scholarly journals Polyphenolic Compounds Targeting p53-Family Tumor Suppressors: Current Progress and Challenges

10.5772/56102 ◽  
2013 ◽  
Author(s):  
Nelly Etienne-Selloum ◽  
Israa Dandache ◽  
Tanveer Sharif ◽  
Cyril Auger ◽  
Valerie B.
Keyword(s):  
Tumor Suppressors ◽  
Polyphenolic Compounds ◽  
P53 Family

Abstract A286: The role of p53 family tumor suppressors in mediating response to the Aurora and angiogenic kinase inhibitor ENMD-2076 in triple-negative breast cancer.

2013 ◽  
Author(s):  
Anastasia A. Ionkina ◽  
John J. Tentler ◽  
Timothy P. Newton ◽  
Kelsey L. Brunkow ◽  
Jared S. Johnson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Triple Negative Breast Cancer ◽  
Tumor Suppressors ◽  
Triple Negative ◽  
Kinase Inhibitor ◽  
P53 Family

scholarly journals PU.1 binding to the p53 family of tumor suppressors impairs their transcriptional activity

Oncogene ◽  
2008 ◽  
Vol 27 (24) ◽  
pp. 3489-3493 ◽  
Author(s):  
M P Tschan ◽  
V A Reddy ◽  
A Ress ◽  
G Arvidsson ◽  
M F Fey ◽  
...  
Keyword(s):  
Tumor Suppressors ◽  
Transcriptional Activity ◽  
P53 Family

scholarly journals The p53 Family: A Role in Lipid and Iron Metabolism

2021 ◽  
Vol 9 ◽  
Author(s):  
Kyra Laubach ◽  
Jin Zhang ◽  
Xinbin Chen
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Iron Metabolism ◽  
Tumor Suppressors ◽  
Tumor Suppression ◽  
Critical Role ◽  
Biological Processes ◽  
P53 Family ◽  
Cycle Arrest

The p53 family of tumor suppressors, which includes p53, p63, and p73, has a critical role in many biological processes, such as cell cycle arrest, apoptosis, and differentiation. In addition to tumor suppression, the p53 family proteins also participate in development, multiciliogenesis, and fertility, indicating these proteins have diverse roles. In this review, we strive to cover the relevant studies that demonstrate the roles of p53, p63, and p73 in lipid and iron metabolism.

Antioxidant polyphenolic compounds from Geranium lasiopus Boiss. et Heldr

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
D Sohretoglu ◽  
S Atasayar Sabuncuoglu ◽  
MK Sakar ◽  
H Ozgunes ◽  
O Sterner
Keyword(s):  
Polyphenolic Compounds

Determination and quantitative analysis of the principal polyphenolic compounds present in stem extracts of native Greek islands grape varieties-assessment of their antioxidant activity in Vitro

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
M Anastasiadi ◽  
H Pratsinis ◽  
D Kletsas ◽  
SA Theotokatos ◽  
SA Haroutounian
Keyword(s):  
Antioxidant Activity ◽  
Quantitative Analysis ◽  
Polyphenolic Compounds ◽  
Grape Varieties

Chemotherapy-induced apoptosis in hepatocellular carcinoma (HCC) involves activation of the p53 family and is mediated by signaling via death receptors and mitochondria

2009 ◽  
Vol 47 (01) ◽  
Author(s):  
SJ Seitz ◽  
AE Schulze Schleithoff ◽  
AF Koch ◽  
K Lorenz ◽  
W Stremmel ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Death Receptors ◽  
P53 Family ◽  
Induced Apoptosis

p53 family-regulated apoptosis genes in hepatocellular carcinoma (HCC)

2009 ◽  
Vol 47 (01) ◽  
Author(s):  
HM Mundt ◽  
AF Koch ◽  
AE Schulze Schleithoff ◽  
SJ Seitz ◽  
K Lorenz ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
P53 Family

Polyphenolic compounds from Clusiaceae plants modulating angiogenesis and vascular endothelium

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
A Lavaud ◽  
R Soletti ◽  
P Richomme ◽  
R Andriantsitohaina ◽  
D Guilet
Keyword(s):  
Vascular Endothelium ◽  
Polyphenolic Compounds

Protein-protein interactions of the p53 family with the Bcl-2 family in hepatocellular carcinoma

2011 ◽  
Vol 49 (08) ◽  
Author(s):  
LC König ◽  
M Meinhard ◽  
C Sandig ◽  
MH Bender ◽  
A Lovas ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Protein Interactions ◽  
Protein Protein Interactions ◽  
P53 Family
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