scholarly journals MicroRNAs as Regulatory Elements of Mammalian Spermatogenesis

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Fatemeh Malekvandfard ◽  
Leila Zare ◽  
Seyedeh Sahar Mortazavi Farsani ◽  
Mahsa Motavaf

: In recent decades, infertility is becoming a public health issue. Male spermatogenesis failure has been considered a major contributory factor to infertility. Mammalian spermatogenesis is a well-defined process, requiring highly regulation processes in both transcriptional and the posttranscriptional levels. Discovery of microRNAs (miRNAs or miR) as essential class of gene expression regulators has provided new insights into a multitude of biological processes including spermatogenesis. In current review study, we first provide a short overview of spermatogenesis process, and then focus on recent studies that have elucidated the essential role of miRNAs in different steps of sperm production.

2017 ◽  
Vol 9 (1) ◽  
pp. 27-32
Author(s):  
Jannatul Fardows ◽  
S. M. Shamsuzzaman

Bangladesh J Med Microbiol 2015; 9 (1): 27-32


2019 ◽  
Vol 19 (20) ◽  
pp. 1707-1716 ◽  
Author(s):  
Miao Li ◽  
Meng Pan ◽  
Chengzhong You ◽  
Jun Dou

MiRNAs play an important role in cancers. As a potent tumor suppressor, miRNA-7(miR-7) has been demonstrated to inhibit the diverse fundamental biological processes in multiple cancer types including initiation, growth and metastasis by targeting a number of molecules and signaling pathways. This current review summarizes and discusses the relationship between miR-7 and cancers and the therapeutic potential of miR-7 in cancers. It may provide new integrative understanding for future study on the role of miR-7 in cancers.


Author(s):  
Maria Ines Zanoli Sato

This chapter provides a review of infectious disease to date and the challenges they may present in the future. The main pandemics that have driven the history of humanity are described, from the first to be recorded in 3180 BC to more recent ones such as AIDIS, SARS and others associated with emerging pathogens. The essential role of emerging scientific specialisms (particularly microbiology, public health and sanitary engineering) to our understanding of the causes of these diseases (and how they may be better monitored, controlled and prevented) is presented. Globalization and climate change, determining factors for the ecology of infectious diseases and their emergence and re-emergence, are discussed and point to the urgent need for research to deal with these threats that continue to have a significant impact on human development and wellbeing.


Author(s):  
Ivis García ◽  
Keuntae Kim

Homelessness is a public health issue that many organizations are addressing through a Housing First Model. One such organization is The Road Home (TRH), which provides services to homeless individuals and families in Salt Lake County. TRH is perhaps best known for their emergency shelters, but the organization also administers the Rapid Rehousing Program (RRHP), designed to help families experiencing homelessness transition back into stable housing. Those experiencing homelessness tend to have high rates of chronic mental/physical disabilities as well as issues related to substance abuse. Having a home is the first step toward achieving some kind of stability in their lives. The RRHP allows families to find housing in the private rental market and will cover the initial costs and several months of rent for clients. While the program has been praised by policymakers and social service providers for helping homeless families find rental housing, there is no empirical research about participant perspectives regarding their residential (in)security. The research question of this article is: what is the role of the RRHP in supporting the security of families experiencing homelessness? Researchers collected qualitative data through focus groups and interviews with 31 participants, 23 families experiencing homelessness, two landlords, six case managers, and service providers. Lastly, we identify recommendations for program improvements based on information gathered from research participants. It is our hope that the information presented in this article can and will be used in a way that improves public health by increasing the residential security of families experiencing homelessness.


1989 ◽  
Vol 8 (1) ◽  
pp. 53-63 ◽  
Author(s):  
Alan J. Bush ◽  
Victoria Davies

AIDS in the United Slates may be the most urgent public health issue facing public policy makers today. Since there is currently no chemical cure or vaccine for the AIDS virus, the only weapons available for prevention are public information and education. This study assesses the role of advertising in disseminating information during the AIDS crisis by interviewing the state AIDS coordinators in each of the 48 contiguous United States. The results of the study summarize what the states are currently doing with their AIDS advertising campaigns. Additionally, state AIDS coordinators’ perceptions are presented on advertising's role during the AIDS crisis, and what can be done to improve current AIDS advertising campaigns. Finally, implications for public policy makers are discussed.


2020 ◽  
Vol 23 (5) ◽  
pp. 361-367 ◽  
Author(s):  
Michael Y. Uohara ◽  
James N. Weinstein ◽  
David C. Rhew

2007 ◽  
Vol 31 (5) ◽  
pp. 438-443 ◽  
Author(s):  
Karen Willis ◽  
Jeanne Daly ◽  
Michelle Kealy ◽  
Rhonda Small ◽  
Glenda Koutroulis ◽  
...  

2019 ◽  
Vol 47 (S2) ◽  
pp. 39-42 ◽  
Author(s):  
Brittney Crock Bauerly ◽  
Russell F. McCord ◽  
Rachel Hulkower ◽  
Dawn Pepin

Broadband internet access is a super-determinant of health that plays an important role in healthcare and public health outcomes. Laws and policies shape implementation and use of broadband for healthcare and public health. Connecting broadband and telehealth laws with their health impacts, through legal epidemiological research, enables states to make evidence-based decisions to improve health outcomes for underserved populations.


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