The effect of cardiovascular risk factors and coronary atherosclerosis severity on long term graft patency rate in patients underwent coronary artery bypass graft surgery

Objective. This study evaluated the long-term clinical and angiographic outcomes of coronary artery reconstruction for a diffusely diseased coronary artery without endarterectomy.Material and Methods. We retrospectively reviewed 660 consecutive patients (mostly men (89.5%), mean age 68.3 ± 7.4 years) who underwent coronary artery bypass grafting in combination with coronary artery reconstruction between 2003 and 2016. 558 operated on patients (84.5%) were followed up for a mean of 94.3 ± 31.2 months.Results. Long-term survival was 83.2% (95% confidence interval: 74.5–89.3); freedom from cardiac death was 97.4 ± 1.2%; and freedom from major adverse cardiac and cerebrovascular events was 64.7 ± 4.1%. Independent predictors of long-term mortality were age at surgery (< 70 years, p < 0.001), chronic obstructive pulmonary disease (p = 0.007), peripheral arterial disease (p = 0.002), diabetes mellitus (p = 0.013) and chronic kidney disease (p = 0.034). The arterial graft patency rate was 95.2%, and the vein graft patency rate was 75.4%.Conclusion. Coronary artery bypass grafting in conjunction with coronary artery reconstruction without endarterectomy confers satisfactory long-term clinical outcomes with high probability of freedom from cardiac death and angina pectoris, good rates of angiographic patency of arterial grafts and favorable rates of vein graft patency.

Download Full-text

Long-term internal thoracic artery bypass graft patency and geometry assessed by multidetector computed tomography

The International Journal of Cardiovascular Imaging ◽

10.1007/s10554-011-9962-7 ◽

2011 ◽

Vol 28 (6) ◽

pp. 1577-1583 ◽

Cited By ~ 3

Author(s):

Mette Zacho ◽

Sune Damgaard ◽

Nikolaj Thomas Lilleoer ◽

Henning Kelbaek ◽

Daniel Steinbrüchel ◽

...

Keyword(s):

Computed Tomography ◽

Multidetector Computed Tomography ◽

Internal Thoracic Artery ◽

Artery Bypass ◽

Bypass Graft ◽

Graft Patency ◽

Artery Bypass Graft

Download Full-text

Internal Mammary Artery Bypass Graft—Long-term Patency Rate and Follow-up

The Annals of Thoracic Surgery ◽

10.1016/s0003-4975(10)64356-1 ◽

1974 ◽

Vol 18 (3) ◽

pp. 269-279 ◽

Cited By ~ 63

Author(s):

Earle B. Kay ◽

H. Naraghipour ◽

R.A. Beg ◽

M. DeManey ◽

A. Tambe ◽

...

Keyword(s):

Patency Rate ◽

Internal Mammary Artery ◽

Artery Bypass ◽

Bypass Graft ◽

Artery Bypass Graft ◽

Internal Mammary

Download Full-text

Acute and Chronic Changes in Platelet Volume and Count After Cardiopulmonary Bypass Induced Thrombocytopenia in Man

Thrombosis and Haemostasis ◽

10.1055/s-0038-1651061 ◽

1987 ◽

Vol 57 (01) ◽

pp. 55-58 ◽

Cited By ~ 37

Author(s):

J F Martin ◽

T D Daniel ◽

E A Trowbridge

Keyword(s):

Platelet Count ◽

Mean Platelet Volume ◽

Artery Bypass ◽

Bypass Graft ◽

Control Group ◽

Artery Bypass Graft ◽

Platelet Volume ◽

Young Males ◽

The Mean

SummaryPatients undergoing surgery for coronary artery bypass graft or heart valve replacement had their platelet count and mean volume measured pre-operatively, immediately post-operatively and serially for up to 48 days after the surgical procedure. The mean pre-operative platelet count of 1.95 ± 0.11 × 1011/1 (n = 26) fell significantly to 1.35 ± 0.09 × 1011/1 immediately post-operatively (p <0.001) (n = 22), without a significant alteration in the mean platelet volume. The average platelet count rose to a maximum of 5.07 ± 0.66 × 1011/1 between days 14 and 17 after surgery while the average mean platelet volume fell from preparative and post-operative values of 7.25 ± 0.14 and 7.20 ± 0.14 fl respectively to a minimum of 6.16 ± 0.16 fl by day 20. Seven patients were followed for 32 days or longer after the operation. By this time they had achieved steady state thrombopoiesis and their average platelet count was 2.44 ± 0.33 × 1011/1, significantly higher than the pre-operative value (p <0.05), while their average mean platelet volume was 6.63 ± 0.21 fl, significantly lower than before surgery (p <0.001). The pre-operative values for the platelet volume and counts of these patients were significantly different from a control group of 32 young males, while the chronic post-operative values were not. These long term changes in platelet volume and count may reflect changes in the thrombopoietic control system secondary to the corrective surgery.

Download Full-text