Association Between Short Sleep and Body Mass Index, Hypertension Among Acute Coronary Syndrome Patients in Coronary Care Unit

The goal of this study was to evaluate the influence of obstructive sleep apnoea on the severity and short-term prognosis of patients admitted for acute coronary syndrome.Obstructive sleep apnoea was defined as an apnoea–hypopnoea index (AHI) >15 h−1. We evaluated the acute coronary syndrome severity (ejection fraction, Killip class, number of diseased vessels, and plasma peak troponin) and short-term prognosis (length of hospitalisation, complications and mortality).We included 213 patients with obstructive sleep apnoea (mean±sd AHI 30±14 h−1, 61±10 years, 80% males) and 218 controls (AHI 6±4 h−1, 57±12 years, 82% males). Patients with obstructive sleep apnoea exhibited a higher prevalence of systemic hypertension (55% versus 37%, p<0.001), higher body mass index (29±4 kg·m−2versus 26±4 kg·m−2, p<0.001), and lower percentage of smokers (61% versus 71%, p=0.04). After adjusting for smoking, age, body mass index and hypertension, the plasma peak troponin levels were significantly elevated in the obstructive sleep apnoea group (831±908 ng·L−1versus 987±884 ng·L−1, p=0.03) and higher AHI severity was associated with an increased number of diseased vessels (p=0.04). The mean length of stay in the coronary care unit was higher in the obstructive sleep apnoea group (p=0.03).This study indicates that obstructive sleep apnoea is related to an increase in the peak plasma troponin levels, number of diseased vessels, and length of stay in the coronary care unit.

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Impact of creating a hemodynamics room, a coronary care unit, and a primary angioplasty program on the prognosis of acute coronary syndrome in a district hospital

Revista Clínica Española (English Edition) ◽

10.1016/j.rceng.2019.11.017 ◽

2021 ◽

Author(s):

M.N. Solís-Marquínez ◽

J.J. Rondán-Murillo ◽

M. Pérez-Otero ◽

J.M. Vegas-Valle ◽

Í. Lozano Martínez-Luengas ◽

...

Keyword(s):

Acute Coronary Syndrome ◽

Coronary Care Unit ◽

District Hospital ◽

Primary Angioplasty ◽

Coronary Syndrome ◽

Coronary Care

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Body Mass Index and Waist Circumference as Predictive Factors in the Development of Acute Coronary Syndrome in Young Adults

International Journal of Cardiology ◽

10.1016/j.ijcard.2017.09.132 ◽

2017 ◽

Vol 249 ◽

pp. S37

Author(s):

R.E.F. Raja Shariff ◽

N. Chua ◽

R.N. Khir ◽

K.S. Ibrahim ◽

M.K. Mohd Arshad ◽

...

Keyword(s):

Body Mass Index ◽

Acute Coronary Syndrome ◽

Young Adults ◽

Waist Circumference ◽

Body Mass ◽

Predictive Factors ◽

Coronary Syndrome

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Impact of Low Body Mass Index on Features of Coronary Culprit Plaques and Outcomes in Patients With Acute Coronary Syndrome

The American Journal of Cardiology ◽

10.1016/j.amjcard.2021.07.041 ◽

2021 ◽

Author(s):

Nobuaki Kobayashi ◽

Yusaku Shibata ◽

Osamu Kurihara ◽

Takahiro Todoroki ◽

Masayuki Tsutsumi ◽

...

Keyword(s):

Body Mass Index ◽

Acute Coronary Syndrome ◽

Body Mass ◽

Coronary Syndrome ◽

Low Body Mass Index

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The simplified acute physiology score (SAPS) 11 used in the evaluation of outcome in patients with acute coronary syndrome admitted at the coronary care unit

Atherosclerosis Supplements ◽

10.1016/s1567-5688(02)80441-x ◽

2002 ◽

Vol 3 (2) ◽

pp. 160

Keyword(s):

Acute Coronary Syndrome ◽

Coronary Care Unit ◽

Simplified Acute Physiology Score ◽

Acute Physiology Score ◽

Coronary Syndrome ◽

Coronary Care

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The Reduction of Cardiac Patients in the Coronary Care Unit of the Santa Izabel Hospital During the COVID-19 Pandemic

Revista Científica Hospital Santa Izabel ◽

10.35753/rchsi.v4i3-4.180 ◽

2021 ◽

Vol 4 (3/4) ◽

pp. 131-134

Author(s):

Gilson Feitosa ◽

Leandro Cavalcanti ◽

Amanda Fraga ◽

Milana Prado ◽

Gilson Feitosa Filho ◽

...

