Determination of Antimycin-A in Water by Liquid Chromatographic/Mass Spectrometry: Single-Laboratory Validation
2013 ◽
Vol 96
(2)
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pp. 413-421
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Keyword(s):
Abstract An LC/MS method was developed and validated for the quantitative determination and confirmation of antimycin-A (ANT-A) in water from lakes or streams. Three different water sample volumes (25, 50, and 250 mL) were evaluated. ANT-A was stabilized in the field by immediately extracting it from water into anhydrous acetone using SPE. The stabilized concentrated samples were then transported to a laboratory and analyzed by LC/MS using negative electrospray ionization. The method was determined to have adequate accuracy (78 to 113% recovery), precision (0.77 to 7.5% RSD with samples ≥500 ng/L and 4.8 to 17% RSD with samples ≤100 ng/L), linearity, and robustness over an LOQ range from 8 to 51 600 ng/L.
2019 ◽
Vol 64
(5)
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pp. 271-276
2012 ◽
Vol 57
◽
pp. 19-25
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2010 ◽
Vol 53
(3)
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pp. 698-704
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1974 ◽
Vol 50
(3)
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pp. 337-344
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2001 ◽
Vol 759
(1)
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pp. 99-108
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2006 ◽
Vol 42
(2)
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pp. 149-154
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Keyword(s):
2005 ◽
Vol 824
(1-2)
◽
pp. 36-44
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2004 ◽
Vol 807
(2)
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pp. 287-291
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