Recent Advances in ZHENG Differentiation Research in Traditional Chinese Medicine

Author(s):  
Shi-Bing Su
2016 ◽  
Vol 11 (11) ◽  
pp. 1934578X1601101 ◽  
Author(s):  
Di Yang ◽  
Wanwan Jia ◽  
Yi Zhun Zhu

Herba Leonuri, also named Chinese Motherwort, has been extensively investigated as an effective agent on the uterus system. Our group has been studying the natural products of Herba Leonuri for several years, and during this period, many biological activities of the drug were recognized. Leonurine (4-guanidino- N-butyl-syringate) is an alkaloid present in Herba Leonuri. Recently, growing evidence has highlighted the therapeutic potential of leonurine in multiple diseases, especially cardiovascular. In this review, we discuss the biological activities of leonurine, as well as recent advances involving this alkaloid.


2015 ◽  
Vol 66 (3) ◽  
pp. 513-522 ◽  
Author(s):  
Yifei Zhong ◽  
Madhav C. Menon ◽  
Yueyi Deng ◽  
Yiping Chen ◽  
John Cijiang He

2020 ◽  
Vol 18 (12) ◽  
pp. 881-889
Author(s):  
Yu-Jie DAI ◽  
Shi-Yao WAN ◽  
Shuai-Shuai GONG ◽  
Jin-Cheng LIU ◽  
Fang LI ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Ya-Nan Song ◽  
Gui-Biao Zhang ◽  
Yong-Yu Zhang ◽  
Shi-Bing Su

Traditional Chinese medicine (TCM) ZHENG is the basic concept of TCM theory. The effectiveness of TCM treatment depends on the accuracy of ZHENG differentiation. ZHENG differentiation, using the “four diagnostic methods,” has the drawbacks of subjectivity and variability. Following development of omics technologies, which study the functional activities of human body from a system-wide perspective, it has been more and more applied in study of objectivity differentiating TCM ZHENG and understanding its biological mechanisms. This paper reviewed the literatures of clinical TCM ZHENG differentiation researches, underlying omics technologies, and indicated the increased trends of related articles with four kinds of omics technologies, including genomics, transcriptomics, proteomics and metabolomics, and the correlations between ZHENG differentiation and findings in omics studies. Moreover, the paper summarized the typical omics application in common studied diseases and TCM ZHENGs and discussed the main problems and countermeasure of ZHENG differentiation researches. The work here may provide a reference for further research of TCM ZHENG differentiation using omics technologies.


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