IMPACT OF HIRDOTHERAPY ON VEGETATIVE DIS-ABILITIES AFTER CORONAVIRUS INFECTION

2021 ◽  
pp. 8-12
Author(s):  
С.Ж. СЕРИКБАЕВА ◽  
Н.Ж. ОРМАНОВ
Keyword(s):  
Neuropsychological Testing ◽  
Climatic Conditions ◽  
Emotional Disturbances ◽  
Predominant Frequency ◽  
Hyperventilation Syndrome ◽  
Coronavirus Infection ◽  
Index Of Severity ◽  
Autonomic Disturbances ◽  
Calf Pain ◽  
Objective Improvement

Вегетативно сосудистые и вегетативнотрофические изменения наблюдались у абсолютного большинства пациентов с ПКВИ с преобладанием частоты эмоциональных нарушений (страха смерти) 100%, генерализованный гипергидроз у 75,9%, наличие гипервентиляционного синдрома 71%, субфебрилитет, наличие вегетососудистых кризов, мигрени, склонности к обморокам 50,6%, боли в икроножных мыщах 48,1%, чувствительность к перемене климатических условий при ПКВИ наличие ухудшения самочувствия при смене погоды у 48,1% пациентов. Дисдинамические и дизритмические расстройства лабильности артериального давления (АД) с тенденцией к повышению и сердечного ритма с тенденцией к тахикардии 46,9% больных с ПКВИ. Под влиянием пятикратной и десятикратной применение грудотерапии обшое количество баллов симптомов вегетативных расстройств после перенесенной КВИ составили 557 баллов и 31 баллов и снизились на 82,4% и 99,1%. Индекс выраженности вегетативных нарушении сизились от 2,23±0,11 условных единиц (уе) на 0,39±0,01 и 0,02±0,001 уе.Результаты нейропсихологического тестирования у больных, принимавших гирудотерапии, показали объективное улучшение у них вегатативных нарушении, средний балл индекс выраженности вегетативных нарушении достоверно снизился после пятикратного и 10 дненого применение на 82,6% и 99,1% (р < 0,001) по сравнению с фоновым показателем.Таким образом, у больных с ПКВИ, принимавших 10 дневный курс гирудотерапии, показали объективное улучшение у них вегатативных функций. Autonomic vascular and autonomictrophic changes were observed in the vast majority of patients with PCVI with a predominant frequency of emotional disturbances (fear of death) 100%, generalized hyperhidrosis in 75.9%, the presence of hyperventilation syndrome 71% , subfebrile, presence of vegetovascular crises, migraine, tendency to fainting 50.6% , calf pain 48.1% , sensitivity to changes in climatic conditions in PCVI presence of worsening of wellbeing at a change of weather in 48.1% patients. Dysdynamic and dysrhythmic disorders of arterial pressure (BP) lability with a tendency to increase and cardiac rhythm with a tendency to tachycardia 46.9% of patients with PKVI. Under the influence of fivefold and tenfold application of chest therapy, the total score of symptoms of autonomic disorders after CPVI was 557 and 31 and decreased by 82.4% and 99.1%, respectively. The index of severity of autonomic disturbances sized up from 2.23±0.11 conventional units (ue) by 0.39±0.01 and 0.02±0.001 ue.The results of neuropsychological testing in the patients who took hirudotherapy showed the objective improvement of vegetative disturbances in them, the average index score of vegetative disturbances expression reliably decreased after 5 and 10 day application by 82,6 % and 99,1 % (p <0,001) in comparison with the background index.Thus, patients with PKVI who underwent hirudotherapy for 10 days showed objective improvement of vegetative functions.

scholarly journals Cough in the post COVID period: clinical examples

2021 ◽  
Vol 31 (3) ◽  
pp. 375-382
Author(s):  
O. V. Fesenko
Keyword(s):  
Post Infection ◽  
Spontaneous Pneumothorax ◽  
Protective Factor ◽  
Respiratory Control ◽  
Hyperventilation Syndrome ◽  
Chronic Lung Diseases ◽  
Wide Range ◽  
Coronavirus Infection ◽  
Mechanisms Of Development ◽  
Traction Bronchiectasis

