scholarly journals FDG embolism mimicking lung metastasis

Author(s):  
Amin Haghighat Jahromi ◽  
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Carl K Hoh ◽  

2-[18F]-FDG embolism artifact is a PET pitfall that may cause misinterpretation as lung metastasis. This rare phenomenon results from clumping of the radiotracer with platelet aggregates during intravenous administration. It should be considered, especially if there is no corroborating anatomic correlate for focal pulmonary FDG activity and if the radiotracer is administered through a central venous catheter. Herein, we present images of a 3-year-old girl with history of abdominal neuroblastoma and lung metastasis, showing FDG embolism artifact, subsequently resolved in the repeat imaging. Our case reinforces the importance of knowing this artifact as misinterpretation can have a significant effect on patient management.

2021 ◽  
pp. 1-7
Author(s):  
Amnah Mohammed Howthan ◽  
◽  
Nahed Ahmed Mersal ◽  
◽  

Central venous catheter (CVC) known as standard method for hemodynamic monitoring that plays an essential role in critically ill patient management. After recognizing critical condition, measuring, and evaluating the underlying pathophysiological strategies and receiving suitable therapy


2006 ◽  
Vol 72 (9) ◽  
pp. 833-836 ◽  
Author(s):  
Hoang S. Tran ◽  
Brian J. Burrows ◽  
William A. Zang ◽  
David C. Han

Peripherally inserted central venous catheter (PICC) lines have become a frequently used method of intravenous access for long-term administration of antibiotics, chemotherapy, and parenteral nutrition. Catheter-related complications involving the arterial tree are rare. We report a case of a 25-year-old woman with a history of difficult PICC line placement that presented with an arteriovenous fistula in the left arm. Duplex ultrasound confirmed the diagnosis of a brachial artery-to-brachial vein arteriovenous fistula (AVF), and the patient underwent surgical repair. To our knowledge, this is the first reported case of an AVF resulting from PICC line placement. Correction of AVF is indicated to alleviate symptoms as well as to prevent future complications.


Blood ◽  
2019 ◽  
Vol 133 (8) ◽  
pp. 857-866 ◽  
Author(s):  
Sophie Jones ◽  
Warwick Butt ◽  
Paul Monagle ◽  
Timothy Cain ◽  
Fiona Newall

Abstract Asymptomatic central venous catheter (CVC)–related thrombosis in children varies in incidence from 5% to 69%. The rate of acute and long-term complications, such as postthrombotic syndrome (PTS), from asymptomatic CVC-related thrombosis is unknown. This article reports the outcomes of a prospective study of 189 children in pediatric intensive care that aimed to determine the frequency of asymptomatic CVC-related thrombosis during hospital admission, and the incidence of residual CVC-related thrombosis and clinically significant PTS 2 years later. Risk factors associated with CVC-related thrombosis were also identified. This study is distinct from previous work as children identified to have asymptomatic CVC-related thrombosis were not treated (clinical team kept blinded) and the entire cohort was followed for 2 years to determine the natural history of asymptomatic thrombosis. Ultrasounds of 146 children determined a 21.9% incidence of acute CVC-related thrombosis. Two children were symptomatic. No radiological thrombosis extension or clinical embolization occurred in the 126 children assessed at follow-up. Using 2 recognized PTS scales, clinically significant PTS was reported in 2 children (1 symptomatic, 1 asymptomatic CVC-related thrombosis), however, neither had functional impairment. Cardiac arrest was a risk factor for CVC-related thrombosis during admission and femoral CVC placement was predictive of residual thrombosis 2 years later. This study challenges the notion that critically ill children with asymptomatic CVC-related thrombosis require anticoagulant treatment, as the results demonstrate that the incidence of acute or long-term complications is low. A larger confirmatory study of nontreatment of CVC-related thrombosis in critically ill children is justified.


Infection ◽  
2020 ◽  
Vol 48 (6) ◽  
pp. 955-958
Author(s):  
Lysett Wagner ◽  
Frank Bloos ◽  
Slavena Vylkova

AbstractWe report a case of catheter associated bloodstream infection due to Enterobacter ludwigii with a massive aggregation on the outside surface of a central venous catheter (CVC). The 57 years old patient with a history of spondylodiscitis and Staphylococcus aureus-associated endocarditis was admitted to the intensive care unit for acute cerebral infarction. The patient developed signs of infections and the CVC was removed 11 days after placement. The infectious agent was identified by standard diagnostics to the genus level as belonging to the Enterobacter cloacae complex, and additional molecular testing determined the species as E. ludwigii. The catheter was selected for a study aiming to identify the influence of blood components on the formation of central venous catheter-associated biofilms. In this course a massive biofilm was recognized and is presented here.


2012 ◽  
Vol 20 (6) ◽  
pp. 1072-1080 ◽  
Author(s):  
Daniela Cavalcante de Negri ◽  
Ariane Ferreira Machado Avelar ◽  
Solange Andreoni ◽  
Mavilde da Luz Gonçalvez Pedreira

OBJECTIVE: To identify predisposing factors for peripheral intravenous puncture failure in children. METHODS: Cross-sectional cohort study conducted with 335 children in a pediatric ward of a university hospital after approval of the ethics committee. The Wald Chi-squared, Prevalence Ratio (PR) and backward procedure (p≤0.05) tests were applied. RESULTS: Success of peripheral intravenous puncture was obtained in 300 (89.5%) children and failure in 35 (10.4%). The failure rates were significantly influenced by: presence of clinical history of difficult venous access, malnourishment, previous use of peripherally inserted central venous catheter, previous use of central venous catheter, and history of phlebitis or infiltration. In the multivariate model, being malnourished and having previously been submitted to central venous catheterization were the predisposing factors for the failure. CONCLUSION: The failure rate of 10.4% is similar to that identified in analogous studies and was influenced by characteristics of the children and intravenous therapy. In association with this, malnutrition and previous use of a central venous catheter were the most important variables influencing increase in peripheral intravenous puncture failure.


