scholarly journals Renal Consults from the Oncology Floor

2016 ◽  
Vol 1 (1) ◽  
pp. 5-8
Author(s):  
Mark A. Perazella

Onco-nephrology is a rapidly growing subspecialty area, which was born of the unique kidney disease and cancer connection that exists. In reality, this area of subspecialization combines the knowledge and skills of a number of specialty groups that includes nephrologists, oncologists, urologists, intensivists, pharmacologists, and palliative care specialists. In this inaugural issue of the Journal of Onco-Nephrology, a series of papers addressing the various forms of kidney disease that develop in patients admitted to the oncology floor is presented as part of the Onco-Nephrology Highlights section. These papers are based on a session at the American Society of Nephrology Kidney Week 2015 in San Diego, CA, USA, entitled “Renal Consults from the Oncology Floor.” The editors hope you find these 4 papers educational and practical in your care of patients with cancer and kidney disease.

2020 ◽  
Vol 4 (1-2) ◽  
pp. 26-27
Author(s):  
Mark A Perazella

Onco-nephrology is an important sub-field of nephrology, which interfaces with the fields of oncology, hematology, urology, critical care medicine, clinical pharmacology, and palliative care medicine. The unique connection that exists for kidney disease and cancer in all phases of clinical medicine continues to rapidly expand. Onco-nephrology combines the knowledge and skills of a number of specialty groups that span all areas of clinical medicine. In this issue of the Journal of Onco-Nephrology, a series of papers address the various forms of kidney disease that develop in patients with cancer and its therapy. This Onco-Nephrology Highlights series includes papers that are based on lectures delivered at the American Society of Nephrology Kidney Week Onco-Nephrology Early Program that took place in Washington, DC, in 2019. We hope you find these three papers educational and practical as you evaluate and treat patients with cancer and kidney disease in your clinical practice.


2019 ◽  
Vol 3 (2) ◽  
pp. 88-91
Author(s):  
Mark A Perazella ◽  
Biruh Workeneh ◽  
Sheldon Chen

Over the past decade, Onco-Nephrology has emerged as an important sub-field of not only nephrology and oncology but also hematology, urology, critical care medicine, clinical pharmacology, and palliative care medicine. This nexus reflects the unique connection that exists for kidney disease and cancer in all of clinical medicine. As noted, Onco-Nephrology combines the knowledge and skills of a number of specialty groups that span all areas of medicine. In this issue of the Journal of Onco-Nephrology, a series of papers addressing the various forms of kidney disease that develop in patients with cancer and its therapy is presented as part of the Onco-Nephrology Highlights section. These papers are based on the Onco-Nephrology Symposium that took place at MD Anderson Cancer Center in 2018. We hope you find these six papers educational and practical as you evaluate and treat patients with cancer and kidney disease in your clinical practice.


Author(s):  
J. Pedro Teixeira ◽  
Sara A. Combs

Supportive care of patients with progressive kidney failure, like the care needed by all patients with chronic kidney disease and end-stage kidney disease, is most successfully provided through a multidisciplinary team. An effective kidney supportive care program requires that the multidisciplinary team be properly educated on the palliative needs of these patients and that team members develop primary palliative care skills to meet these needs. This chapter presents the case for why nephrology clinicians need to acquire primary palliative care knowledge and skills to better treat their patients. It reviews the existing state of supportive care for patients with kidney disease and of the training in primary palliative care currently provided to nephrology fellows and nephrologists. It recommends the development of a primary palliative care curriculum for members of the multidisciplinary kidney care team involved in patient care and makes suggestions on curriculum content for nephrology clinicians.


Author(s):  
Myles S. Nickolich ◽  
Areej El-Jawahri ◽  
Jennifer S. Temel ◽  
Thomas W. LeBlanc

Palliative care has received increasing attention at the American Society of Clinical Oncology (ASCO) Annual Meeting since the publication of its provisional clinical opinion on the topic in 2012. Despite frequent discussion, palliative care remains a source of some controversy and confusion in clinical practice, especially concerning who should provide it, what it encompasses, and when and how it can help patients and their families. In this article, we provide a formal definition of palliative care and review the state of the science of palliative care in oncology. Several randomized controlled trials now show that palliative care improves important outcomes for patients with cancer. Related outcome improvements include a reduction in symptoms, improved quality of life, better prognostic understanding, less depressed mood, less aggressive end-of-life care, reduced resource utilization, and even prolonged survival. As such, ASCO recommends early integration of palliative care into comprehensive cancer care for all patients with advanced disease and/or significant symptom burden. Our aim is that this summary will facilitate greater understanding about palliative care and encourage further integration of palliative care services into cancer care. More research is needed to illuminate the mechanisms of action of palliative care and to improve the specificity of palliative care applications to unique scenarios and populations in oncology.


2019 ◽  
Vol 10 (03) ◽  
pp. 123-125
Author(s):  
Claudia Schöllmann

Anfang Dezember fand in San Diego/USA der Jahreskongress der American Society of Hematology (ASH) statt. Traditionell nimmt die Supportivtherapie beim ASH-Kongress eine weniger bedeutende Rolle als etwa beim ASCO-Meeting, das supportiven Themen mittlerweile eigene Sessions widmet. Dennoch gab es beim diesjährigen ASH interessante Neuigkeiten zur Supportivtherapie bei hämatologischen Malignomen, die wir hier schwerpunktmäßig vorstellen. Im Fokus standen die Prophylaxe venöser Thromboembolien, die Vorteile der Eisenchelation bei transfusionspflichtigen Patienten mit MDS sowie das bessere Verständnis der Neurotoxizität beim therapeutischen Einsatz von CAR-T-Zellen.