Among the extensive list of manifestations of post COVID syndrome, cough is often found. Most researchers interpret its character as post infection. In some patients, post infection cough becomes productive, and combined mucoactive therapy is required for effective treatment. Since the onset of the pandemic, clinical descriptions of spontaneous pneumothorax have accumulated in the literature. The risk of this complication is present even in patients who are not burdened with chronic lung diseases, as well as those who are breathing spontaneously. The study of the mechanisms of development of spontaneous pneumothorax in COVID-19 is necessary for the development of further therapeutic and preventive measures. Traction bronchiectasis occurs in 27 – 52.5% of cases of new coronavirus infection. Changes in the structure of the bronchi predispose to chronic cough and recurrent infections. Respiratory viral infection has been considered in the past as a trigger for bronchial asthma. There is controversy over the new coronavirus. Asthma has been suggested as a protective factor in COVID-19, due to the specific inflammation profile that protects patients. In some patients who have had COVID-19, the cough is due to hyperventilation syndrome. To explain it, a hypothesis of impaired respiratory control was proposed. The paper presents clinical examples illustrating a wide range of pathological conditions accompanied by cough. Possible relationships between cough and previous coronavirus infection are discussed.

Central Nervous System Tumors

2021 ◽  
pp. 221-225
Author(s):  
Alan D. Valentine
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Differential Diagnosis ◽  
Radiation Therapy ◽  
Neuropsychological Testing ◽  
Emotional Disturbances ◽  
Central Nervous System Tumors ◽  
Nervous System Tumors ◽  
Cns Cancer ◽  
Cns Neoplasms

This chapter provides an overview of behavioral presentations of central nervous system (CNS) neoplasms in adults. Epidemiology of CNS tumors is briefly reviewed. Complications including cognitive dysfunction and emotional disturbances including mood disorders, anxiety, and psychosis are described. The behavioral adverse effects of treatments for CNS cancer, including radiation therapy and steroids, are discussed. The chapter reviews the differential diagnosis of behavioral presentations in this setting as well as an approach to workup and treatment, including neuropsychological testing, psychotherapy, and pharmacotherapy. The potential effects of CNS cancer on caregivers and staff, and possible assistance for them, are covered.

Generalized form and duration of myasthenia gravis as predictors of cognitive impairment

2020 ◽  
pp. 60-64
Author(s):  
S. A. Nalkin ◽  
M. G. Sokolova ◽  
S. V. Lobzin ◽  
V. L. Kokorenko ◽  
N. V. Vasileva ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Myasthenia Gravis ◽  
Memory Impairment ◽  
Disease Duration ◽  
Neuropsychological Testing ◽  
Emotional Disturbances ◽  
Control Group ◽  
Laboratory Examination ◽  
History Of ◽  
Reliable Correlation

We performed a clinical, neurological, neuropsychological and laboratory examination of 30 patients with a confirmed diagnosis of myasthenia gravis, aged 25 to 69 years (49.0 ± 14.6 years), 11 men and 19 women. Among the examined patients, the generalized form of myasthenia was diagnosed in 20 (66.7%) patients: 4 (20.0%) cases of severe and 16 (80.0%) of moderate forms. The ocular form of myasthenia was found in 10 (33.3%) cases. Neuropsychological testing revealed memory impairment in 15 (50.0%), attention – 11 (36.7%), emotional disturbances – 13 (43.3%) patients with myasthenia gravis. A significant decrease in the concentration of brain-derived neurotrophic factor (BDNF) in the blood serum of patients with myasthenia was noted, compared with the control group (p < 0.01). When comparing the data of neuropsychological testing, the level of BDNF and the history of the disease, it was found that patients with a generalized form of myasthenia gravis and a disease duration of more than three years have a lower level BDNF, which has a reliable correlation with lower cognitive function scores.

scholarly journals Post-coronavirus disease 2019 polyneuropathy with significant response to immunoglobulin therapy: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
A. Saleh ◽  
R. Jung ◽  
S. Tonner ◽  
F. Hornof ◽  
M. Strittmatter
Keyword(s):  
Immunoglobulin Therapy ◽  
Term Therapy ◽  
The Novel ◽  
Case Presentation ◽  
Autonomic Disturbances ◽  
Electrophysiological Examination ◽  
Long Term Therapy ◽  
Peripheral Sensory ◽  
Objective Improvement

Abstract Background The symptoms of coronavirus disease 2019, caused by the novel severe acute respiratory syndrome coronavirus 2, were originally assumed to be mainly respiratory. With increasing knowledge, however, it turned out that the spectrum of complaints varies broadly with age and concomitant diseases. While many neurological symptoms were reported in the context of the disease, ranging from permanent fatigue to recurrent headaches and concentration disturbance, treatment approaches are still in development. This case discusses a possible treatment approach with immunoglobulin therapy and its outcomes. Case presentation We present the case of a 56-year-old Caucasian female patient who, following coronavirus disease 2019, developed peripheral sensory and autonomic disturbances that fell within subacute demyelinating neuropathy. Because a significant improvement in symptoms as well as in the results of clinical and electrophysiological examination was reported after immunoglobulin therapy, long-term therapy does not appear to be necessary. Conclusion Given the significant subjective and objective improvement reported, this case provides additional evidence that immunoglobulin therapy can be considered in post-coronavirus disease 2019 syndrome.

