Background::
Phyto, or plant-derived metal nanoparticles are an interesting and intensive studied group of
green synthesized nanoparticles. In the last decade, numerous medicinal plant extracts were used to the synthesis of stable
gold or silver nanoparticles with diverse biological effects, such as antioxidant activity, antimicrobial activity, antiinflammatory
activity, hypoglycemic effect, antitumor activity and catalytic activity.
Results::
This review has systematized and discussed information from the last 5 years about the research regarding
antitumor/anticancer potential of gold nanoparticles obtained via medicinal plant extracts, with special attention on
their selective cytotoxicity on tumor cells and on their mechanism of action, in vitro and in vivo assessments.
Conclusion::
Much more in vivo and clinical studies are needed before considering phyto-synthesized gold
nanoparticles as significant for future medicine.