was evaluated by the X-ray method. Results: Patients with systemic lupus erythematosus frequently suffer from reduced bone mineral density. Reduced bone mineral density and the appearance of fragility fractures are associated with patients’ age, disease duration, damage index, inflammatory activity, and cumulative dose of glucocorticoids. Conclusions: Progressive reduced bone mineral density in patients with systemic lupus erythematosus occurs not only during the aging process of a woman, but is also associated with a number of systemic lupus erythematosus – related osteoporosis risk factors.


Sign in / Sign up

Export Citation Format

Share Document