scholarly journals The Regulation of Germline Stem Cells and Their Neighbouring Somatic Cells in the Fruit Fly (Drosophila melanogaster)

Germ Cell ◽  
2018 ◽  
Author(s):  
Sharon Wui Sing Tan ◽  
Yu Cai ◽  
Gyeong Hun Baeg
Keyword(s):  
Stem Cells ◽  
Drosophila Melanogaster ◽  
Somatic Cells ◽  
Fruit Fly ◽  
Germline Stem Cells

scholarly journals Endocrine regulation of female germline stem cells in the fruit fly Drosophila melanogaster

2019 ◽  
Vol 31 ◽  
pp. 14-19 ◽  
Author(s):  
Yuto Yoshinari ◽  
Yoshitomo Kurogi ◽  
Tomotsune Ameku ◽  
Ryusuke Niwa
Keyword(s):  
Stem Cells ◽  
Drosophila Melanogaster ◽  
Fruit Fly ◽  
Endocrine Regulation ◽  
Germline Stem Cells ◽  
Female Germline

scholarly journals Regulation of Mating-Induced Increase in Female Germline Stem Cells in the Fruit Fly Drosophila melanogaster

2021 ◽  
Vol 12 ◽  
Author(s):  
Ryo Hoshino ◽  
Ryusuke Niwa
Keyword(s):  
Stem Cells ◽  
Drosophila Melanogaster ◽  
Energy Demand ◽  
Seminal Fluid ◽  
Fruit Fly ◽  
Egg Laying ◽  
Germline Stem Cells ◽  
Humoral Factors ◽  
Mating Response ◽  
Sex Peptide

In many insect species, mating stimuli can lead to changes in various behavioral and physiological responses, including feeding, mating refusal, egg-laying behavior, energy demand, and organ remodeling, which are collectively known as the post-mating response. Recently, an increase in germline stem cells (GSCs) has been identified as a new post-mating response in both males and females of the fruit fly, Drosophila melanogaster. We have extensively studied mating-induced increase in female GSCs of D. melanogaster at the molecular, cellular, and systemic levels. After mating, the male seminal fluid peptide [e.g. sex peptide (SP)] is transferred to the female uterus. This is followed by binding to the sex peptide receptor (SPR), which evokes post-mating responses, including increase in number of female GSCs. Downstream of SP-SPR signaling, the following three hormones and neurotransmitters have been found to act on female GSC niche cells to regulate mating-induced increase in female GSCs: (1) neuropeptide F, a peptide hormone produced in enteroendocrine cells; (2) octopamine, a monoaminergic neurotransmitter synthesized in ovary-projecting neurons; and (3) ecdysone, a steroid hormone produced in ovarian follicular cells. These humoral factors are secreted from each organ and are received by ovarian somatic cells and regulate the strength of niche signaling in female GSCs. This review provides an overview of the latest findings on the inter-organ relationship to regulate mating-induced female GSC increase in D. melanogaster as a model. We also discuss the remaining issues that should be addressed in the future.

The male stem cell niche of Drosophila melanogaster: Interactions between the germline stem cells and the hub

2019 ◽  
Vol 383 (1) ◽  
pp. 111489
Author(s):  
Veronica Persico ◽  
Giuliano Callaini ◽  
Maria Giovanna Riparbelli
Keyword(s):  
Stem Cells ◽  
Drosophila Melanogaster ◽  
Stem Cell ◽  
Stem Cell Niche ◽  
Germline Stem Cells ◽  
Cell Niche

The germline stem cells of Drosophila melanogaster partition DNA non-randomly

2009 ◽  
Vol 88 (7) ◽  
pp. 397-408 ◽  
Author(s):  
Phillip Karpowicz ◽  
Milena Pellikka ◽  
Evelyn Chea ◽  
Dorothea Godt ◽  
Ulrich Tepass ◽  
...  
Keyword(s):  
Stem Cells ◽  
Drosophila Melanogaster ◽  
Germline Stem Cells

scholarly journals Ballchen is required for self-renewal of germline stem cells in Drosophila melanogaster

Biology Open ◽  
2014 ◽  
Vol 3 (6) ◽  
pp. 510-521 ◽  
Author(s):  
B. Herzig ◽  
T. A. Yakulov ◽  
K. Klinge ◽  
U. Gunesdogan ◽  
H. Jackle ◽  
...  
Keyword(s):  
Stem Cells ◽  
Drosophila Melanogaster ◽  
Germline Stem Cells ◽  
Self Renewal

scholarly journals Reduction of Cullin-2 in somatic cells disrupts differentiation of germline stem cells in the Drosophila ovary

2015 ◽  
Vol 405 (2) ◽  
pp. 269-279 ◽  
Author(s):  
Champakali Ayyub ◽  
Kushal Kr. Banerjee ◽  
Prakash Joti
Keyword(s):  
Stem Cells ◽  
Somatic Cells ◽  
Germline Stem Cells ◽  
Drosophila Ovary ◽  
Cullin 2

scholarly journals Importin α1 is required for maintaining germline stem cells in Drosophila melanogaster testes

2017 ◽  
Vol 145 ◽  
pp. S163-S164
Author(s):  
James Heaney ◽  
Franca Casagranda ◽  
Gary Hime
Keyword(s):  
Stem Cells ◽  
Drosophila Melanogaster ◽  
Germline Stem Cells

scholarly journals The impact of genetic background and gender on the increase in mitotic index in response to mating of Drosophila melanogaster

2020 ◽  
Author(s):  
Manashree Malpe ◽  
Cordula Schulz
Keyword(s):  
Stem Cells ◽  
Drosophila Melanogaster ◽  
Stem Cell ◽  
Mitotic Activity ◽  
Genetic Background ◽  
Control Specimen ◽  
Germline Stem Cells ◽  
And Gender ◽  
And Control ◽  
The Impact

SUMMARYThe replenishment of specialized cells depends on the activity of stem cells. Recent advances in stem cell research have shown that the germline stem cells (GSCs) in Drosophila melanogaster can increase their mitotic activity in response to mating. Here, we show that this ability to respond to mating is eliminated if the males are mutant for the ABC transporter, White, the genetic background for a plethora of fly lines. Furthermore, we were not able to reproduce previous findings that female flies increase their GSC numbers and mitotic activity upon mating. Our findings underline the importance of careful experimental design and control specimen.

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