scholarly journals Factors influencing antihypertensive medication adherence among hypertensive patients: A cross-sectional study in two selected Eritrean hospitals

Author(s):  
Idris M Idris ◽  
◽  
Samuel J Wolday ◽  
Brkti Abraham ◽  
Daniel Abraham ◽  
...  

Objective: Hypertension is a major modifiable cause of cardiovascular and cerebrovascular disease affecting more than one billion individuals worldwide. Adherence to recommended antihypertensive medications is central to control hypertension. The purpose of this study was to assess medication adherence and its influencing factors among hypertensive patients in Halibet and Hazhaz Hospitals in Asmara, Eritrea. Methods: Hospital-based cross-sectional study was conducted among 360 hypertensive patients in Halibet and Hazhaz Hospitals of Asmara from February through May 2018. A convenience sampling was used to select study participants. Data related to medication adherence were collected using a structured 8-item Morisky Medication Adherence Scale. Data were analyzed using SPSS version 22. A bivariate and multivariate analysis was done to determine independent predictors of medication adherence among hypertensive patients. Adjusted odds ratio (at 95% CI) and p value < 0.05 was used to assert the effect of the independent variables. Results: Out of 360 patients enrolled in the study, two hundred forty nine (69.2%) had good medication adherence and the remaining 30.8% had poor adherence. The study found that Being female (AOR (95% CI): 1.8 (0.63, 4.85), p<0.05), having Monthly income ≥ 1000 nakfa (AOR (95% CI): 2.85 (0.76, 5.61), , p<0.05), having comorbid disease (AOR (95% CI): 2.7 (0.98, 4.23), p<0.05), family history of hypertension (AOR (95% CI): 2.12 (0.78, 5.76), p <0.05), longer duration of hypertension (AOR (95% CI): 1.32 (0.65, 4.89), p< 0.05), BP < 140/90 mmHg (AOR (95% CI): 2.4 (1.41, 8.73), P<0.05), and taking only one pill per day (AOR (95% CI): 2.7 (0.97, 6.84),P<0.05) were factors significantly influenced good medication adherence. Conclusion: Medication adherence among hypertensive patients was relatively high in this study. Increasing adherence counseling and patient education about the disease and its treatment are important measures to scale-up adherence status of patients.

2020 ◽  
Vol 26 (1) ◽  
Author(s):  
Fahad M. Algabbani ◽  
Aljoharah M. Algabbani

Abstract Background Hypertension is a major risk factor for cardiovascular disease, which is the leading cause of mortality globally. Patient’s adherence to treatment is a cornerstone factor in controlling hypertension and its complications. This study assesses hypertension patients’ adherence to treatment and its associated factors. Methods This cross-sectional study conducted in Riyadh, Saudi Arabia. The study targeted outpatients aged ≥18 years who were diagnosed with hypertension. Participants were recruited using a systemic sampling technique. The two main measurements were assessing adherence rate of antihypertensive medications using Morisky scale and identifying predictors of poor medication adherence among hypertensive patients including socio-economic and demographic data, health status, clinic visits, medication side effects, medications availability, and knowledge. Descriptive and logistic regression analyses were performed to assess factors associated with poor adherence. Results A total of 306 hypertensive outpatients participated in this study. 42.2% of participants were adherent to antihypertensive medications. Almost half of participants (49%) who reported having no comorbidities were adherent to antihypertensive medications compared to participants with one or more than one comorbidities 41, 39% respectively. The presence of comorbid conditions and being on multiple medications were significantly associated with medication adherence (P-values, respectively, < 0.004, < 0.009). Patients with good knowledge about the disease and its complications were seven times more likely to have good adherence to medication (P <  0.001). Conclusions Non-adherence to medications is prevalent among a proportion of hypertensive patients which urges continuous monitoring to medication adherence with special attention to at risks groups of patients. Patients with comorbidities and on multiple medications were at high risk of medication non-adherence. Patients’ knowledge on the disease was one of the main associated factors with non-adherence.


2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
R. Bou Serhal ◽  
P. Salameh ◽  
N. Wakim ◽  
C. Issa ◽  
B. Kassem ◽  
...  

Background. A new Lebanese scale measuring medication adherence considered socioeconomic and cultural factors not taken into account by the eight-item Morisky Medication Adherence Scale (MMAS-8). Objectives were to validate the new adherence scale and its prediction of hypertension control, compared to MMAS-8, and to assess adherence rates and factors. Methodology. A cross-sectional study, including 405 patients, was performed in outpatient cardiology clinics of three hospitals in Beirut. Blood pressure was measured, a questionnaire filled, and sodium intake estimated by a urine test. Logistic regression defined predictors of hypertension control and adherence. Results. 54.9% had controlled hypertension. 82.4% were adherent by the new scale, which showed good internal consistency, adequate questions (KMO coefficient = 0.743), and four factors. It predicted hypertension control (OR = 1.217; p value = 0.003), unlike MMAS-8, but the scores were correlated (ICC average measure = 0.651; p value < 0.001). Stress and smoking predicted nonadherence. Conclusion. This study elaborated a validated, practical, and useful tool measuring adherence to medications in Lebanese hypertensive patients.


