scholarly journals Magnetic and Quantum Dot Nanoparticles for Drug Delivery and Diagnostic Systems

2020 ◽  
Author(s):  
Erandi Munasinghe ◽  
Maheshi Aththapaththu ◽  
Lakmal Jayarathne
Keyword(s):  
Drug Delivery ◽  
Quantum Dot ◽  
Diagnostic Systems

Multifunctional quantum dot–polypeptide hybrid nanogel for targeted imaging and drug delivery

Nanoscale ◽  
2014 ◽  
Vol 6 (19) ◽  
pp. 11282-11292 ◽  
Author(s):  
Jie Yang ◽  
Ming-Hao Yao ◽  
Lang Wen ◽  
Ji-Tao Song ◽  
Ming-Zhen Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dot ◽  
Cancer Diagnosis ◽  
Targeted Imaging ◽  
New Class

A new class of multifunctional quantum dot (QD)–polypeptide hybrid nanogel with targeted imaging and drug delivery properties is reported as a nanocarrier for use in cancer diagnosis, imaging, and therapy.

Biopolymer Encapsulation of CdTe Quantum Dot for In Vitro Controlled Drug Delivery Release of 6-Mercaptopurine

2012 ◽  
Vol 584 ◽  
pp. 258-262 ◽  
Author(s):  
Sundarrajan Parani ◽  
Baddireddi Subhadra Lakshmi ◽  
Kanniyan Pandian
Keyword(s):  
Drug Delivery ◽  
Folic Acid ◽  
Quantum Dot ◽  
Drug Carrier ◽  
Controlled Drug Delivery ◽  
Release Profile ◽  
Drug Release Profile ◽  
The Stability ◽  
Cdte Quantum Dot

Alginate biopolymer stabilized CdTe quantum dot (QD) was prepared and it was encapsulated with folic acid conjugated chitosan for controlled drug delivery of anticancer drug 6-mercaptopurine (6-MP). In addition to alginate, chitosan enhances the stability of QD. Also, in addition to chitosan, alginate binds to the drug leading to enhance the loading efficiency of the resulting drug carrier. The drug release profile of the carrier was investigated by in-vitro. The present study has shown that this drug carrier is feasible for drug delivery and will be important beneficiary for cancer therapy.

Quantum Dot-Based Nanotools for Bioimaging, Diagnostics, and Drug Delivery

ChemBioChem ◽  
2016 ◽  
Vol 17 (22) ◽  
pp. 2103-2114 ◽  
Author(s):  
Regina Bilan ◽  
Igor Nabiev ◽  
Alyona Sukhanova
Keyword(s):  
Drug Delivery ◽  
Quantum Dot

scholarly journals Microfluidic Platforms for Evaluation of Nanobiomaterials: A Review

2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
Venkataraman Giridharan ◽  
YeoHeung Yun ◽  
Peter Hajdu ◽  
Laura Conforti ◽  
Boyce Collins ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Traditional Approach ◽  
Cell Communication ◽  
Degradable Polymers ◽  
Diagnostic Systems ◽  
Concentration Gradients ◽  
Microfluidic Platforms ◽  
Cell Tissue ◽  
Wide Range ◽  
Materials Used

Biomaterials, especially those based on nanomaterials, have emerged as critical tools in biomedical applications. The applications encompass a wide range such as implantable devices, tissue regeneration, drug delivery, diagnostic systems, and molecular printing. The type of materials used also covers a wide range: metals (permanent and degradable), polymers (permanent and degradable), carbon nanotubes, and lipid nanoparticles. This paper explores the use of microfluidic platforms as a high-throughput research tool for the evaluation of nanobiomaterials. Typical screening of such materials involves cell/tissue cultures to determine attributes such as cell adhesion, proliferation, differentiation, as well as biocompatibility. In addition to this, other areas such as drug delivery and toxicity can also be evaluated via microfluidics. Traditional approach for screening of such materials is very time-consuming, and a lot of animals should be sacrificed since it involves one material and a single composition or concentration for a single test. The microfluidics approach has the advantage of using multiple types of drugs and their concentration gradients to simultaneously study the effect on the nanobiomaterial and its interaction with cell/tissue. In addition to this, microfluidics provides a unique environment to study the effect of cell-to-extracellular interaction and cell-to-cell communication in the presence of the nanobiomaterials.

scholarly journals Stimuli-Responsive Polymeric Nanosystem for Colon Specific Drug Delivery

2019 ◽  
Vol 10 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Sharon Kunnath Joseph ◽  
Mangalath Sabitha ◽  
Sreeja Chandrasekharan Nair
Keyword(s):  
Drug Delivery ◽  
Chemical Change ◽  
Specific Drug ◽  
Stimuli Responsive ◽  
Diagnostic Systems ◽  
Nanodrug Delivery ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers ◽  
Environment Temperature ◽  
Colon Specific Drug Delivery

An ideal colon specific drug delivery system needs to perform multiple functions like greater bio availability, less toxicity and higher therapeutic efficacy, all of which require high degree of smartness. This article focuses on the overview of the stimuli-responsive polymers and various nanodrug delivery systems which have found applications in colon specific delivery of drugs as this system provide a link between therapeutic need and drug delivery. These polymers exhibit a non-linear response to a small stimulus leading to a macroscopic alteration in their structure/properties. Stimuli responsive polymers display a significant physio chemical change in response to small changes in their environment (temperature, pH, light etc.). Colonic drug delivery has gained increased importance in treating diseases like Crohn’s disease, ulcerative colitis, colon cancer etc. The expansion in the development of polymers based system with greater flexibility, versatility and unexplored potential enables new opportunities for them in uplifting bio medicine. Applying the concepts of smartness in the context of clinically relevant therapeutic and diagnostic systems, it can prelude in a new era of ‘smart’ therapeutics that can improve the health care fields. In particular, due to its high sensitivity to the stimuli, this system has been identified as a sensible platform for releasing drug at suitable site and at appropriate time.

Chitosan/carbon quantum dot/aptamer complex as a potential anticancer drug delivery system towards the release of 5-fluorouracil

2020 ◽  
Vol 165 ◽  
pp. 1422-1430 ◽  
Author(s):  
Hediyeh Sepahi Zavareh ◽  
Mehrab Pourmadadi ◽  
Ali Moradi ◽  
Fatemeh Yazdian ◽  
Meisam Omidi
Keyword(s):  
Drug Delivery ◽  
Quantum Dot ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Anticancer Drug Delivery ◽  
Carbon Quantum Dot
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