Acute Liver Failure in Patients with Classic Heat Stroke

Background: Classic heat stroke is defined by a core temperature greater than 40° C, severe dehydration and neurological alterations. Patients with liver disease due to heat stroke have been described, mostly by exercise. Hepatic failure is defined as the presence of a coagulopathy accompanied by any degree of hepatic encephalopathy. The primary objective of the study lies in the fact that patients who developed acute liver failure during their hospital stay had a higher risk of mortality. Methods: A retrospective, analytical study of patients admitted to the General Hospital of Mexicali who suffered from classic heat stroke from March 2006 through August 2010, and a second period from June 2018 to August 2019. Results: Fifty patients were recruited, the group included 48 (96%) male, with a total of 10 fatalities, representing 20%. INR greater than 1.5, AST and ALT levels were not related to an increased mortality rate. Conclusion: Neither transaminase levels, nor liver failure, were related to a higher mortality rate in this cohort of patients with classic heat stroke.

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An Analytical Study on Acute Liver Injury in Patients Caused by Classic Heat stroke

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i46a32860 ◽

2021 ◽

pp. 219-223

Author(s):

Kirti Mishra ◽

Pallavi Srivatava

Keyword(s):

Liver Failure ◽

Acute Liver Failure ◽

Hospital Stay ◽

Analytical Study ◽

Heat Stroke ◽

International Normalized Ratio ◽

The Body ◽

Medical Emergency ◽

Time Period ◽

Risk Of Mortality

Heat Stroke is a kind of medical emergency that can cause severe dehydration and neurological changes as a result multi-organ injuries or failure could be possible. Heat strokes occur when the body temperature exceeds 40 0C due to external heat and humidity. The liver is widely affected by heatstroke that’s why taking care of patients suffering from heatstroke is very important. Various studies have been reported in the literature regarding acute liver failure but none of the studies discussed acute liver failure during the hospital stay. Patients during their hospital stay will have a higher risk of mortality due to heatstroke. In this paper, an analytical study has been done on admitted patients to a government hospital in India. These patients are suffered from heatstroke from April 2007 to September 2011 and a second time period from July 2018 to September 2019. The sample includes 60 patients with 58 (97%) males having a totaled number of 12 fatalities. The observed International Normalized ratio (INR) parameter is greater than 1.6 and no increased mortality has been noticed, aspartate aminotransferase (AST), as well as alanine aminotransferase (ALT) levels, were not associated with an increased mortality rate.

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A Case of Exertional Heat Stroke Complicated by Hypoxic Hepatitis

Case Reports in Emergency Medicine ◽

10.1155/2020/8724285 ◽

2020 ◽

Vol 2020 ◽

pp. 1-4

Author(s):

Bertram K. Woitok ◽

Shawki Bahmad ◽

Gregor Lindner

Keyword(s):

Supportive Care ◽

Liver Failure ◽

Acute Liver Failure ◽

Multiorgan Failure ◽

Heat Stroke ◽

Exertional Heat Stroke ◽

Hypoxic Hepatitis ◽

Threatening Condition ◽

Life Threatening ◽

Delayed Referral

Background.Exertional heat stroke is a life-threatening condition often complicated by multiorgan failure. We hereby present a case of a 25-year-old male presenting with syncope after a 10 km run in 28°C outside temperature who developed acute liver failure. Case Presentation. Initial temperature was found to be 41.1°C, and cooling measures were rapidly applied. He suffered from acute renal failure and rhabdomyolysis and proceeded to acute liver failure (ASAT 6100 U/l and ALAT 6561 U/l) due to hypoxic hepatitis on day 3. He did not meet criteria for emergency liver transplantation and recovered on supportive care. Conclusions. Acute liver failure due to heat stroke is a life-threatening condition with often delayed onset, which nevertheless resolves on supportive care in the majority of cases; thus, a delayed referral to transplant seems to be reasonable.

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Exertional heat stroke associated with acute liver failure in a young refugee. Implications in the era of social-economic crisis

Journal of Gastrointestinal and Liver Diseases ◽

10.15403/jgld-302 ◽

2019 ◽

Vol 28 (3) ◽

pp. 364-364

Author(s):

Dimitrios S. Politis ◽

Gerasimos Baltagiannis ◽

Nikolaos Tzampouras ◽

George N Kalambokis ◽

Vasileios Koulouras ◽

...

Keyword(s):

Liver Failure ◽

Acute Liver Failure ◽

Economic Crisis ◽

Social Economic ◽

Heat Stroke ◽

Exertional Heat Stroke

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High-volume plasma exchange in a patient with acute liver failure due to non-exertional heat stroke in a sauna

Journal of Clinical Apheresis ◽

10.1002/jca.21315 ◽

2014 ◽

Vol 29 (5) ◽

pp. 281-283 ◽

Cited By ~ 10

Author(s):

Kuan-Jung Chen ◽

Tso-Hsiao Chen ◽

Yuh-Mou Sue ◽

Tzay-Jinn Chen ◽

Chung-Yi Cheng

Keyword(s):

Liver Failure ◽

Acute Liver Failure ◽

Plasma Exchange ◽

Heat Stroke ◽

High Volume ◽

Exertional Heat Stroke

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Acute Liver Failure: A Rare Primary Sequela of Exertional Heat Stroke

The American Journal of Gastroenterology ◽

10.14309/00000434-201810001-02254 ◽

2018 ◽

Vol 113 (Supplement) ◽

pp. S1277

Author(s):

Lindsay Clarke ◽

Daniel Szvarca ◽

Danielle Davison ◽

Bedoor Alabbas ◽

Marie Borum

Keyword(s):

Liver Failure ◽

Acute Liver Failure ◽

Heat Stroke ◽

Exertional Heat Stroke

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Exertional Heat Stroke in a Young Athlete Resulting in Acute Liver Failure

Journal of Pediatric Gastroenterology and Nutrition ◽

10.1097/mpg.0000000000000562 ◽

2016 ◽

Vol 63 (4) ◽

pp. e75-e76 ◽

Cited By ~ 5

Author(s):

Jacob A. Kurowski ◽

Henry C. Lin ◽

Saeed Mohammad ◽

Steven Krug ◽

Estella M. Alonso

Keyword(s):

Liver Failure ◽

Acute Liver Failure ◽

Heat Stroke ◽

Young Athlete ◽

Exertional Heat Stroke

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A Surviving Child from Acute Liver Failure after an Ingestion of Cassia occidentalis Seeds

Journal of Tropical Pediatrics ◽

10.1093/tropej/fmaa087 ◽

2020 ◽

Author(s):

Songpon Getsuwan ◽

Pornthep Tanpowpong ◽

Satariya Trakulsrichai ◽

Pattana Sornmayura ◽

Suporn Treepongkaruna

Keyword(s):

Liver Transplantation ◽

Mortality Rate ◽

Cardiogenic Shock ◽

Liver Failure ◽

Acute Liver Failure ◽

Renal Tubular Acidosis ◽

Sodium Benzoate ◽

Cassia Occidentalis ◽

Fresh Seed ◽

Renal Tubular

Abstract Cassia occidentalis toxicity is thought to be uncommon; however, several cases have been described with acute hepatomyoencephalopathy with a high-mortality rate. We report a previously healthy, 2-year-old girl who developed acute liver failure after fresh seed ingestion. Without a specific antidote, we decided to implement supportive measures and medications including lactulose, sodium benzoate and N-acetylcysteine. The patient also experienced with cardiogenic shock and transient distal renal tubular acidosis, which were all spontaneously resolved. The liver chemistries returned to normal 3 months after the ingestion, without receiving liver assisted device or liver transplantation.

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