scholarly journals Evaluation of the potential effect of Allium sativum, Momordica charantia, Eugenia jambolana, Ocimum sanctum and Psidium guajava on intestinal P-glycoprotein in rats

2017 ◽  
Vol 6 (1) ◽  
pp. 68 ◽  
Author(s):  
Devendra Kumar ◽  
Neerja Trivedi ◽  
Rakesh Dixit
2018 ◽  
Vol 2 (1) ◽  
pp. 24
Author(s):  
Anu Chandra ◽  
Ravjit Sabharwal ◽  
Ramesh Chander ◽  
Farzana Mahdi ◽  
Abbas Ali Mahdi

<p><strong>Background:</strong> Diabetes is one of the commonest and serious metabolic disorders. Much of the morbidity and mortality associated with diabetes is primarily attributed to sequelae requelac of microvascular and macrovascular changes, in which diabetic dyslipidemia is one of the many modifiable risk factors for coronary artery disease, stroke and peripheral vascular disease.</p><p><strong>Objectives:</strong> The main aim of this study was to evaluate the hypoglycemic and antidyslipidemic effect of selected Indian plants in streptozotocin induced diabetic rats.</p><p><strong>Material and Methods:</strong> Azadirachta indica and Ocimm sanctum leaves, Allium sativum bulbs and Momordica charantia fruits were collected, identified taxonomically and extract was obtained. Male Albino rats was used and divided into 8 groups, each consisting of 6 animals, one group act as a control. Diabetes in rats was induced with streptozotocin. Blood samples were collected and biochemical analysis was done for blood sugar, lipid peroxide and lipid profile. The diabetic group without drug treatment was compared with the control, and diabetic plus drug-treated groups were compared with the diabetic group without drug treatment. Data were analyzed using Student ‘t’ test.</p><p><strong>Results:</strong> Our results revealed that administration of streptozotocin in rats caused increase in the levels of glucose, lipid peroxides, cholesterol and triglycerides with lessening of the HDL-cholesterol. Treatment with aqueous extracts of Momordica charantia, Allium sativum, Azadirachta indica and Ocimum sanctum not only reduced the level of blood glucose but also caused lowering of total cholesterol and triglycerides following an increase in the level of HDL-cholesterol.</p><p><strong>Conclusion:</strong> We concluded that the herbal plants tested possess both hypoglycemic and antidyslipidemic activities and their use as a therapeutic tool in diabetes related complications encourage further investigation in this field.</p>


2016 ◽  
Vol 13 (1) ◽  
pp. 21
Author(s):  
THIAGO COSTA FERREIRA ◽  
Ana Lúcia Araújo Cunha ◽  
Élida Barbosa Corrêa

<p>A utilização de espécies vegetais como fungicidas naturais é uma promissora medida para o controle de patógenos veiculados às sementes. Sementes de amendoim têm elevada suscetibilidade ao ataque de fungos habitantes do solo. Devido à importância da cultura do amendoim, o objetivo do trabalho foi avaliar o efeito de extratos vegetais no controle de patógenos veiculados às sementes. Para tanto, foram utilizados extratos de alho (<em>Allium sativum</em>), carambola (<em>Averrhoa carambola</em>), eucalipto (<em>Eucaliptus </em>sp.), goiaba (<em>Psidium guajava</em>), mamona (<em>Ricinus communis</em>), melão-de-São-Caetano (<em>Momordica charantia</em>), mororó (<em>Bauhinia cheilanta</em>), mulungu (<em>Erythrina mulungu</em>), pinhão-manso (<em>Jatropha curcas</em>) e pitanga (<em>Eugenia uniflora</em>). Os extratos foram testados no tratamento de sementes e na avaliação do efeito fungitóxico sobre os patógenos <em>Aspergillus flavus, Aspergillus niger </em>e <em>Penicillium </em>sp<em>.</em> A aplicação dos extratos vegetais diminuiu a incidência fúngica nas sementes, sendo os extratos alcoólicos de goiaba, melão-de-São-Caetano e mamona, na concentração de 100%, os mais efetivos. Os extratos vegetais alcoólicos testados mostraram efeito fungitóxico sobre os patógenos <em>A. flavus, A. niger e Penicillium </em>sp<em>. </em>Conclui-se que os extratos de goiaba, mamona e melão-de-São-Caetano são potenciais ferramentas para serem utilizadas no controle de patógenos veiculados às sementes.</p>


2020 ◽  
Vol 72 (3) ◽  
pp. 285-295 ◽  
Author(s):  
A. Boutasknit ◽  
M. Anli ◽  
A. Tahiri ◽  
A. Raklami ◽  
M. Ait-El-Mokhtar ◽  
...  

2012 ◽  
Vol 23 (1) ◽  
pp. 76-84 ◽  
Author(s):  
Pornsiri Pitchakarn ◽  
Shinobu Ohnuma ◽  
Komsak Pintha ◽  
Wilart Pompimon ◽  
Suresh V. Ambudkar ◽  
...  

2014 ◽  
Vol 23 (1) ◽  
pp. 53-60 ◽  
Author(s):  
MA Bashar ◽  
Mina Chakma

Seven soil fungi viz. Aspergillus flavus, A. fumigatus, A. niger, A. terreus, Penicillium sp., Trichoderma harzianum and T. viride associated with the rhizosphere, non?rhizosphere and rhizoplane of brinjal plants were selected to observe their antagonistic potential against the test fungi Fusarium oxysporum and F. solani . Out of seven soil fungi T. harzianum was found most effective to control the growth of both the test fungi. Plant parts extract of Allium sativum, Asparagus racemosus, Azadirachta indica, Cassia alata, Ocimum sanctum, Zingiber officinale and Datura metel were evaluated for their in vitro efficacy at 5, 10 and 20% concentration against the test fungi. Datura metel, and C. alata and A. indica was found most efficient inhibitor of F. solani and F. oxysporum, respectively. Five fungicides viz., agridazim 50 wp, cozeb 80 wp, newban 50 wp, sunvit 50 wp and vitavax 200 B were evaluated for their in vitro efficacy at 500 ppm concentration against F. solani and F. oxysporum. Vitavax 200B was found most efficient inhibitor of both the test fungi. DOI: http://dx.doi.org/10.3329/dujbs.v23i1.19826 Dhaka Univ. J. Biol. Sci. 23(1): 53-60, 2014


Sign in / Sign up

Export Citation Format

Share Document