scholarly journals The Effect of High-Intensity Interval Training with and Without Caloric Restriction on Spatial Learning and Long-Term Memory of Obese Rats

2019 ◽  
Vol 6 (4) ◽  
Author(s):  
Sedigheh Karampour ◽  
Ali Asghar Ravasi ◽  
Siroos Choobineh
2021 ◽  
Vol 19 (2) ◽  
Author(s):  
Hossein Taheri Chadorneshin ◽  
Shila Nayebifar ◽  
Seyed-Hosein Abtahi-Eivary ◽  
Hossein Nakhaei

Objectives: This study aimed to investigate the effects of six-week continuous training (CT) and high-intensity interval training (HIIT) protocols on brain superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX) activities and their associations with short-, mid-, and long-term memory in albino Wistar rats. Methods: In this study, 18 male albino Wistar rats (5 months old) were randomly assigned to three equal (n = 6) groups of sedentary control (SC), CT, and HIIT. Both CT and HIIT regimens were performed for 6 consecutive days per week for 6 weeks. Results: Both HIIT and CT regimens increased short-, mid-, and long-term memory, and the alterations were greater following HIIT than CT. In addition, both HIIT and CT regimens significantly increased SOD activity, with a higher elevation following HIIT than CT. Moreover, brain SOD activity positively correlated with short-, mid-, and long-term memory. However, neither CT nor HIIT had a significant effect on brain GPX and CAT activities. Conclusions: The HIIT regimen is highly potential, as opposed to the CT regimen, to improve memory function through a greater increase in the SOD activity of the brain.


2019 ◽  
Author(s):  
Wesley Pyke ◽  
Fadi Ifram ◽  
Laura Coventry ◽  
Yee Sung ◽  
Isabelle Champion ◽  
...  

Objectives Many studies have looked at the effects of physical exercise on long-term memory. However, to date, no study has compared the effect of different intensities and protocols of physical exercise and different rest conditions on long-term memory. Methods In three studies (N=59) we measured the extent that physical exercise (in its varying intensities) and wakeful rest (active-rest; in which participants were cognitively engaged while seated and passive-rest; no cognitive engagement while seated) could influence long-term memory. Across all three studies, nearly identical procedures were employed, using the same old/new recognition memory test in order to establish the most effective protocol for cognitive enhancement. In Study 1, the effects of continuous moderate intensity exercise, uninterrupted wakeful rest (passive) and rest with an engagement task (active) were explored. In Study 2, continuous moderate intensity exercise was compared to high-intensity interval training (HIIT) and passive rest. Study 3 observed the effects of low-, moderate- and high-intensity continuous exercise. Results Across the three studies moderate intensity exercise had the greatest positive impact on memory performance. Passive rest was more effective than active rest, however, less than high-intensity interval-training (HIIT). Conclusion Our findings suggest that it is not necessary to physically overexert oneself in order to achieve observable improvements to long-term memory. By also investigating uninterrupted wakeful rest, it reaffirmed the importance of the consolidation period for the formation of long-term memories.


2017 ◽  
Vol 6 (2) ◽  
pp. 103-110 ◽  
Author(s):  
Koichiro Azuma ◽  
Yusuke Osawa ◽  
Shogo Tabata ◽  
Fuminori Katsukawa ◽  
Hiroyuki Ishida ◽  
...  

2020 ◽  
Vol 5 (12) ◽  
pp. 1382
Author(s):  
Jenna L. Taylor ◽  
David J. Holland ◽  
Shelley E. Keating ◽  
Michael D. Leveritt ◽  
Sjaan R. Gomersall ◽  
...  

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Josefin Ansund ◽  
Sara Mijwel ◽  
Kate A. Bolam ◽  
Renske Altena ◽  
Yvonne Wengström ◽  
...  

Abstract Background Adjuvant systemic breast cancer treatment improves disease specific outcomes, but also presents with cardiac toxicity. In this post-hoc exploratory analysis of the OptiTrain trial, the effects of exercise on cardiotoxicity were monitored by assessing fitness and biomarkers over the intervention and into survivorship. Methods; Women starting chemotherapy were randomized to 16-weeks of resistance and high-intensity interval training (RT-HIIT), moderate-intensity aerobic and high-intensity interval training (AT–HIIT), or usual care (UC). Outcome measures included plasma troponin-T (cTnT), Nt-pro-BNP and peak oxygen uptake (VO2peak), assessed at baseline, post-intervention, and at 1- and 2-years. Results For this per-protocol analysis, 88 women met criteria for inclusion. Plasma cTnT increased in all groups post-intervention. At the 1-year follow-up, Nt-pro-BNP was lower in the exercise groups compared to UC. At 2-years there was a drop in VO2peak for patients with high cTnT and Nt-pro-BNP. Fewer patients in the RT-HIIT group fulfilled biomarker risk criteria compared to UC (OR 0.200; 95% CI = 0.055–0.734). Conclusions In this cohort, high-intensity exercise was associated with lower levels of NT-proBNP 1-year post-baseline, but not with cTnT directly after treatment completion. This may, together with the preserved VO2peak in patients with low levels of biomarkers, indicate a long-term cardioprotective effect of exercise. Trial registration Clinicaltrials.govNCT02522260, Registered 13th of august 2015 – Retrospectively Registered Graphical abstract


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