EFFECT OF HIRUDOTHERAPY ON INSOMNIA DISORDERS AFTER A CORONAVIRUS INFECTION

2021 ◽  
pp. 48-51
Author(s):  
С.Ж. СЕРИКБАЕВА ◽  
Г.С. КАЙШИБАЕВА ◽  
Г.Б. АБАСОВА
Keyword(s):  
Sleep Quality ◽  
Epworth Sleepiness Scale ◽  
Severity Index ◽  
Average Score ◽  
Insomnia Severity Index ◽  
Average Value ◽  
Coronavirus Infection ◽  
Insomnia Severity ◽  
Objective Improvement

Индекс выраженности бессонницы (ISI) у больных после перенесенной коронавирусной инфекции составили 17,5±1,05, при норме 5,4±0,21, значение шкалы сонливости по Эпворту (ESS) 11,8±0,59 при норме 4,2±0,19 баллов. Индекс качества сна (PSQI), уменьшился и средний балл после пятикратного и 10дневного применения на 24,6 % и 46,5 % (р < 0,001), среднее значение по шкале оценки индекса выраженности бессонницы (ISI) и сонливости по Эпворту (ESS) у больных с ПКВИ уменьшилось после применения 10дневного курса гирудотерапии на 50,9 % и 42,4 %.Индекс выраженности инсомнических нарушений после пятикратного и 10дневного применения гирудотерапии снизились на 24,5% и 47% по сравнеию с исходными даннымиТаким образом, у больных с ПКВИ, принимавших 10дневный курс гирудотерапии, показали объективное улучшение у них инсомнических функций. The insomnia severity index (ISI) in patients after coronavirus infection was 17.5±1.05, with a norm of 5.4±0.21, the Epworth sleepiness scale (ESS) value was 11.8±0.59 with a norm of 4.2±0.19. The index of sleep quality (PSQI), the average score after 5day and 10day course of hirudotherapy decreased by 24,6% and 46,5% (p < 0,001), the average value of the insomnia severity index (ISI) and the Epworth sleepiness scale (ESS) in patients with PCVI decreased by 50,9% and 42,4% after 10day course of hirudotherapy.The index of insomnia disorders expression after 5 and 10day hirudotherapy decreased by 24,5% and 47% in comparison with the initial data.Thus, patients with PKVI who underwent hirudotherapy for 10 days showed objective improvement of insomniac functions.

Neuropsychological Deficits in the Prodromal Phase and Course of an Early-Onset Schizophrenia

2014 ◽  
Vol 42 (3) ◽  
pp. 167-176 ◽  
Author(s):  
Vanessa Puetz ◽  
Thomas Günther ◽  
Berrak Kahraman-Lanzerath ◽  
Beate Herpertz-Dahlmann ◽  
Kerstin Konrad
Keyword(s):  
Verbal Memory ◽  
Early Onset ◽  
Neuropsychological Functioning ◽  
Neuropsychological Testing ◽  
Clinical Situation ◽  
Adolescent Male ◽  
Antipsychotic Treatment ◽  
Early Onset Schizophrenia ◽  
Prodromal Phase ◽  
Illness Onset

Objectives: Although clear advances have been achieved in the study of early-onset schizophrenia (EOS), little is known to date about premorbid and prodromal neuropsychological functioning in EOS. Method: Here, we report on a case of an adolescent male with EOS who underwent neuropsychological testing before and after illness onset. Results: Marked cognitive deficits in the domains of attention, set-shifting, and verbal memory were present both pre-onset and during the course of schizophrenia, though only deficits in verbal memory persisted after illness-onset and antipsychotic treatment. Conclusion: The findings of this case study suggest that impairments in the verbal memory domain are particularly prominent symptoms of cognitive impairment in prodromal EOS and persist in the course of the disorder, which further demonstrates the difficult clinical situation of adequate schooling opportunities for adolescent patients with EOS.

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