scholarly journals A Case of Gastric Cancer, Presenting with Extensive Lymphangitis Carcinomatosa in the Gastric Wall, Though Primary Lesion Remained in the Submucosal Layer

2003 ◽  
Vol 36 (9) ◽  
pp. 1269-1274
Author(s):  
Susumu Hijioka ◽  
Toshihiko Hirata ◽  
Hiroshi Yokomizo ◽  
Hiroshi Fujita ◽  
Hiroshi Kako ◽  
...  
Author(s):  
Carlos Eduardo Jacob ◽  
Claudio Bresciani ◽  
Joaquim José Gama-Rodrigues ◽  
Osmar Kenji Yagi ◽  
Donato Mucerino ◽  
...  

BACKGROUND: Gastric cancer (GC) is a predominately male disease. Usually for every female that suffers from this condition there are two males and occurred an increase in the number of females in last decades. Brazil is poor in data about this issue. AIM: To verify if in Brazil it happened: a) a change in the gender ratio and on the average age of the patients; b) an increase in the number of patients with 70 years of age or more suffering from this disease; c) changes in the gender ratio and in the average age in the several gastric locations during the period of study. METHODS: The medical history of patients diagnosed with primary gastric adenocarcinoma, between 1971 and 1998 were obtained at Hospital das Clínicas of the University of São Paulo, São Paulo, SP, Brazil. Exclusion criteria were: patients suffering from a non epithelial gastric malignancy; adenocarcinoma from the intestinal metaplasia in the distal esophagus invading the proximal stomach and patients submitted to a gastric resection, due to a benign or malignant tumor during the last five years prior to the surgical procedure analyzed in this study. The patients were divided into 10 years age groups and also divided in three groups, according to their ages and time intervals. Interrelationships between gender and age, and with tumor´s location on gastric wall were analyzed. RESULTS: From 1971 to 1998, 1578 patients with GC were hospitalized. Among them, 1021 were treated with gastric resection, corresponding to 64.7% of all patients. There was an increase in the proportion of patients older than 70 years, and decrease between 41 and 70 years. There was no statistical significant difference among the average ages and the different locations. There were significant differences for the locations favoring proximal third and stump, both more prevalent in males. CONCLUSIONS: a) Occurred modifications in the ratio between genders: greater number of women and an increase in the number of male patients in the age group between 41 and 70 years; b) it was proved the greater number of occurrences in patients over 70 years of age; c) there was a greater increase in the male predominance in the tumors located in the stomach´s proximal third.


2007 ◽  
Vol 40 (10) ◽  
pp. 1673-1678 ◽  
Author(s):  
Shunichi Ishigami ◽  
Morito Sakikubo ◽  
Ryou Kamimura ◽  
Katsuaki Ura ◽  
Hideaki Ooe ◽  
...  

2019 ◽  
Vol 12 (12) ◽  
pp. e231796 ◽  
Author(s):  
Margarida Rodrigues Fonseca ◽  
Mariana Constante ◽  
Anne Moura ◽  
Ivone Melo Valadão

Emphysematous gastritis is a rare disease characterised by air in the wall of the stomach due to gas-forming microorganisms. This is a highly lethal entity for which only prompt diagnosis and treatment can avoid mortality. Different factors have been described that disrupt the integrity of the mucosa such as corrosive ingestion, alcohol abuse, recent abdominal surgery or cancer. We report a case of emphysematous gastritis in a 92-year-old woman who presented to the emergency department with abdominal pain, nausea and vomiting. Inflammatory markers were elevated and abdominal X-rays showed intramural gastric air, confirmed by CT scan. The patient received intravenous fluids, nutritional support and broad-spectrum antibiotic with resolution of gastric wall emphysema. However, the diagnosis of poorly cohesive gastric adenocarcinoma was made and the patient was referred to palliative care. This case highlights the importance of prompt recognition of this lethal entity that represents a rare and aggressive presentation of gastric cancer.


2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Bogdan Małkowski ◽  
Tomasz Staniuk ◽  
Ewa Śrutek ◽  
Tomasz Gorycki ◽  
Wojciech Zegarski ◽  
...  

The aim of the study was to evaluate the usefulness of 18F-FLT PET/CT in the detection and differentiation of gastric cancers (GC). 104 consecutive patients (57 cases of adenocarcinoma tubulare (G2 and G3), 17 cases of mucinous adenocarcinoma, 6 cases of undifferentiated carcinoma, 14 cases of adenocarcinoma partim mucocellulare, and 10 cases of end stage gastric cancer) with newly diagnosed advanced gastric cancer were examined with FLT PET/CT. For quantitative and comparative analyses, the maximal standardized uptake value (SUVmax) was calculated for both the tumors and noninvaded gastric wall.Results.There were found, in the group of adenocarcinoma tubulare,SUVmax1.5–23.1 (7.46±4.57), in mucinous adenocarcinoma,SUVmax2.3–10.3 (5.5±2.4), in undifferentiated carcinoma,SUVmax3.1–13.6 (7.28±3.25), in adenocarcinoma partim mucocellulare,SUVmax2–25.3 (7.7±6.99), and, in normal gastric wall,SUVmax1.01–2.55 (1.84±0.35). For the level of 2.6 cut-off value between the normal wall and neoplasm FLT uptake from ROC analysis, all but five gastric cancers showed higher accumulation of FLT than noninfiltrated mucosa.Conclusion.Gastric cancer presents higher accumulation of 18F-FLT than normal, distended gastric mucosa. Significantly higher accumulation was shown in cancers better differentiated and with higher cellular density.