Blood ◽  
2018 ◽  
Vol 132 (Supplement 1) ◽  
pp. 5025-5025
Author(s):  
Rodrigo Luna-Santiago ◽  
Maria T Bourlon ◽  
Ariel Jasqui-Bucay ◽  
Alan Jasqui-Bucay ◽  
Oscar Manuel Fierro-Angulo ◽  
...  

Abstract Introduction Prostate cancer is the most frequent malignant neoplasm diagnosed in men worldwide. Patients with prostate cancer have higher rates of thrombotic events when compared with other groups of cancer patients; that can be explained because of the presence of multiple risk factors such as age, histopathology, type of therapy, and associated comorbidities. The aim of this study was to determine the risk factors related to development of thrombosis in patients with prostate cancer in a tertiary care center. Methods Retrospective cohort study that included patients ≥18yo diagnosed with prostate cancer at our institution between 2014 and 2017. Univariate and multivariate analysis were performed including all previously described thrombosis risk factors in cancer patients. Results A total of 101 patients were included. Median age was 72 years (52-92). A total of 23 patients (22.8%) presented with a thrombotic event. Regarding baseline characteristics, patients with thrombosis were older (77 vs. 71 years; p=.015), had lower levels of HDL (40.4 vs. 48 mg/dL; p=.033), and a higher prevalence of primary hypertension (65.2% vs.34.6%; p=.009). In patients with thrombosis, 52.2% (n=12) were venous thrombosis and 47.8% (n=11) were arterial. The most common events were pulmonary thromboembolism (n=7; 58.3%) for venous thrombosis and acute coronary syndromes (n=6; 54.5%) for arterial events. In univariate analysis risk factors related to the development of thrombosis were: prostration > 3 days (p=.039), immobility (p=.023), central venous catheter (p=.004), congestive heart failure (p=.021), history of TE (p=.021), major surgery (p=.031) and hip fracture (p=.021). Table 1. On multivariate analysis factors that remained statistically significant were: central venous catheter OR 8.8 (CI 95% 2.2-35.7, p=.002), previous thrombosis OR 10.3 (CI 95% 1.5-72.8, p=.020), and hip fracture OR 8.5 (CI 95% 1.2-63.5,p=.037). Conclusions In conclusion, our study confirms findings from previous studies regarding factors that significantly predispose cancer patients to thrombosis development. Considering our population age, it is not surprising that risk factors in patients with prostate cancer were mainly related to the presence of other comorbiditiesparticularly cardiovascular and atherothrombotic disease. The main risk factor was history of previous thrombosis, suggesting that closer and prolonged anticoagulation therapy should be consider. Multicenter prospective studies most be urged in our population to asses and validate risk factors, and design prognostic scores that can help on determining which patients could be candidates to early intervention modifying preexisting factors and/or receiving prophylactic dose of anticoagulants. Disclosures No relevant conflicts of interest to declare.


2019 ◽  
Vol 21 (4) ◽  
pp. 533-535
Author(s):  
Emily R Hignell ◽  
Julian Phelps

Central venous catheters are widely used in intensive care and critically unwell patients, and reporting of unusual complications is in the interest of those using them on a regular basis. Recognised complications involve vascular, cardiac and pulmonary systems and include the risk of infection. Described is a case with a recurrent complication of device failure secondary to migration of the central venous catheter tip as a result of recurrent coughing episodes. The approach to inserting central catheters and diagnosing the cause for the migration is discussed. This case directly demonstrated looping and significant movement of a polyurethane catheter as a result of coughing. On two occasions, this resulted in the tip migration and the catheter becoming kinked, causing premature failure of the central venous catheter. This has only been seen before with silicone catheters. There should be high index of suspicion for migration of central venous catheters in patients with history of cough. Recommendations include maintaining a high index of suspicion for migration of central venous catheters in patients with history of cough and insertion of larger French size catheters in patient groups prone to severe coughing episodes. Ways to optimise initial central venous catheter placement using intracavitary electrocardiogram should be considered along with the use of interventional radiology in complex cases and those with recurrent complications.


2020 ◽  
Vol 58 (227) ◽  
Author(s):  
Niraj Kumar Keyal ◽  
Sumal Thapa ◽  
Pooja Adhikari ◽  
Sanjeeb Yadav

Malposition of central venous catheter tip inserted into the subclavian and internal jugular vein is a rare unavoidable complication that can be decreased if inserted under ultrasound guidance. We report case series of three patients, two of subclavian and another of internal jugular inserted central venous catheter, in which the catheter malpositioned into ipsilateral internal jugular and subclavian vein respectively but had no effect on patient management. From this, we want to emphasize that the effect of malposition of central venous catheter tip depends upon the indication for which central venous catheter was inserted; it can be detected bedside by ultrasound and flush test.


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