scholarly journals Differences in the Brain Cortical Thickness and Area of Different Lobes Between Fetuses with Intrauterine Growth Restriction and Controls Based on 3-Tesla Magnetic Resonance Imaging (MRI)

2021 ◽  
Vol 18 (2) ◽  
Author(s):  
Behnaz Moradi ◽  
Mahboobeh Shirazi ◽  
Zohreh Alibeigi Nezhad ◽  
Nazanin Seyed Saadat ◽  
Hassan Hashemi ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cortical Thickness ◽  
Intrauterine Growth Restriction ◽  
Brain Regions ◽  
Growth Restriction ◽  
Control Group ◽  
Resonance Imaging ◽  
Intrauterine Growth ◽  
Magnetic Resonance Imaging Mri ◽  
The Brain

Background: Intrauterine growth restriction (IUGR) is a major factor in long-term perinatal morbidity and is associated with abnormal fetal brain development; however, its pattern of brain involvement remains unknown. Objectives: This study aimed to investigate the effect of IUGR on the brain parenchyma. Methods: Forty-two women with IUGR pregnancy and 28 women with normally grown fetuses at 28 - 38 weeks of pregnancy underwent 3-tesla magnetic resonance imaging (MRI). Cortical thickness was assessed in four regions and corrected by the biparietal diameter/2. Also, the whole brain surface area (WBA) was measured, and the areas of six brain regions were calculated and corrected by WBA. Results: In the IUGR group, the cortical thickness in the insula and temporal lobe was significantly thinner than the control group (0.034 vs. 0.043 and 0.036 vs. 0.047, respectively; P < 0.05); these fetuses also showed significantly reduced WBA (P = 0.028). The corrected brain areas were not significantly different between the groups, except for the corrected areas of the cerebellum and the hippocampus, which increased in the IUGR group as compared to the control group (0.147 vs. 0.130 and 0.017 vs. 0.0125, respectively; P < 0.05). Conclusions: In the IUGR fetuses, significantly thinner insular cortex and temporal lobe cortex and smaller WBA were found compared to the control group. Among different brain regions, the cerebellum and the hippocampus were less affected by growth restriction in the antenatal period.

scholarly journals Advanced techniques in magnetic resonance imaging of the brain in children with ADHD

2011 ◽  
Vol 69 (2a) ◽  
pp. 242-252 ◽  
Author(s):  
Giuseppe Pastura ◽  
Paulo Mattos ◽  
Emerson Leandro Gasparetto ◽  
Alexandra Prufer de Queiroz Campos Araújo
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Cortical Thickness ◽  
Diffusion Tensor ◽  
Brain Regions ◽  
Resonance Imaging ◽  
Brain Volumetry ◽  
Aged Child ◽  
Magnetic Resonance Imaging Mri ◽  
The Brain

Attention deficit hyperactivity disorder (ADHD) affects about 5% of school-aged child. Previous published works using different techniques of magnetic resonance imaging (MRI) have demonstrated that there may be some differences between the brain of people with and without this condition. This review aims at providing neurologists, pediatricians and psychiatrists an update on the differences between the brain of children with and without ADHD using advanced techniques of magnetic resonance imaging such as diffusion tensor imaging, brain volumetry and cortical thickness, spectroscopy and functional MRI. Data was obtained by a comprehensive, non-systematic review of medical literature. The regions with a greater number of abnormalities are splenium of the corpus callosum, cingulated girus, caudate nucleus, cerebellum, striatum, frontal and temporal cortices. The brain regions where abnormalities are observed in studies of diffusion tensor, volumetry, spectroscopy and cortical thickness are the same involved in neurobiological theories of ADHD coming from studies with functional magnetic resonance imaging.

scholarly journals Magnetic resonance imaging of skull and brain parameters in fetuses with intrauterine growth restriction

2021 ◽  
Vol 54 (3) ◽  
pp. 141-147
Author(s):  
Ronaldo Eustáquio de Oliveira Júnior ◽  
Sara Reis Teixeira ◽  
Eduardo Félix Martins Santana ◽  
Jorge Elias Junior ◽  
Fabricio da Silva Costa ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Intrauterine Growth Restriction ◽  
Normal Growth ◽  
Growth Restriction ◽  
Resonance Imaging ◽  
Intrauterine Growth ◽  
Magnetic Resonance Imaging Mri ◽  
Length And Area ◽  
Brain Measurements

Abstract Objective: To compare fetuses with intrauterine growth restriction (IUGR) and those with normal growth, in terms of skull and brain measurements obtained by magnetic resonance imaging (MRI). Materials and Methods: This was a prospective cohort study including 26 single fetuses (13 with IUGR and 13 with normal growth), evaluated from 26 to 38 weeks of gestation. Using MRI, we measured skull and brain biparietal diameters (BPDs); skull and brain occipitofrontal diameters (OFDs); corpus callosum length and area; transverse cerebellar diameter; extracerebral cerebrospinal fluid (eCSF); and right and left interopercular distances (IODs). Results: The following were significantly smaller in IUGR fetuses than in control fetuses: skull BPD (76.9 vs. 78.2 mm; p = 0.0029); brain BPD (67.8 vs. 71.6 mm; p = 0.0064); skull OFD (93.6 vs. 95 mm; p = 0.0010); eCSF (5.5 vs. 8.2 mm; p = 0.0003); right IOD (9.8 vs. 13.9 mm; p = 0.0023); and left IOD (11.8 vs. 16.3 mm; p = 0.0183). The skull BPD/eCSF, brain BPD/eCSF, skull OFD/eCSF, and brain OFD/eCSF ratios were also lower in IUGR fetuses. Conclusion: IUGR fetuses had smaller OFD and BPD, both skull and brain, and less eCSF when compared to normal growth fetuses.

