scholarly journals Biodegradation of Injectable Calcium Phosphate Bone Cements: A Dental Perspective

Author(s):  
Volkan Arisan

Author(s):  
Denton D. Weiss ◽  
Matthew A. Sachs ◽  
Charles R. Woodard


Author(s):  
Yu Qu ◽  
Hui Zhuang ◽  
Meng Zhang ◽  
Yufeng Wang ◽  
Dong Zhai ◽  
...  

Although calcium phosphate cements (CPC) have been clinically used to repair bone defects caused by bone tumor resection, traditional CPC cannot kill the remaining tumor cells after surgery and prevent...



Author(s):  
Coathup Melanie ◽  
Kent Niall ◽  
Hill Robert ◽  
Ferro De Godoy Roberta ◽  
Quak Wenyu ◽  
...  


Author(s):  
Nuan La Ong Srakaew ◽  
Sirirat Tubsungnoen Rattanachan

Self-setting calcium phosphate cement (CPC) has been used in bone repair and substitution due to their excellent biocompatibility, bioactive as well as simplicity of preparation and use. The inherent brittleness and slow degradation are the major disadvantages for the use of calcium phosphate cements. To improve the degradation for the traditional CPC, the apatite cement formula incorporated with β-tricalcium phosphate (β-TCP) with varying concentration were studied and the effect of the pH value of liquid phase on the properties of this new calcium phosphate cement formula was evaluated. The apatite cements containing β-TCP for 10 and 40 wt.% were mixed into the aqueous solution with different pH values and then aging in absolute humidity at 37°C for 7 days. The setting time and phase analysis of the biphasic calcium phosphate were determined as compared to the apatite cement. For proper medical application, the compressive strength, the phase analysis and the degradation of the CPC samples at pH 7.0 and 7.4 were evaluated after soaking in the simulated body fluid (SBF) at 37°C for 7 days. The results indicated that the properties of the samples such as the setting time, the compressive strength related to the phase analysis of the set cements. The high degradation of the CPC was found in the cement with increasing β-TCP addition due to the phase after setting. Apatite formation with oriented plate-like morphology was also found to be denser on the surface of the biphasic bone cements after soaking in SBF for 7 days. The obtained results indicated that the cement containing β-TCP mixed with the liquid phase at pH 7.4 could be considered as a highly biodegradable and bioactive bone cement, as compared to the traditional CPC.



2020 ◽  
Vol 9 (3) ◽  
pp. 155-163
Author(s):  
Esra Güben ◽  
Şule Arıcı ◽  
Dilara Bayır ◽  
Ergün Bozdağ ◽  
Duygu Ege


PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0182109 ◽  
Author(s):  
Anne Bernhardt ◽  
Martha Schamel ◽  
Uwe Gbureck ◽  
Michael Gelinsky




1995 ◽  
Vol 14 (1) ◽  
pp. 4-5 ◽  
Author(s):  
E. FernÁndez ◽  
M. P. Ginebra ◽  
O. Bermúdez ◽  
M. G. Boltong ◽  
F. C. M. Driessens ◽  
...  


2016 ◽  
Vol 721 ◽  
pp. 182-186
Author(s):  
Zilgma Irbe ◽  
Dagnija Loca ◽  
Agnese Pura ◽  
Liga Berzina-Cimdina

α-Tricalcium phosphate is an important ingredient of calcium phosphate bone cements, which are used for bone defect augmentation and repair. In this study sub-micrometre sized α­tricalcium phosphate particles were synthesized by heat treating amorphous calcium phosphate. Size of synthesized particles depended on duration and temperature of heat treatment. Longer duration and higher temperatures produced larger particles. The reactivity of synthesized particles did not correlate with particle size – the smallest particles did not have the highest reactivity. The most reactive particles were prepared at 700-800 °C. The prepared particles were more reactive than those of conventionally synthesized α-tricalcium phosphate.



Sign in / Sign up

Export Citation Format

Share Document