scholarly journals Comparison of Anti-inflammatory Activities among Ethanol Extracts of Sophora flavescens, Glycyrrhiza uralensis and Dictamnus dasycarpus, and their Mixtures in RAW 246.7 Murine Macrophages

2014 ◽  
Vol 24 (3) ◽  
pp. 329-335 ◽  
Author(s):  
Min Ho Han ◽  
Moon Hee Lee ◽  
Su Hyun Hong ◽  
Yung Hyun Choi ◽  
Ju Sung Moon ◽  
...  
Keyword(s):  
Glycyrrhiza Uralensis ◽  
Sophora Flavescens ◽  
Murine Macrophages ◽  
Anti Inflammatory ◽  
Ethanol Extracts

Hexane/ethanol extract of Glycyrrhiza uralensis licorice exerts potent anti-inflammatory effects in murine macrophages and in mouse skin

2010 ◽  
Vol 121 (4) ◽  
pp. 959-966 ◽  
Author(s):  
Han Jin Cho ◽  
Soon Sung Lim ◽  
Yeon Sil Lee ◽  
Jong-Sang Kim ◽  
Choong Hwan Lee ◽  
...  
Keyword(s):  
Mouse Skin ◽  
Ethanol Extract ◽  
Glycyrrhiza Uralensis ◽  
Murine Macrophages ◽  
Anti Inflammatory

scholarly journals Antioxidant, Anti-inflammatory, and Antiproliferative Activity of Mori Cortex Radicis Extracts

2020 ◽  
Vol 15 (1) ◽  
pp. 1934578X1989976 ◽  
Author(s):  
Al B. Bayazid ◽  
Jae G. Kim ◽  
Seo H. Park ◽  
Beong O. Lim
Keyword(s):  
Inflammatory Responses ◽  
Antioxidant Activities ◽  
Folk Medicine ◽  
Mitogen Activated Protein Kinase ◽  
Total Phenolic ◽  
Murine Macrophages ◽  
Mitogen Activated Protein ◽  
Anti Inflammatory ◽  
Mori Cortex Radicis ◽  
Ethanol Extracts

Mori Cortex Radicis (MCR) is a well-known Korean and Chinese folk medicine with anti-obesity, anti-inflammatory, anti-asthmatic, and hypoglycemic activities. This study was aimed to evaluate the total phenolic and flavonoid contents, as well as intracellular antioxidant and anti-inflammatory effects of water and 70% (v/v) ethanol extracts of MCR. The antioxidant activities of MCR extracts were determined with diphenyl-2-picrylhydrazyl and 2,2′-azinobis[3-ethylbenzothiazoline-6-sulfonic] scavenging activity assays. The suppressive activities of MCR extracts on the production of nitric oxide (NO*) and the expression of cytokines, c-Fos, activated p38-Mitogen-activated protein kinase (MAPK), and Nuclear factor Kappa B (NF-κB) and splenocytes proliferation in lipopolysaccharide-treated macrophages were determined. Furthermore, this study demonstrated the effects of MCR on reactive oxygen species production in murine macrophages. Mori Cortex Radicis restored deoxyribonucleic acid damages at higher concentrations of the extracts and significantly suppressed free radicals and NO* production. In this study, MCR significantly restored inflammatory responses and intracellular antioxidant activities in murine macrophages (RAW 264.7), which anticipated that MCR could be used as a natural anti-inflammatory agent.

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