2021 ◽  
Vol 12 (2) ◽  
pp. 327
Author(s):  
Ikit Netra Wirakhmi ◽  
Iwan Purnawan

AbstrakLatar belakang: Sampai saat ini, hipertensi masih merupakan tantangan besar di Indonesia. Kepatuhan pasien dalam menggunakan obat berpengaruh terhadap keberhasilan terapi pengobatan. Adanya ketidakpatuhan pasien hipertensi dalam minum obat dapat memberikan efek negative yang sangat besar, seperti munculnya komplikasi. Tujuan: Mengetahui hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi di Puskesmas Karangjambu Kabupaten Purbalingga. Metode: Desain penelitian ini adalah cross sectional study. Responden dalam penelitian ini adalah pasien hipertensi di Puskesmas Karangjambu Kbupaten Purbalingga. Sampel diambil menggunakan teknik accidental sampling dengan jumlah 86 responden. Data dikumpulkan pada bulan Mei 2021 menggunakan kuesioner 8 – Item Morisky Medication Aderence Scale (MMAS – 8) dan pengukuran tekanan darah secara langsung. Hasil: Penelitian ini menunjukkan bahwa Sebagian besar responden adlaah perempuan (86%), sebgain besar berada pada kategori tingkat kepatuhan sedang (47%) dan pada kategori hipertensi tahap 2 (63%). Uji stastistik didapatkan nilai p value 0.901 menunjukkan bahwa tidak ada hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi. Kesimpulan: Tidak ada hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi AbstractBackground: In Indonesia, hypertension is still a major problem. Adherence to treatment is critical for hypertension patients' long-term health and well-being. Adherence are required for hypertension therapy to be effective, and altering these patients' behavior has the greatest potential for improving hypertensive control. Objectives: To explore the relationship between medication adherence and blood pressure in hypertension patients. Methods: We used the cross-sectional study. This research sample was hypertension patients at Karangjambu Health Centre Purbalingga Regency. We included 89 respondents by accidental sampling technique. We collected the data by questionnaire. The Gamma & Sommers’d test was performed to analyze the data. Results: This research showed that that the majority of respondents were women (86%), the moderate category had the highest level of adherence (47%) and the most respondents suffer from hypertension stage 2 (63%). The statistical test result of 0.910 suggested that there was no relationship between medication adherence and blood pressure in hypertensive patients. Conclusions: There was also no significant between medication adherence and blood pressure. 


2021 ◽  
Author(s):  
Zenawi Zeramariam Araia ◽  
Araia Berhane Mesfin ◽  
Amanuel Hadgu Mebrahtu ◽  
Adiam Ghebreyohanns Tewelde ◽  
Randa Osman ◽  
...  

Abstract Background: Both diabetes mellitus (DM) and tuberculosis (TB) are among the leading causes of morbidity and mortality in Eritrea. TB-DM comorbidity is known to complicate TB care, control and prevention. However, systematically studied epidemiological data on TB-DM comorbidity and its associated risk factors is lacking in this country. Objective: This study aimed to assess the prevalence of DM and its associated factors among TB patients in Maekel region, Eritrea.Methods: Analytical cross-sectional study was conducted in eleven TB diagnostic and treatment sites. Pretested data extraction tool was used to collect data from medical records. Prevalence data was analysed using frequencies, proportions and median. To determine DM risk factors, univariable and multivariable logistic regression analysis was done with 95%CI and p value < 0.05 considered significant. Results: Out of total eligible (1,134) TB cases, DM prevalence was 9.88%. Age and BMI were identified as independent risk factors for DM among TB patients. Higher odds of DM was found among TB patients aged 45-54 (aOR: 4.85[1.39-16.94], p= 0.013) and those ≥ 55 (aOR: 6.99[2.12-23.04], p= 0.001). TB cases with normal BMI were two times more likely to have DM (aOR: 2.00[1.23-3.26], p= 0.005) compared to those underweight. Conclusion: The prevalence of DM among TB cases observed in this study is high, a clarion call to scale up current efforts to integrate TB-DM services within routine care. Furthermore, age and BMI were identified as independent risk factors for DM in TB cases, pointing to the need to pay attention to age and BMI status when managing this co-morbidityKey words: TB-DM prevalence, transient hyperglycaemia, fasting blood glucose, pre-diabetes, Eritrea.


