scholarly journals The Portable Neuromodulation Stimulator: Targeting Neuroplasticity for Balance or Gait Deficit

2021 ◽  
Vol 1 (8) ◽  
Author(s):  
Sara D. Khangura
Keyword(s):  
Multiple Sclerosis ◽  
Health Care ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Health Technology ◽  
Decision Makers ◽  
Horizon Scanning ◽  
Moderate Traumatic Brain Injury ◽  
Care Decision ◽  
Gait Impairments

CADTH’s Horizon Scanning Service identifies new and emerging technologies that may be of interest to health care decision-makers in Canada Health Technology Update articles generally focus on a single technology or intervention. This Horizon Scan presents a brief summary of information relevant to the Portable Neuromodulation Stimulator, designed to be used in conjunction with physical therapy to improve balance or gait impairments associated with mild-to-moderate symptoms of multiple sclerosis or mild-to-moderate traumatic brain injury.

scholarly journals Pharyngeal Electrical Stimulation for the Treatment of Dysphagia Associated With Neurologic Conditions

2021 ◽  
Vol 1 (9) ◽  
Author(s):  
Anusree Subramonian
Keyword(s):  
Health Care ◽  
Electrical Stimulation ◽  
Emerging Technology ◽  
Decision Makers ◽  
Health Care Decision ◽  
Health Technologies ◽  
Potential Interest ◽  
Horizon Scanning ◽  
Available Information ◽  
Care Decision

Horizon Scan reports provide brief summaries of information regarding new and emerging health technologies. These technologies are identified through the CADTH Horizon Scanning Service as topics of potential interest to health care decision-makers in Canada. This Horizon Scan summarizes the available information regarding an emerging technology, Phagenyx, a pharyngeal electrical stimulation device for the treatment of difficulty swallowing associated with neurologic conditions.

scholarly journals Barricaid Spinal Implant Device

2021 ◽  
Vol 1 (8) ◽  
Author(s):  
Diksha Kumar
Keyword(s):  
Health Care ◽  
Emerging Technology ◽  
Decision Makers ◽  
Spinal Implant ◽  
Health Technologies ◽  
Horizon Scanning ◽  
Spinal Disc ◽  
Available Information ◽  
Spinal Disc Herniation ◽  
Care Decision

Horizon Scan reports provide brief summaries of information regarding new and emerging health technologies. These technologies are identified through the CADTH Horizon Scanning Service as topics of potential interest to health care decision-makers in Canada. This Horizon Scan summarizes the available information regarding an emerging technology, Barricaid — a spinal implant device for those at risk of recurrent spinal disc herniation.

scholarly journals 3,6′-Dithiopomalidomide Ameliorates Hippocampal Neurodegeneration, Microgliosis and Astrogliosis and Improves Cognitive Behaviors in Rats with a Moderate Traumatic Brain Injury

2021 ◽  
Vol 22 (15) ◽  
pp. 8276
Author(s):  
Pen-Sen Huang ◽  
Ping-Yen Tsai ◽  
Ling-Yu Yang ◽  
Daniela Lecca ◽  
Weiming Luo ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Short Term Memory ◽  
Post Injury ◽  
Behavioral Deficits ◽  
Cognitive Behaviors ◽  
Moderate Traumatic Brain Injury ◽  
Short And Long Term ◽  
Behavioral Impairments ◽  
Hippocampal Neurodegeneration

Traumatic brain injury (TBI) is a leading cause of disability and mortality worldwide. It can instigate immediate cell death, followed by a time-dependent secondary injury that results from disproportionate microglial and astrocyte activation, excessive inflammation and oxidative stress in brain tissue, culminating in both short- and long-term cognitive dysfunction and behavioral deficits. Within the brain, the hippocampus is particularly vulnerable to a TBI. We studied a new pomalidomide (Pom) analog, namely, 3,6′-dithioPom (DP), and Pom as immunomodulatory imide drugs (IMiD) for mitigating TBI-induced hippocampal neurodegeneration, microgliosis, astrogliosis and behavioral impairments in a controlled cortical impact (CCI) model of TBI in rats. Both agents were administered as a single intravenous dose (0.5 mg/kg) at 5 h post injury so that the efficacies could be compared. Pom and DP significantly reduced the contusion volume evaluated at 24 h and 7 days post injury. Both agents ameliorated short-term memory deficits and anxiety behavior at 7 days after a TBI. The number of degenerating neurons in the CA1 and dentate gyrus (DG) regions of the hippocampus after a TBI was reduced by Pom and DP. DP, but not Pom, significantly attenuated the TBI-induced microgliosis and DP was more efficacious than Pom at attenuating the TBI-induced astrogliosis in CA1 and DG at 7D after a TBI. In summary, a single intravenous injection of Pom or DP, given 5 h post TBI, significantly reduced hippocampal neurodegeneration and prevented cognitive deficits with a concomitant attenuation of the neuroinflammation in the hippocampus.

Confirmatory factor structure of the Center for Epidemiologic Studies-Depression scale (CES-D) in mild-to-moderate traumatic brain injury

Brain Injury ◽  
2006 ◽  
Vol 20 (5) ◽  
pp. 519-527 ◽  
Author(s):  
Stephen R. McCauley ◽  
Claudia Pedroza ◽  
Sharon A. Brown ◽  
Corwin Boake ◽  
Harvey S. Levin ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Factor Structure ◽  
Depression Scale ◽  
Epidemiologic Studies ◽  
Moderate Traumatic Brain Injury ◽  
Confirmatory Factor

scholarly journals Utilization and Costs of Health Care after Geriatric Traumatic Brain Injury

2012 ◽  
Vol 29 (10) ◽  
pp. 1864-1871 ◽  
Author(s):  
Hilaire J. Thompson ◽  
Sharada Weir ◽  
Frederick P. Rivara ◽  
Jin Wang ◽  
Sean D. Sullivan ◽  
...  
Keyword(s):  
Health Care ◽  
Traumatic Brain Injury ◽  
Brain Injury

Predictors of deterioration indicating a requirement for surgery in mild to moderate traumatic brain injury

2014 ◽  
Vol 127 ◽  
pp. 97-100 ◽  
Author(s):  
Eiichi Suehiro ◽  
Hiroyasu Koizumi ◽  
Yuichi Fujiyama ◽  
Hiroshi Yoneda ◽  
Michiyasu Suzuki
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Moderate Traumatic Brain Injury
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