scholarly journals Short Term Outcome of Neonates Born with Abnormal Umbilical Cord Arterial Blood Gas

2015 ◽  
Vol 25 (1) ◽  
Author(s):  
Mousa Ahmadpour Kacho ◽  
Yadollah Zahedpasha ◽  
Mohsen Haghshenas ◽  
Zahra Akbarian Rad ◽  
Bahram Sadat Nasseri ◽  
...  
2015 ◽  
Vol 30 (6) ◽  
pp. 593-598 ◽  
Author(s):  
Rahul Choudhary ◽  
Ashish Goel ◽  
Sonal Pruthi ◽  
Sarathi Kalra ◽  
Sunil Agarwal ◽  
...  

AbstractIntroductionWith an increasing number of sicker patients, limited hospital beds, and an emphasis on day care, the profile of patients hospitalized to medicine wards has undergone a radical re-definition. The increasing share of patients hospitalized through the emergency department for acute care to medicine wards has left little space for hospitalization through the outpatient department (OPD). There are some global data available on the profile of patients presenting to the emergency rooms (ERs) and their subsequent outcome. Data from developing countries, especially India, in this regard are lacking.MethodsThis cross-sectional study included all patients hospitalized to the medicine ward through the medical emergency services, provided by the Department of Medicine, each Wednesday and every sixth Sunday for the entire year (a total of 62 days), from November 2010 through October 2011, and followed their outcome up to seven days after hospitalization.ResultsOf the 3,618 cases presenting to medicine emergency on these days, 1,547 (42.3%) were advised admission. Nine hundred sixty-seven reported to the medicine wards. One hundred eleven (7.73%) expired within 24 hours; others absconded, were lost in transit, did not consent to participation, or were discharged. During the next seven days, 452 (46.7%) recovered sufficiently and were discharged to go home. Two hundred thirty (23.8%) left the hospital without informing the medical staff. Fourteen (1.4%) patients were transferred to other departments. One hundred thirty-seven (8.8%) patients died during the next six days of hospitalization. After Multivariate Logistic Regression analysis, abnormal Glasgow Coma Scale (GCS) score, high systolic blood pressure (BP), age, increased total leucocyte count, increased globulin, low bicarbonate in arterial blood, low Mini Mental Status Examination (MMSE) score, and a raised urea >40 mg/dL were found to be associated significantly with mortality.ConclusionOf the 1,547 patients who needed urgent hospitalization, 248 (16%) died within the first week, one-half of them within the first 24 hours. An advanced age, abnormal GCS score, low MMSE score, increased systolic BP, leukocytosis, acidosis, and uremia were found to be associated with a fatal outcome. Therefore, nearly one-half of the patients who would have a fatal short-term outcome were likely to do so within the first 24 hours, making the first day of presentation “the golden day” period.ChoudharyR, GoelA, PruthiS, KalraS, AgarwalS, KalraOP. Profile of patients hospitalized through the emergency room to the medicine ward and their short-term outcome at a tertiary care hospital in Delhi. Prehosp Disaster Med. 2015;30(6):593–598.


2013 ◽  
Vol 89 (12) ◽  
pp. 1037-1040 ◽  
Author(s):  
Carlo Dani ◽  
Cecilia Bresci ◽  
Elettra Berti ◽  
Silvia Lori ◽  
Maria Rosaria Di Tommaso ◽  
...  

2021 ◽  
pp. 002367722199315
Author(s):  
Maria AAP Santos ◽  
Tiago MC Lucera ◽  
Mônica Horr ◽  
Isabella N Santana ◽  
Ewaldo Mattos-Junior

The aim of this study was to compare the cardiorespiratory, arterial blood gas and antinociceptive effects of dexmedetomidine (D), dexmedetomidine–lidocaine (DL) or lidocaine (L) administered epidurally on conscious rabbits. Eight six-month-old male New Zealand rabbits were randomly distributed into three treatments: D (2.5 μg/kg); DL (2.5 μg/kg; 2 mg/kg); and L (2 mg/kg). The drugs were injected epidurally via a catheter. Cardiorespiratory, arterial blood gas and antinociceptive variables were recorded before administration, 5 and 10 min after drug administration, then every 10 min until the animals presented a positive response to nociceptive stimulation of perineal dermatomes. Two animals had permanent paralysis after DL treatment due to hemorrhage and congestion with neuron necrosis in spinal cord segments. There was a reduction in mean arterial pressure in treatment L at 5 and 10 min, compared with the baseline, and in treatment DL at 10–30 min. Increases in pH were observed in treatment D at 5 and 10 min, and in DL at all the times evaluated, compared with the baseline. No alterations were observed in other blood gas or electrolyte variables. Antinociceptive effects were evaluated in the perineal, sacral and lumbar regions, and were restricted to the perineal region following D and L treatment. The antinociceptive effects following DL were greater than D and L alone in all of the regions. L and D promotes short-term antinociceptive effects for up to 15 min and, when used in combination with D, increased the duration and extent of sensory block by up to 45 min.


2017 ◽  
Vol 4 (4) ◽  
pp. 1325
Author(s):  
Pradeep Meena ◽  
Mahendra Meena ◽  
Maheshwar Gunawat

Background: Birth/Perinatal asphyxia is one of the common cause of neonatal morbidity and mortality. Morbidity and mortality in asphyxia depends on duration and severity of asphyxia. The present study was carried out to find out the correlation of APGAR score and cord blood pH with severity of birth asphyxia and short-term outcome.Methods: An observational hospital based prospective study was conducted at inborn NICU, of Medical College Hospital of Southern Rajasthan from March 2015 to September 2015. We enrolled total 50 inborn asphyxiated newborns as cases. The cord blood was collected immediately at delivery for measurement of cord blood arterial blood gas analysis including pH. All the enrolled cases were admitted in the NICU for treatment and observation for complication and immediate neurological outcome. All the admitted newborns were followed till discharge/death for final outcome. The correlation of APGAR score, cord blood pH and outcome was analysed statistically.Results: The mean APGAR score at 1 min, 5 min and mean cord blood pH in babies with HIE-I were 4.40±0.89, 6.80±0.45 and 7.21±0.11; HIE-II 3.70±0.67, 6.0±1.25 and 7.20±0.06; HIE-III 2.69±0.60, 3.56±0.8 and 7.03±0.11, respectively. Correlation coefficients of APGAR 1 min, 5 min and cord blood pH to predict the severity of birth asphyxia were -0.633, -0.666 and 0.624.Conclusions: Cord blood pH at birth in combination with APGAR score can be used to predict the severity of birth asphyxia and short-term outcome. APGAR score and cord blood pH are inversely related with the duration and severity asphyxia. 


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