Electron Microscopy of the Kidney in Renal Disease and Hypertension: A Clinicopathological Approach.

1981 ◽  
Vol 1 (2) ◽  
pp. 96-96
Author(s):  
J. F. Mahony
Keyword(s):  
Electron Microscopy ◽  
Renal Disease

RENAL HISTOLOGY DURING TREATMENT WITH OXAZOLIDINE-DIONES (TRIMETHADIONE, ETHADIONE, AND PARAMETHADIONE)

PEDIATRICS ◽  
1962 ◽  
Vol 30 (4) ◽  
pp. 601-607
Author(s):  
A. Bergstrand ◽  
C. G. Bergstrand ◽  
N. Engström ◽  
K. M. Herrlin
Keyword(s):  
Electron Microscopy ◽  
Nephrotic Syndrome ◽  
Renal Disease ◽  
Renal Biopsy ◽  
Clinical Symptoms ◽  
Clinical Signs ◽  
Present Knowledge ◽  
Short Report ◽  
Renal Histology ◽  
Renal Changes

Seven patients with petit mal seizures treated with trimethadione, ethadione, or paramethadione for long periods were subjected to renal biopsy at the age of 14½ 16½ years. None of the patients had clinical signs of renal disease at the time of the biopsy, but three of them had previously shown transient hematuria or proteinuria. The renal histology was studied by conventional methods and by electron microscopy, the latter method only including the glomeruli. The changes found must with the present knowledge be regarded as physiological. A short report is given of a patient with phenylketonuria and epilepsy who developed a nephrotic syndrome during treatment with tridione. No definite pathologic renal changes were demonstrated at the when the clinical symptoms had disappeared.

Electron Microscopy in End Stage Renal Disease: A Case of Fabry's Disease

2010 ◽  
Vol 34 (5) ◽  
pp. 307-313 ◽  
Author(s):  
Adriana M. Doldan-Silvero ◽  
Gretl Nunnemacher ◽  
Michael Germain ◽  
Giovanna M. Crisi
Keyword(s):  
Electron Microscopy ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Fabry’S Disease ◽  
Fabry's Disease ◽  
Stage Renal Disease ◽  
End Stage

Renal Disease in Squirrel Monkeys (Saimiri sciureus)

1981 ◽  
Vol 18 (6_suppl) ◽  
pp. 38-44 ◽  
Author(s):  
H. F. Stills ◽  
B. C. Bullock
Keyword(s):  
Electron Microscopy ◽  
Renal Disease ◽  
Squirrel Monkey ◽  
Membranoproliferative Glomerulonephritis ◽  
Light And Electron Microscopy ◽  
Membranous Glomerulonephritis ◽  
Squirrel Monkeys ◽  
Saimiri Sciureus ◽  
Renal Lithiasis ◽  
Focal Sclerosing Glomerulonephritis

Renal lithiasis, pyelonephritis, and glomerulonephritis were common in our colony of Brazilian phenotype squirrel monkeys (Saimiri sciureus), with glomerulonephritis being a major cause of mortality in adult animals. Squirrel monkey glomerulonephritis was divided into four major classifications, based on light and electron microscopy, similar to those of man: focal sclerosing glomerulonephritis, membranoproliferative glomerulonephritis, membranous glomerulonephritis, and a combination of membranoproliferative and membranous glomerulonephritis.

Scanning Electron Microscopy of the glomerulus in diabetic BB/S wistar rats

1987 ◽  
Vol 45 ◽  
pp. 730-731
Author(s):  
R. C. Kaufmann ◽  
F. K. Khosho ◽  
K. S. Amankwah
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Glucose Tolerance ◽  
Renal Disease ◽  
Wistar Rats ◽  
Renal Damage ◽  
Diabetic Rats ◽  
Wistar Strain ◽  
Glucose Tolerance Tests ◽  
Scanning Electron

