scholarly journals Thyroid Function in Pregnancy and Its Influences on Maternal and Fetal Outcomes

Author(s):  
Forough Saki ◽  
Mohammad Hossein Dabbaghmanesh ◽  
Seyede Zahra Ghaemi ◽  
Sedighe Forouhari ◽  
Gholamhossein Ranjbar Omrani ◽  
...  
2011 ◽  
Vol 22 (3) ◽  
pp. 169-187
Author(s):  
NEIL K VANES ◽  
JOHN H LAZARUS ◽  
SHIAO-Y CHAN

Thyroid hormones are important in the development of the fetus and the placenta as well as in maintaining maternal wellbeing. Thyroid disorders are common in the population as a whole, particularly in women, and therefore are common during pregnancy and the puerperium. Biochemical derangement of thyroid function tests are present in approximately 2.5–5% of pregnant women.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A849-A850
Author(s):  
Mohamed Fahmy Amara

Abstract Background: Pregnancy is associated with significant but reversible changes in the thyroid function that might cause maternal and fetal complications. Undetected and untreated thyroid disorders are associated with adverse maternal and fetal outcomes, thus screening is important. There are limited data on the prevalence of newly diagnosed thyroid disease during pregnancy from Egypt. Therefore, this study was designed to evaluate the prevalence of thyroid dysfunction during the three trimesters of pregnancy. Subjects and Methods: This was a cross-sectional study conducted at the antenatal clinic of El-Shatby Maternity Hospital at Alexandria University. The total sample population comprised of 90 pregnant women divided into 30 women for each trimester compared with 30 non- pregnant healthy women regarding thyroid function parameters and thyroid peroxidase antibody (anti - TPO) by using COBAS analyzer measured by the electrochemiluminescence immunoassay “WCLIA” employs monoclonal antibodies specifically directed against human thyroid-stimulating hormone (TSH), free thyroxine (FT4), FT3 and anti TPO. Results: 120 ladies were enrolled for this study aged between 20-45 years excluding subjects with previously diagnosed endocrinal anomalies. There were significant differences between pregnant and non-pregnant females regarding TSH and FT4, but no significant difference regarding FT3 and anti TPO in all trimesters. Conclusion: There is a discrepancy between FT4 & TSH in pregnancy due to the presence of other stimulatory and inhibitory factors in pregnancy, thyroid anomalies increased with the advance in pregnancy, thus screening of TSH and anti TPO is important. Considering the immense impact that maternal thyroid dysfunction has on maternal and fetal outcomes, prompt identification of thyroid dysfunction and its timely treatment is essential.


1990 ◽  
Vol 32 (2) ◽  
pp. 141-152 ◽  
Author(s):  
ROBIN H. MORTIMER ◽  
SHIRLEY A. TYACK ◽  
JOHN P. GALLIGAN ◽  
DONALD A. PERRY-KEENE ◽  
YONG M. TAN

Midwifery ◽  
2021 ◽  
pp. 103128
Author(s):  
Zahra Alipour ◽  
Parisa Samadi ◽  
Narges Eskandari ◽  
Maryam Ghaedrahmati ◽  
Mostafa Vahedian ◽  
...  

2016 ◽  
Vol 9 (3) ◽  
pp. 126-129 ◽  
Author(s):  
Helen Robinson ◽  
Philip Robinson ◽  
Michael D’Emden ◽  
Kassam Mahomed

Background First-trimester care of maternal thyroid dysfunction has previously been shown to be poor. This study evaluates early management of thyroid dysfunction in pregnancy in Australia. Methods Patients reviewed by the Obstetric Medicine team for thyroid dysfunction from 1 January 2012 to 30 June 2013 were included. Data were collected on gestation at referral from the patient’s general practitioner to the antenatal clinic, information provided in the referral letter, thyroid function tests and thyroid medications. Results Eighty-five women were included in the study. At the time of general practitioner referral to antenatal services, 19% of women with preexisting thyroid disease had no thyroid function tested. Forty-three percent had an abnormal thyroid-stimulating hormone defined as being outside the laboratory-specific pregnancy reference range if available, or outside the level of 0.1–2.5 mIu/L in the first trimester, 0.2–3.0 mIu/L in the second trimester and 0.3–3.0 mIu/L in the third trimester. Only 21% of women increased their thyroxine dose prior to their first antenatal clinic review. Conclusion This study highlights that a significant proportion of women with known thyroid disease either have untested thyroid function in the first trimester or a thyroid-stimulating hormone outside of levels recommended by guidelines.


2016 ◽  
Vol 2016 (7) ◽  
pp. 138-140 ◽  
Author(s):  
Rebecca F. D'Cruz ◽  
Sher M. Ng ◽  
Pooja Dassan
Keyword(s):  

2016 ◽  
Vol 9 (4) ◽  
pp. 169-170 ◽  
Author(s):  
A Wijemanne ◽  
I Watt-Coote ◽  
S Austin

Glanzmann thrombasthenia is a rare autosomal recessive haemorrhagic disorder. The risks of miscarriage, antepartum and postpartum haemorrhage, and neonatal complications are all increased in individuals presenting with the disease in pregnancy. Some individuals may develop antibodies to platelet glycoproteins; the presence of these antibodies is a rare cause of neonatal alloimmune thrombocytopenia and potential intracranial haemorrhage. Multidisciplinary care is paramount for ensuring optimal fetal and maternal outcomes in such cases. We report a case of neonatal alloimmune thrombocytopenia secondary to maternal Glanzmann thrombasthenia in pregnancy.


Author(s):  
Dhivya Sethuraman ◽  
Nirmala Ramachandran ◽  
SAP Noorjahan ◽  
Vijay Kanna

2021 ◽  
Vol 27 (1) ◽  
pp. 27-33
Author(s):  
Aysel Kalaycı Yiğin ◽  
Mustafa Tarık Alay ◽  
Mehmet Seven

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