scholarly journals Chromatographic Methods for Coffee Analysis: A Review

2017 ◽  
Vol 6 (4) ◽  
pp. 60 ◽  
Author(s):  
Alexander Yashin ◽  
Yakov Yashin ◽  
Xiaoyan Xia ◽  
Boris Nemzer

Coffee has been one of the most commercialized food products and most widely researched beverage in the world for decades. It is considered a functional food, primarily due to its high content of compounds that exert antioxidant and other beneficial biological properties. This review summarized the data from analysis of coffee components, both volatile constituents and non-volatile high-molecular weight compounds performed by various chromatographic methods. A list of compounds identified by gas chromatography with mass spectrometry which define the aroma of coffee is provided. Publications on the measurement of methylxanthines (caffeine, theobromine, and theophylline), chlorogenic acids, diterpenes, sugars, amino acids, gamma-aminobutyric acid, dibasic acids, anions, and other compounds by HPLC and UHPLC-MS are reviewed. An overview of publications on the determination of organic contamination in coffee (PAHs, acrylamides, mycotoxins, etc.) and ways to reduce contamination through production technology and brewing methods are presented. Finally, an overview of the literature on authentication assessment for different grades of coffee grown in different regions is provided.

2019 ◽  
Vol 15 (4) ◽  
pp. 312-318
Author(s):  
Shuoye Yang

Background: The therapeutic ability and application of antifungal peptide (APs) are limited by their physico-chemical and biological properties, the nano-liposomal encapsulation would improve the in vivo circulation and stability. </P><P> Objective: To develop a long-circulating liposomal delivery systems encapsulated APs-CGA-N12 with PEGylated lipids and cholesterol, and investigated through in vivo pharmacokinetics. Methods: The liposomes were prepared and characterized, a rapid and simple liquid chromatographytandem mass spectrometry (LC-MS/MS) assay was developed for the determination of antifungal peptide in vivo, the pharmacokinetic characteristics of APs liposomes were evaluated in rats. Results: Liposomes had a large, unilamellar structure, particle size and Zeta potential ranged from 160 to 185 nm and -0.55 to 1.1 mV, respectively. The results indicated that the plasma concentration of peptides in reference solutions rapidly declined after intravenous administration, whereas the liposomeencapsulated ones showed slower elimination. The AUC(0-∞) was increased by 3.0-fold in liposomes in comparison with standard solution (20 mg·kg-1), the half-life (T1/2) was 1.6- and 1.5-fold higher compared to the reference groups of 20 and 40 mg·kg-1, respectively. Conclusion: Therefore, it could be concluded that liposomal encapsulation effectively improved the bioavailability and pharmacokinetic property of antifungal peptides.


2014 ◽  
Vol 38 (3) ◽  
pp. 353-370 ◽  
Author(s):  
Anna Laura Capriotti ◽  
Chiara Cavaliere ◽  
Patrizia Foglia ◽  
Susy Piovesana ◽  
Salvatore Ventura

2016 ◽  
Vol 51 ◽  
pp. 69-75 ◽  
Author(s):  
Amornrassamee Jinnarak ◽  
Pattarapon Anantavichian ◽  
Apichai Intanin ◽  
Suchada Fungladda ◽  
Nathawut Choengchan ◽  
...  

1995 ◽  
Vol 28 (2) ◽  
pp. 259-266 ◽  
Author(s):  
H. Horie∗ ◽  
G. A. Rechnitz

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