Impact of intrauterine growth restriction and glucocorticoids on brain development: Insights using advanced magnetic resonance imaging

2006 ◽  
Vol 254-255 ◽  
pp. 163-171 ◽  
Author(s):  
Stéphane V. Sizonenko ◽  
Cristina Borradori-Tolsa ◽  
Delphine M. Vauthay ◽  
Gregory Lodygensky ◽  
François Lazeyras ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Brain Development ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Resonance Imaging ◽  
Intrauterine Growth

scholarly journals Difference of brain cortical thickness and area of different lobes between fetuses with intrauterine growth restriction and control group assessed by 3 Tesla MRI

2020 ◽  
Author(s):  
Behnaz Moradi ◽  
Mahboobeh Shirazi ◽  
Zohreh Alibeigi nezhad ◽  
Nazanin Seyed Saadat ◽  
Hassan Hashemi ◽  
...  
Keyword(s):  
Cortical Thickness ◽  
Fetal Brain ◽  
Brain Regions ◽  
Growth Restriction ◽  
Control Group ◽  
P Value ◽  
Intrauterine Growth ◽  
Brain Surface ◽  
Fetal Brain Development ◽  
And Control

AbstractBackgroundIntrauterine growth restricted (IUGR) is a major factor of perinatal and long-term morbidity and is associated with abnormal fetal brain development but its pattern of brain involvement is still unknown.Materials and Methods42 women with IUGR pregnancy and 28 women with normally-grown fetuses between 28-38 weeks underwent 3Tesla MRI. Cortical thickness was assessed in 4 regions and was corrected by biparietal diameter/2. Also, whole brain surface area (WBA) and areas of 6 brain regions were included and corrected by WBA.ResultsIUGR fetuses had significantly thinner cortical thickness in the insula and temporal lobes compared to the control group (0.034 vs 0.043 and 0.036 vs 0.047 respectively, P value of < 0.05). They had significantly reduced WBA (P value: 0.028). The corrected brain areas were not significantly different between groups except for the corrected areas of cerebellum and hippocampus which were increased in IUGR fetuses compared to the control group (0.147vs 0.130,0.017vs 0.0125 respectively, P value of < 0.05).ConclusionIUGR fetuses had significantly thinner insular and temporal lobe cortex and smaller WBA compared to the control group. Among different brain regions, cerebellum and hippocampus were less affected by growth restriction in utero period.

Foetal volumetry using Magnetic Resonance Imaging in intrauterine growth restriction

2012 ◽  
Vol 88 ◽  
pp. S35-S40 ◽  
Author(s):  
Mellisa S. Damodaram ◽  
Lisa Story ◽  
Elisanda Eixarch ◽  
Prachi Patkee ◽  
Abhilasha Patel ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Resonance Imaging ◽  
Intrauterine Growth

scholarly journals Magnetic Resonance Imaging in Pregnancy with Intrauterine Growth Restriction: A Pilot Study

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Serafina Perrone ◽  
Antonino Santacroce ◽  
Giuseppe de Bernardo ◽  
Maria Gabriella Alagna ◽  
Salvatore Francesco Carbone ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Amniotic Fluid ◽  
Fetal Growth ◽  
Gestational Age ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Resonance Imaging ◽  
Intrauterine Growth ◽  
Respiratory Outcome

Objective. Intrauterine growth restriction (IUGR) is a major cause of late stillbirth, though not all compromised babies remain small or are considered growth restricted as pregnancy progresses. Fetal Magnetic Resonance Imaging (f-MRI) represents a second-line tool to study pregnancies with IUGR fetuses. The aim of our study was to evaluate the usefulness of f-MRI on predicting fetal growth and the offspring’s perinatal respiratory outcome. Design. All f-MRI performed between 2014 and 2016 in Siena were analysed. Pregnancies with IUGR (Study group (SG)) were recruited together with a control population (Control group (CG)), coupled for gestational age (GA) at the time of f-MRI (mean GA 31 wks). Neonatal information was collected. The f-MRI protocol consisted of T2w images. Six regions of interest (ROI) were placed as follows: 2 on the lung, 2 on the liver, and 2 on the amniotic fluid. The signal intensities (SI) of each ROI were measured. The SI lung to liver ratio (SI lung/liver) and SI lung to amniotic fluid ratio (SI lung/amniotic fluid) were obtained for each fetus. Each ratio was compared between SG and CG. Therefore, SG was divided into two subgroups: adequate and small for gestational age (AGA and SGA) newborns. All measurements were related to offspring’s perinatal respiratory outcome. Results. SI lung/liver was linearly related with GA at the time of f-MRI and with EFW. SI lung/amniotic fluid was significantly higher in SG than in CG (p=0,014). In contrast, among SG, lower values of SI lung/amniotic fluid were found in the SGA compared to AGA (p=0,036). The days of oxygen supply were higher in the SGA subgroup than in the AGA subgroup (p=0,028). Conclusions. SI lung/liver increases with fetal lung maturation and appears to be useful to estimate intrauterine fetal growth. SI lung/amniotic fluid seems to be a reliable predictive index to distinguish the IUGR fetuses that can recover their growth from those that were born SGA. f-MRI represents a promising frontier to predict IUGR fetus outcome, thus contributing to ameliorate the perinatal management.

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