Renal damage secondary to diabetes seems to be related to the severity and duration of the diabetes. In streptozotocin and alloxan-induced diabetic rats, renal disease is found only in those rats that have glycosuria and then only after the glycosuria has been present for many months. In these animals, the longer they have glycosuria, the more severe the renal damage. In our colony of BB/S Wistar rats, animals that are going. to become frankly diabetic demonstrate clinical diabetes before they begin spilling glucose in their urine. After glycosuria develops, the condition of the animals worsens; yet, the glucose tolerance tests(GTT) remain essentially unchanged. The purpose of this investigation was to study the animals' kidneys to discover if lesions are present at the onset of glycosuria and how severe the lesions are.Rats of our BB/S Wistar strain were used the day they developed glycosuria. Similarly aged non-diabetic animals were used as controls.

Scanning Electron Microscopy of mouse BALB/C/Cd polycystic renal disease

1987 ◽  
Vol 45 ◽  
pp. 932-933
Author(s):  
E. Keyhani ◽  
W. Penasse
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Fine Structure ◽  
Renal Disease ◽  
Solid Tumor ◽  
Single Layer ◽  
The Other ◽  
Distal Tubules ◽  
Number Of Cells ◽  
Scanning Electron

Mouse BALB/C/Cd exhibited spontaneous transplantable kidney adenocarcinoma which affected both sexes and involved both kidneys. This disease is characterized by plain cysts and cysts with single or multiple polyps to solid tumors at various stages of evolution. The fine structure of solid tumor was previously described.Single or multiple (up to 10) cysts were present throughout the cortex parenchyma. Their sizes ranged from 1 to 8 mm in diameter. The cysts occurred from both proximal and distal tubules and were composed of a single layer of cubic-cylindrical epithelial cells. Most cysts exhibited single or multiple focal areas of epithelial polypoid hyperplasia. Single polyps consisted of accumulations of hyperplasic cells piling up on top of each other (Fig. l). The other form consisted of single or multiple branched polyps with a central vascularized core (Fig. 2). The number of cells forming polyps hyperplasia varied between a dozen to up to several hundreds of cells.

scholarly journals Light Chain Proximal Tubulopathy: Expanding the Pathologic Spectrum with and without Deposition of Crystalline Inclusions

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Shree G. Sharma ◽  
Steven M. Bonsib ◽  
Didier Portilla ◽  
Ashutosh Shukla ◽  
Adam B. Woodruff ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Multiple Myeloma ◽  
Renal Disease ◽  
Physicochemical Properties ◽  
Light Chain ◽  
Proximal Tubules ◽  
Light Chains ◽  
Proximal Tubulopathy ◽  
Light Chain Proximal Tubulopathy ◽  
Crystal Accumulation

Light chain proximal tubulopathy (LCPT) is an uncommon form of renal disease associated with dysproteinemias. It is characterized by intracytoplasmic deposition of crystallized mostly kappa monoclonal light chains in proximal tubules (PTs). Crystals are located within lysosomes by electron microscopy (EM). Rare lambda LCPT cases without crystals by EM were described. Retrospectively, we reviewed clinical, light microscopic (LM), immunofluorescence (IF), and EM findings in 9 cases) (8 males, 1 female; mean age 57 years (38–81)) with multiple myeloma. LM showed abundant cytoplasmic droplets in PT cells in all cases. Droplets were also present in the podocytes, endothelial and parietal cells in one case. IF revealed staining of crystals with kappa in 3 and lambda in 6. EM showed electron dense rectangular, rhomboid, or needle shaped crystals in PT cells in 3 cases (33%), one of which had crystals in podocytes and interstitial cells. Six lambda LCPT cases showed no crystals by EM (67%). This may reflect differences in the physicochemical properties of light chains. The mechanisms of crystal accumulation in these cells and the significance of this finding are unknown.

scholarly journals The value of electron microscopy in the diagnosis of renal disease

2016 ◽  
Vol 85 (1) ◽  
pp. 69-72
Author(s):  
Jakub Żurawski ◽  
Aldona Woźniak ◽  
Wiesława Salwa-Żurawska
Keyword(s):  
Electron Microscopy ◽  
Renal Disease
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