Neonatal Tetanus At The Niger Delta University Teaching Hospital: A 5 Year Retrospective Study

Author(s):  
M. O. Mohammed ◽  
M. Sirajo ◽  
O. O. Okechi ◽  
A. T. Muhammad ◽  
R. I. Tsamiya ◽  
...  

Introduction: Fungal infection is a common manifestation in this part of the country and worldwide. It is essential to define the epidemiology of fungal infection in a particular environment. Aim: This study aims to analyze the diagnosis of fungal infection carried out in patients attending the histopathology department (UDUTH) Sokoto from 2014 to 2018. Method: This study is a retrospective study of all fungal infection biopsies carried out from 2014 – 2019 in Usmanu Danfodiyo University Teaching Hospital, Sokoto, northwestern Nigeria, a referral centre for the neighbouring northern states Kebbi and Zamfara. Ethical clearance was obtained from the ethical committee of UDUTH, data was collected from histological report cards and analyze manually. Some tissue blocks of the case were retrieved to confirm the diagnosis. A total of 66 requests for fungal diagnosis were received from January 2014 to December 2018, which represent about 0.7% of the total biopsies received over the study period. Result: Out of the 66 of request for fungal diagnosis 32(48.5%) were fungal positive. Subcutaneous mycosis was the most frequent fungal infection with a frequency of 18(56.25%). Males were more frequently affected than females with the frequencies of 18(56.25%) and 14 (43.75%) respectively.


2012 ◽  
Vol 6 (12) ◽  
pp. 847-853 ◽  
Author(s):  
Olusola Adetunji Oyedeji ◽  
Francis Fadero ◽  
Victor Joel-Medewase ◽  
Peter Elemile ◽  
Gabriel Ademola Oyedeji

Introduction: Tetanus accounts for high morbidity and case fatality rates in developing countries. This study therefore aimed to identify reasons for the persistence of this disease. Methodology: Paediatric admissions at Ladoke Akintola University Teaching Hospital between 1 January 2006 and 31 December 2008 diagnosed with tetanus were studied. Data was analyzed with SPSS 18 and statistical significance was set at p < 0.05. Results: Of the total 1,681 paediatric admissions, 30 (1.8%) had tetanus. Of the 878 neonatal admissions, 8 (0.9%) had tetanus, while 22 (2.7%) of the total 803 post-neonatal admissions had tetanus. Neonatal tetanus admissions were significantly higher in 2006 compared to 2007 and 2008 (7 [2.3%] versus 1 [0.2%] [χ2= 7.50, P=0.01]). Of the eight mothers whose neonates had tetanus, seven did not receive tetanus toxoids in pregnancy and five (62.5%) were secondary school dropouts. Post-neonatal tetanus cases admitted in the years 2006, 2007, and 2008 were 4, 12, and 6 children respectively. Most of these 22 children did not receive tetanus toxoid immunization in their first year of life. None of the 22 children received booster doses of tetanus toxoids after their first years of life. Conclusion: Mothers at risk of their babies having tetanus, such as secondary school dropouts, must be identified antenatally and vaccinated with tetanus toxiod. Their babies should also receive good care post-delivery. Completion of routine tetanus toxoid schedule in the first year and booster doses in the post-neonatal age should be ensured.


2019 ◽  
Vol 21 (1) ◽  
pp. 29
Author(s):  
Sushma Krishna ◽  
KavithaR Dinesh ◽  
Tintu Abraham ◽  
Dilip Panikar ◽  
Sanjeev Singh ◽  
...  

2017 ◽  
Vol 9 (5) ◽  
pp. 99-105
Author(s):  
A. Aliyu Alhaji ◽  
Abdulkadir Isa ◽  
Amadu Lawal ◽  
Dahiru Tukur

Author(s):  
E. F. Eruvwahwe ◽  
E. U. Eric ◽  
O. G. E. Alaba ◽  
M. B. Deele

Objectives: This study aimed to investigate the expressions of p53 and ki67 genes in the characterization of leiomyomas. Materials: Fifty (50) Paraffin embedded tissue blocks were selected from the department of Histopathology, Niger Delta University Teaching Hospital, Okolobri from January 2011 to August 2019. The histological characterization and morphological evaluation were defined using the routine Hematoxylin and Eosin staining method. Immunostaining was done for p53 and ki67 using the manufacturers antibodies. Results: A direct correlation between age and the expression of the p53 gene was also made in this study. It was observed that in patients within the ages of 50-59 and 60-69, there was markedly no expression of the p53 gene whereas in patients within the ages of 20-29, there was still some level of expression (20%) and ages 30-39 (80%) and finally 40-49 (10%). There was no expression (0.0%) of Ki-67 in uterine leiomyomas across all age groups. Conclusion; This study therefore has suggested that based on the percentage of expression, it can rightly be inferred that the p53 gene is a good indicator in the immune-histochemical characterization of leiomyomas as it has good sensitivity and good prognosis as opposed to Ki67.


2018 ◽  
Vol 6 (4) ◽  
Author(s):  
Tunau KA ◽  
Sulaiman R ◽  
Garba JA ◽  
Aliyu FB ◽  
Panti AA ◽  
...  

Background: Hypertensive disorders in pregnancy are multi-organ, heterogeneous disorder of pregnancy associated with significant maternal and neonatal morbidity and mortality. Pre-eclampsia is a condition which typically occurs after 20 weeks of gestation and is characterized by high blood pressure and significant proteinuria. Objective: The aim of the study was to find out the outcome of pregnancies complicated by pre-eclampsia in the teaching hospital in Sokoto, North-West Nigeria. Methods: A five-year retrospective study on the presentation and outcome of management of pre-eclampsia carried out in Usmanu Danfodiyo University Teaching Hospital (UDUTH) between 1st January 2010 and 31st December 2014.


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