2021 ◽  
Author(s):  
Maureen Metzger ◽  
Jonathan Yoder ◽  
Kara Fitzgibbon ◽  
Leslie Blackhall ◽  
Emaad Abdel-Rahman

Author(s):  
Nanako Koyama ◽  
Chikako Matsumura ◽  
Yuuna Tahara ◽  
Morito Sako ◽  
Hideo Kurosawa ◽  
...  

Abstract Purpose The aims of the present study were to investigate the symptom clusters in terminally ill patients with cancer using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 15 Palliative Care (EORTC QLQ-C15-PAL), and to examine whether these symptom clusters influenced prognosis. Methods We analyzed data from 130 cancer patients hospitalized in the palliative care unit from June 2018 to December 2019 in an observational study. Principal component analysis was used to detect symptom clusters using the scored date of 14 items in the QLQ-C15-PAL, except for overall QOL, at the time of hospitalization. The influence of the existence of these symptom clusters and Palliative Performance Scale (PPS) on survival was analyzed by Cox proportional hazards regression analysis, and survival curves were compared between the groups with or without existing corresponding symptom clusters using the log-rank test. Results The following symptom clusters were identified: cluster 1 (pain, insomnia, emotional functioning), cluster 2 (dyspnea, appetite loss, fatigue, and nausea), and cluster 3 (physical functioning). Cronbach’s alpha values for the symptom clusters ranged from 0.72 to 0.82. An increased risk of death was significantly associated with the existence of cluster 2 and poor PPS (log-rank test, p = 0.016 and p < 0.001, respectively). Conclusion In terminally ill patients with cancer, three symptom clusters were detected based on QLQ-C15-PAL scores. Poor PPS and the presence of symptom cluster that includes dyspnea, appetite loss, fatigue, and nausea indicated poor prognosis.


Author(s):  
Alycia A. Bristol ◽  
Sobaata Chaudhry ◽  
Dana Assis ◽  
Rebecca Wright ◽  
Derek Moriyama ◽  
...  

Objectives: The ideal clinical model to deliver palliative care to patients with advanced kidney disease is currently unknown. Internationally, ambulatory kidney palliative care clinics have emerged with positive outcomes, yet there is limited data from the United States (US). In this exploratory study we report perceptions of a US-based ambulatory kidney palliative care clinic from the perspective of patient and caregiver attendees. The objective of this study was to inform further improvement of our clinical program. Methods: Semi-structured interviews were conducted to elicit the patient and caregiver experience. Eleven interviews (8 patients with chronic kidney disease stage IV or V and 3 caregivers) were analyzed using qualitative description design. Results: We identified 2 themes: “Communication addressing the emotional and physical aspects of disease” and “Filling gaps in care”; Subthemes include perceived value in symptom management, assistance with coping with disease, engagement in advance care planning, program satisfaction and patient activation. Significance of Results: Qualitative analysis showed that attendees of an ambulatory kidney palliative care clinic found the clinic enhanced the management of their kidney disease and provided services that filled current gaps in their care. Shared experiences highlight the significant challenges of life with kidney disease and the possible benefits of palliative care for this population. Further study to determine the optimal model of care for kidney palliative care is needed. Inclusion of the patient and caregiver perspective will be essential in this development.


2021 ◽  
pp. bmjspcare-2020-002638
Author(s):  
Juan Yang ◽  
Dietlind L Wahner-Roedler ◽  
Xuan Zhou ◽  
Lesley A Johnson ◽  
Alex Do ◽  
...  

BackgroundPain is one of the most common and problematic symptoms encountered by patients with cancer. Due to the multifactorial aetiology, pain management of these patients frequently requires multidisciplinary interventions including conventional support and specialty palliative care. Acupuncture has been identified as a possible adjunctive therapy for symptom management in cancer pain, and there is currently no systematic review focused solely on the evidence of acupuncture on cancer pain in palliative care.ObjectiveTo critically analyse currently available publications regarding the use of acupuncture for pain management among patients with cancer in palliative care settings.MethodsMultiple academic databases were searched from inception to 29 October 2020. Randomised controlled trials involving acupuncture in palliative care for treatment of cancer-related pain were synthesised. Data were extracted by two independent reviewers, and methodological quality of each included study was assessed using the Oxford Centre for Evidence-Based Medicine (OCEBM) 2011 Levels of Evidence.ResultsFive studies (n=189) were included in this systematic review. Results indicated a favourable effect of acupuncture on pain relief in palliative care for patients with cancer. According to OCEBM 2011 Levels of Evidence, they were level 2 in one case (20%), level 3 in two cases (40%) and level 4 in the remaining (40%). Low-level evidence adversely affects the reliability of findings.ConclusionsAcupuncture may be an effective and safe treatment associated with pain reduction in the palliative care of patients with cancer. Further high-quality, adequately powered studies are needed in the future.


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