2016 ◽  
Vol 1 (2) ◽  
pp. 10-17
Author(s):  
Syahrida Dian Ardhany

Penelitian ini merupakan cross sectional study data diambil selama 1 bulan (November 2015) di poli Penyakit Dalam RSUD dr. Doris Sylvanus Palangka Raya. Pasien hipertensi yang dapat berpartisipasi adalah pasien dengan usia = 18 tahun � 65 tahun. Data diperoleh dengan cara melakukan wawancara menggunakan instrument kuisioner MMAS (Morisky Medication Adherence Scale). Pada penelitian ini subyek yang memenuhi kriteria inklusi sejumlah 86 pasien. Hasil penelitian menunjukkan tingkat kepatuhan minum obat pasien hipertensi di Poli Penyakit Dalam RSUD dr. Doris Sylvanus Palangka Raya adalah tingkat kepatuhan sedang dengan score MMAS= 6,05 � 1,94, selain itu baik usia maupun tingkat pendidikan tidak mempunyai pengaruh terhadap tingkat kepatuhan minum obat, yang dibuktikan dengan hasil uji SPSS menggunakan Kruskal Wallis Test P= 0,806 untuk usia dan P= 0,178 untuk tingkat pendidikan (P < 0,05). Pada penelitian ini dapat disimpulkan bahwa tingkat kepatuhan minum obat pasien hipertensi di poli penyakit dalam RSUD dr. Doris Sylvanus Palangka Raya periode November 2015 adalah tingkat kepatuhan sedang.


Author(s):  
Martin Kampamba ◽  
Farhiyyah Abanur ◽  
Christabel Nang’andu Hikaambo ◽  
Steward Mudenda ◽  
Kennedy Saini ◽  
...  

Background: Medication adherence is the mainstay to good treatment outcomes. Failure to adhere to medication in hypertensive patients may lead to considerable deterioration of the disease resulting in increased costs of healthcare and mortality. Knowledge about the name of the drug, indications and side effects may enhance medication adherence. Therefore, the aim of this study was to assess effects of medication knowledge on medication adherence among hypertensive patients.Methods: This was a cross-sectional study that involved 120 hypertensive patients. A structured questionnaire was used to collect data on demographic characteristics. Adherence was assessed using the 8-item Morisky medication adherence scale while patient’s medication knowledge was assessed using a 7-item scale. Multiple logistic regression was used to assess factors associated with medication adherence.Results: The mean age of participants was 59 years (SD±14.9) and 10 (8.3%), 42 (35%) and 68 (56.7%) had adequate, average and poor medication knowledge respectively. The prevalence of adherence in this study was 37.5%. In multivariable logistic regression analysis, uncontrolled blood pressure (BP) (AOR: 0.38, CI: 0.16-0.90) was associated with lower likelihood of adhering to medication.Conclusions: The adherence level to treatment was low and medication knowledge of hypertensive patients was generally poor. Uncontrolled BP was associated with non-adherence. Patients with uncontrolled hypertension should be given health education and counselling regarding their condition to improve medication adherence. 


2019 ◽  
Vol 5 (3) ◽  
pp. 186-191
Author(s):  
Abrar Wahab ◽  
Md Mahabub Ul Islam ◽  
Mehbuba Mehnoor Laboni ◽  
Anisa Fatema ◽  
Abeda Saleha Renesa ◽  
...  

Rheumatic heart disease (RHD) is a significant public health problem and Non-adherence to treatment is an important and often unrecognized risk factor for cardiovascular mortality. The study aimed to assess self-reported medication adherence by 8-item Morisky Medication Adherence Scale (MMAS-8) among rheumatic heart disease patients and determine the associated factors. A cross-sectional study was carried out by applying a structured interview to Rheumatic heart disease patients aged 18 or higher in a tertiary hospital in Bangladesh. Among Rheumatic heart disease patients, 63.5% showed medium adherence, 36.5% showed low adherence to medication. Walking habit (P= 0.000), exercise habit (P=0.000), smoking habit (P=0.000), and duration of RHD (P=0.005) found significantly associated with medication adherence. Multiple logistic regression analysis also revealed, don't have walking habit more than 10 minutes at a time (AOR=2.416, 95% CI: 1.212-4.816), don't having exercise habit (AOR=2.420, 95% CI: 1.206 – 4.859), don't having habit of smoking (AOR=0.392, 95% CI: 0.183 – 0.841), duration of RHD for less than 15 (AOR=4.190, 95% CI: 0.851 – 20.631) are independent predictors of adherence. Our study demonstrated medium to low medication adherence in the Morisky Medication Adherence Scale among rheumatic heart disease patients. Asian J. Med. Biol. Res. June 2019, 5(3): 186-191


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