Clinical Evaluation of Immunological Parameters in Patients with Malignant Tumors of Head and Neck

The mainstay of curative therapy for head and neck skin cancers relies upon surgery and/or radiation therapy. However, for some aggressive, non-resectable or recurrent tumors, systemic therapy is necessary. Recent emerging classes of drugs have shown to improve survival for high-risk, recurrent, and unresectable variants of these tumors. The goal of this paper is to review options for systemic therapies for head and neck skin cancers including melanoma, non-melanoma skin cancers and other rare and non-malignant tumors.

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Bowel Perforation Presenting as Head and Neck Subcutaneous Emphysema

The American Surgeon ◽

10.1177/0003134821995085 ◽

2021 ◽

pp. 000313482199508

Author(s):

Dezarae R. Leto ◽

Derek T. Clar ◽

David A. Goodman

Keyword(s):

Head And Neck ◽

Chest Wall ◽

Clinical Evaluation ◽

Subcutaneous Emphysema ◽

Balloon Dilatation ◽

Soft Tissues ◽

Bowel Resection ◽

Bowel Perforation ◽

Endoscopic Balloon Dilatation ◽

Endoscopic Balloon

This patient with Crohn's disease underwent endoscopic balloon dilatation of an ileocolic stricture, and shortly thereafter developed subcutaneous emphysema in the soft tissues of her face, neck, and chest wall. Clinical evaluation and imaging revealed peritonitis from perforated bowel. She underwent laparotomy and bowel resection and recovered well. Subcutaneous emphysema in the head and neck from perforated bowel is a rare but recognized presentation of viscus perforation.

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PD-0434: A Prospective Clinical Evaluation of Mirada DLCExpert Auto-Contouring for Head and Neck OARs.

Radiotherapy and Oncology ◽

10.1016/s0167-8140(21)00456-4 ◽

2020 ◽

Vol 152 ◽

pp. S238

Author(s):

C. South ◽

C. Navarro ◽

D.J. Rickard ◽

J. Lynch ◽

K. Wood ◽

...

Keyword(s):

Head And Neck ◽

Clinical Evaluation

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Unusual Malignant Tumors of the Head and Neck

Radiology ◽

10.1148/86.6.1090 ◽

1966 ◽

Vol 86 (6) ◽

pp. 1090-1095 ◽

Cited By ~ 8

Author(s):

Robert Lindberg

Keyword(s):

Head And Neck ◽

Malignant Tumors

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Selected immunological parameters in clinical evaluation of patients with atopic dermatitis

Advances in Dermatology and Allergology ◽

10.5114/ada.2016.60614 ◽

2016 ◽

Vol 3 ◽

pp. 211-218

Author(s):

Anna Rosińska-Więckowicz ◽

Magdalena Czarnecka-Operacz ◽

Zygmunt Adamski

Keyword(s):

Atopic Dermatitis ◽

Clinical Evaluation ◽

Immunological Parameters

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REVIEW OF THE CURRENT STATE OF THE PROBLEM OF PRIMARY DETECTION OF MALIGNANT TUMORS OF THE CAVITY

The actual problems in dentistry ◽

10.18481/2077-7566-2019-15-2-50-55 ◽

2019 ◽

Vol 15 (2) ◽

pp. 50-55

Author(s):

Наталья Нуриева ◽

Natal'ya Nurieva ◽

Александр Гузь ◽

Aleksandr Guz ◽

Александр Захаров ◽

...

Keyword(s):

Oral Cavity ◽

Head And Neck ◽

Malignant Tumors ◽

Malignant Neoplasm ◽

Diagnostic Procedures ◽

Primary Diagnosis ◽

Malignant Neoplasms ◽

Dental Rehabilitation ◽

Late Treatment ◽

Clinically Significant

Subject: malignant neoplasms of the oral cavity, primary detectability, appeal to specialists, terms of treatment before hospitalization. Objective: based on a five-year analysis of the medical records of patients with a verified diagnosis of malignant neoplasm of the oral cavity, to identify significant criteria for primary diagnosis, doctors of the first contact, including non-cancer profile. Methodology. Malignant neoplasms occupy one of the leading places among all medical and social problems. This is due to a number of reasons, among which are particularly high rates of morbidity and mortality, late treatment of patients and frequent disability. the Purpose of early detection of malignant tumors of the oral cavity is to increase the effectiveness and radicality of treatment, increase the possibility of dental rehabilitation, reduction of disability. To write this article, we conducted a five-year analysis of the primary detection of malignant tumors of the oral cavity in 76 patients hospitalized for treatment in the head and neck Department of the Chelyabinsk district Oncology center. All patients with histologically confirmed diagnosis. Everyone needs specialized anti-tumor treatment. In addition to standard diagnostic procedures, all patients were surveyed on the issues of primary complaints and appeals to medical specialists. Results. On the example of the received questionnaires as well as the standard medical examinations conducted upon admission to the head and neck Department, the trends of the primary referral of patients to primary contact doctors, the terms of treatment before referral to a specialized oncological institution, the stage of the process and the presence of metastasis of the primary focus during treatment, the presence of aggravating factors are analyzed. Conclusions. The results for the five-year period in patients with primary malignant neoplasm of the oral cavity were evaluated, practical recommendations on clinically significant symptoms of malignant tumors of the oral cavity, orientation on the timing of observation were given.

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Research Progress of circRNAs in Head and Neck Cancers

Frontiers in Oncology ◽

10.3389/fonc.2021.616202 ◽

2021 ◽

Vol 11 ◽

Author(s):

Panchun Li ◽

Kunjie Zhu ◽

Yongzhen Mo ◽

Xiangying Deng ◽

Xianjie Jiang ◽

...

Keyword(s):

Head And Neck ◽

Malignant Tumors ◽

Treatment Resistance ◽

Disease Diagnosis ◽

Incidence Rates ◽

Head And Neck Cancers ◽

Research Progress ◽

Circular Rnas ◽

Patients With Cancer ◽

High Conservation

Circular RNAs (circRNAs) are a novel type of non-coding RNAs. Because of their characteristics of a closed loop structure, disease- and tissue-specificity, and high conservation and stability, circRNAs have the potential to be biomarkers for disease diagnosis. Head and neck cancers are one of the most common malignant tumors with high incidence rates globally. Affected patients are often diagnosed at the advanced stage with poor prognosis, owing to the concealment of anatomic sites. The characteristics, functions, and specific mechanisms of circRNAs in head and neck cancers are increasingly being discovered, and they have important clinical significance for the early diagnosis, treatment, and prognosis evaluation of patients with cancer. In this study, the generation, characteristics, and functions of circRNAs, along with their regulatory mechanisms in head and neck cancers have been summarized. We report that circRNAs interact with molecules such as transcription and growth factors to influence specific pathways involved in tumorigenesis. We conclude that circRNAs have an important role to play in the proliferation, invasion, metastasis, energy and substance metabolism, and treatment resistance in cancers.

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