2018 ◽  
Vol 1 (4) ◽  
pp. 10-21
Author(s):  
Rizvan Yagubovich Abdullaiev ◽  
Irina Victorovna Kryzhanovskaya ◽  
Youri Alekseevich Vinnik ◽  
Philip Narteh Gorleku

Introduction: Ultrasound study of locally advanced gastric cancer that has spread to adjoining tissue and lymph nodes. This tumor can be associated with T2 to T4 stages of cancer. A “Locally advanced gastric cancer” is a tumor, which may be categorized as ‘resectable’ cancer when compared with M1 advanced cancer. Objective: The aim of this study was to evaluate the Capabilities of transabdominal ultrasonography in assessment of structures and functional disorders of the locally advanced gastric cancer of diverse localization Materials and Methods: A total of61 patients with locally advanced gastric cancer were analyzed of which 36 (59,0%) were males (mean age 62.7 years) and 25 (41,0%) were females (mean age 59.3 years). All patients were managed surgically and underwent preoperative X-ray, virtual gastroscopy techniques, multidetector computed tomography and transabdominal ultrasonography (USG). Histopathology results found, in 58 (95,1%) cases adenocarcinoma, in 3 (4,9%) – ring-cell carcinoma (cricoidal) gastric cancer was established. Stage T2 was diagnosed in 16 (26.2%) cases, T3 - in 41 (67.2%) cases, T4 - in 4 (6.6%) cases. The stomach tumor in 29 (47.5%) cases was localized mainly in the antrum, 27 (44.3%) – in the body, 5 (8.2%) in the cardia and fundus (Table 1). In 24 (39,3%) cases, pyloric stenos was diagnosed - of which in 6 (9,8%) it was compensated, in 18 (29,5%) - sub compensated. All patients underwent preoperative X-ray, virtual gastroscopy techniques, multidetector computed tomography and transabdominal ultrasonography (USG). Normal ultrasound features were observed in 35 patients without gastric pathology. Ultrasonography was carried out with the convex and micro convex transducers in the frequency range of 2-5 MHz and 4-7 MHz respectively in B and color Doppler modes. Results: The polypoid type of gastric cancer was detected in 3 (4,9±2,8%) cases, the ulcerative type – in 18 (29,5±5,8%), the infiltrative ulcerative type – in 27 (44,3±6,4%) and the diffuse infiltrative type – in 13 (21,3%±5,2%) cases respectively. In 24 (39,3%) cases, pyloric stenos was diagnosed - of which in 6 (9,8%) it was compensated, in 18 (29,5%) – sub compensated. The layers of the gastric wall were not differentiated in all patients with sub compensated pyloric stenos. The gastric wall thickness of the affected area was 10,2±2,9mm in the case compensated pyloric stenosis, the length was 27,1±6,2mm, the diameter of the pylorus was 8,3±0,8mm. Among patients with sub compensated pyloric stenos, the thickness of the gastric wall was 19,8±4,1mm, the length was 43,6±4,5mm, the pyloric diameter was 4,3±1,1mm. Among the 61 patients studied, pathological vascularization was detected in 42 (68.8%) cases. It was observed that, all 4 (6.5%) patients with gastric cancer were stage T4 and 38 (62.3%) were stage T3. Vascularization was weak in 13 cases, in 24 cases - moderate, and in 5 cases - enhanced. Metastases to the regional lymph nodes were diagnosed in 52 cases. Ultrasonographically, they were detected only in 37 (71.2%) cases. Conclusions: In the diagnosis of locally advanced gastric cancer, ultrasonography demonstrates good capabilities for determining the extent and depth of the affected area. Color doppler mode allows the study of vascularisation of a locally thickened area, as well as nearby enlarged lymph nodes, which is very important to ascertain the degree of malignancy of the hyperplastic process. ltrasonography can independently determine the degree of pyloric stenosis in patients with distal gastric cancer.


2017 ◽  
Vol 63 (2) ◽  
pp. 294-297
Author(s):  
Marina Grinkevich ◽  
Viktor Klimenko ◽  
Aleksandr Shcherbakov ◽  
Oleg Tkachenko

The aim of the study was to evaluate the effectiveness of endoscopic resection of mucosa by dissection in submucosa in treatment for early gastric cancer. The study included 78 patients with early differentiated gastric cancer of stages T1aN0M0 (65) and T1bN0M0 (13) who underwent endoscopic resection of mucosa by dissection in the submucosal layer at the N.N. Petrov Research Institute of Oncology. According to results of our study endoscopic resection of mucosa by dissection in the submucosal layer in early gastric cancer is highly effective (98.7%) and is a relatively safe method of organ-preserving radical treatment with a high quality of life in the long-term period, which allows it to be recommended as an option of choice for this pathology.


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