Keyword(s):

Myocardial Infarction ◽

Acute Coronary Syndrome ◽

Angina Pectoris ◽

Coronary Care Unit ◽

Myocardial Revascularization ◽

St Elevation Myocardial Infarction ◽

Coronary Syndrome ◽

The World ◽

St Elevation ◽

Coronary Care

The coronary care unit by Santa Izabel Hospital (Salvador, Bahia, Brazil) made a comparison of admitted patients with coronary disease cases admitted between two equivalent periods ranging from April through July in 2019 and 2020. There was a striking reduction in 2020 of cases of ST-elevation myocardial infarction (39%); non-ST elevation myocardial infarction (19%); and unstable angina pectoris (21%). This occurred in parallel with what happened in many parts of the world and hampered offering the best treatment strategy to these patients with an acute coronary syndrome such as invasive stratification and myocardial revascularization.

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Abstract 3147: Uric Acid Independently Predicted Acute Coronary Syndrome in a Large Cohort of Ethnic Chinese

Circulation ◽

10.1161/circ.118.suppl_18.s_1103 ◽

2008 ◽

Vol 118 (suppl_18) ◽

Author(s):

Shao-Yuan Chuang ◽

Jonathan Jiunn-Horng Chen ◽

Chih-Cheng Wu ◽

Wen-Harn Pan

Keyword(s):

Body Mass Index ◽

Acute Coronary Syndrome ◽

Uric Acid ◽

Total Cholesterol ◽

Body Mass ◽

Ethnic Chinese ◽

Coronary Syndrome ◽

Group 4 ◽

Group 3 ◽

Group 2

Few studies examine the association between serum uric acid (SUA) and acute coronary syndrome (ACS). We aimed to investigate the association between SUA and ACS in a prospective study of ethnic Chinese. Enrolled were 128569 adults ≥ 20 yrs from 4 MJ Health Checkup Clinics in Taiwan during 1994 –1996, excluding those with heart disease, stroke, renal disease and cancer disease. All physical examination, biochemical test and structured questionnaire were executed in standardized central labs. ACS was defined by main ICD-9 of 410 – 414 from claim data of National Health Insurance for hospitalization and from Death certification registry. Cox proportional hazard model was used to estimate the hazard ratios (HRs) between levels of SUA and ACS events. A total of 2049 subjects (Men: 1239/Women: 810) developed ACS during the period from baseline to Dec.31.2002. Men had higher ACS incidence than women (2.84 vs. 1.61 per 1000 person-years [PY]; p < .0001). Independent risk factors of ACS unfolded from this study included age, male sex, waist circumference, body mass index, triglycerides, total-cholesterol, hypertension, diabetes, uric acid, and current smoking. The crude incidences of ACS were 1.27, 2.06, 3.27 and 4.61 per 1000 PY in that order for four consecutive SUA groups (group1: <5.0 mg/dl; group 2: 5.0 – 6.9 mg/dl; group 3: 7.0 – 8.9 mg/dl; group 4: ≥9.0 mg/dl) (p-value for trend <.0001). Compared to group1, the multi-variate adjusted HRs (95% Confidence intervals) were 1.14 (0.92, 1.42) for group 2, 1.38 (1.10, 1.72) for group 3 and 1.38 (1.10, 1.72) for group 4 among men, and 1.03 (0.87, 1.22), 1.30 (1.05, 1.62) and 1.43 (0.99, 2.05) among women after adjusting for age, systolic/diastolic BP, body mass index, triglycerides, total cholesterol, diabetes, smoking, alcohol drinking, physical activity, and occupation. One standard deviation increase in SUA corresponded to around 30% ACS risk increase in women (HR=1.33; 1.04 –1.70) and 60% in men (HR=1.59; 1.25–2.03). Baseline SUA level independently predicts the development of ACS and should be considered as a potential risk factor of ACS.

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