scholarly journals Measurements in First-Trimester Abortion Products: A Pathologic Study

2019 ◽  
Vol 144 (2) ◽  
pp. 207-214
Author(s):  
Rosete Nogueira ◽  
Sara Sousa ◽  
Ana Cristina Braga ◽  
Ana Azevedo ◽  
Nuno Pereira ◽  
...  
Keyword(s):  
Clinical Information ◽  
First Trimester ◽  
Retrospective Case ◽  
Trimester Abortion ◽  
Pathology Laboratory ◽  
Crown Rump Length ◽  
Pathologic Study ◽  
Gestational Sac ◽  
Retrospective Case Study ◽  
Umbilical Cords

Context.— Related to the advances in prenatal diagnosis and the emergence of medically challenging situations, there has been an increased interest in conducting a pathologic study of first-trimester abortion products. Objective.— To evaluate measurements across a large group of first-trimester spontaneous abortion specimens. Potential goals include a validation of prenatal embryo and gestational-sac measurements as a function of gestational age (GA). Design.— A retrospective case study of first-trimester spontaneous abortions between June 2015 and April 2017 in Centro de Genética Clínica Embryo-Fetal Pathology Laboratory, Porto, Portugal. Considering the inclusion criteria, 585 complete gestational sacs, 182 embryos, and 116 umbilical cords were selected. We recorded the weight of the gestational sacs and embryos and measurements of gestational sacs, umbilical cords, and embryo crown-rump length. Models were computed using regression techniques. Results.— Gestational-sac diameter percentiles 5, 25, 50, 75 and 95 were calculated according to GA, and at each 1-week interval the diameter increased an average of 3 mm. Umbilical cord length percentiles 5, 25, 50, 75 and 95 were calculated according to GA, and at each 1-week interval, the length increased an average of 1.35 mm. Embryo crown-rump length estimated mean ± SD values were GA 6 weeks, 5.3 ± 2.3 mm; GA 7 weeks, 9.4 ± 4.8 mm; GA 8 weeks, 13.7 ± 8.2 mm; GA 9 weeks, 20.8 ± 9.1 mm; GA 10 weeks, 22.6 ± 13.4 mm; GA 11 weeks, 29.4 ± 12.9 mm; and GA 12 weeks, 52 mm. Conclusions.— Pathologic measurements obtained should be compared to expected measurements and correlated with ultrasound findings, clinical information, and microscopic findings. Deviations from expected values could lead to an understanding of early pregnancy loss.

First-trimester fetal growth discordance and development of preeclampsia in dichorionic twin pregnancies

2015 ◽  
Vol 43 (6) ◽  
Author(s):  
Tanya Maric ◽  
Natasha Singh ◽  
Keith Duncan ◽  
Guy J. Thorpe-Beeston ◽  
Makrina D. Savvidou
Keyword(s):  
Fetal Growth ◽  
Case Control Study ◽  
Subsequent Development ◽  
First Trimester ◽  
Case Control ◽  
Retrospective Case ◽  
Crown Rump Length ◽  
Significant Difference ◽  
Twin Pregnancies ◽  
Control Study

AbstractTo investigate the relation between first-trimester fetal growth discrepancy, as assessed by crown-rump length (CRL) at 11+0 to 13+6 weeks of gestation, and subsequent development of preeclampsia (PE) in dichorionic diamniotic (DCDA) twin pregnancies. The association between inter-twin CRL and birth weight (BW) discrepancy was also investigated.This was a retrospective, case-control study of DCDA twin pregnancies. Inter-twin CRL discrepancy was calculated as 100×(larger CRL–smaller CRL)/larger CRL. BW discordance was calculated as 100×(larger BW–smaller BW)/larger BW.The study included 299 DCDA pregnancies that remained normotensive and 35 that subsequently developed PE. There was no significant difference in the inter-twin CRL discrepancy between pregnancies complicated by PE and those that were not [3.2%, interquartile range (IQR): 0.5–4.5% vs. 3.3%, IQR: 1.4–5.5%; P=0.17]. There was a positive correlation between inter-twin CRL and BW discrepancy but only in pregnancies that remained normotensive (P<0.001). In women that subsequently developed PE, there was no association between inter-twin CRL and BW discordance (P=0.54).In unselected DCDA twins, first-trimester CRL discrepancy is not different between pregnancies that subsequently develop PE and those that remain normotensive. Furthermore, in pregnancies that are complicated by PE, the association between inter-twin CRL and BW discrepancy appears to be lost.

STUDY OF PRENATAL DEVELOPMENTAL EVENTS IN FIRST TRIMESTER OF PREGNANCY IN KHYBER PAKHTUN KHUWA: AN ULTRASONIC STUDY

JKCD ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 15-18
Author(s):  
Munila Shabnum Khattak
Keyword(s):  
Gestational Age ◽  
Growth Parameters ◽  
Abdominal Ultrasound ◽  
First Trimester ◽  
Yolk Sac ◽  
Cross Sectional ◽  
Crown Rump Length ◽  
Developmental Anatomy ◽  
First Trimester Of Pregnancy ◽  
Gestational Sac

Objective: To study the prenatal developmental anatomy in first trimester of pregnancy in Khyber Pakhtun Khuwa. Materials and methods: The cross sectional study was conducted on 600 pregnant females visiting the antenatal clinic of Khyber Teaching Hospital Peshawar and Khyber clinic (Jamrud). The duration of study was 6 months. A pregnant women greater than 16 years of age, willing for ultrasound was selected, poor visualization due to technical factors like obesity, surgical scar were excluded. All the patients were enlisted under informed consent. Detailed obstetrical history was taken. The embryos were visualized with the help of abdominal ultrasound. Data were recorded followed by statistical analysis and presented as percentages. Results: In the present study, 591 cases (98.5%) were single, 8 (1.33%) cases were twin and one case is (0.16%) of triplets. The distributions of normal and abnormal cases were studied in first trimester. The shape of gestational sac was regular in 370(61.66%) and irregular in 230(38.33%) Yolk sacs were identified in 430(71.6%) cases, while in 170(28.33%) of cases yolk sac could not be identified. It could not be identified in 50 (8.33%) of cases due to early pregnancy and in 120 (20%) of cases due to abnormal pregnancy. The Fetal pole was detected in 150(25%) cases and could not be identified in 450 (75%) of cases. The relationship of gestational age, gestational sac and crown rump length in normal pregnancy was observed. Conclusions: There is linear increase in measurements of fetal growth parameters as the gestational age increases. For the assessment of gestational age in the first trimester, ultrasound is an accurate and useful modality. Key words: Trimester, Gestational sac, Yolk sac and Crown rump length.

Technology and Hospital Information System: A Case of Implementation of Electronic Clinical Records in Hospital Maternity Irene Neto in Lubango, Angola

2019 ◽  
Vol 10 (11) ◽  
pp. 1131-1135
Author(s):  
Tomas Hambili Paulo Sanjuluca ◽  
◽  
Ricardo Correia ◽  
Anabela Antunes de Almeida ◽  
Ana Gloria Diaz Martinez ◽  
...  
Keyword(s):  
Maternity Hospital ◽  
Management Support ◽  
Retrospective Case ◽  
System A ◽  
Clinical Records ◽  
Retrospective Case Study ◽  
The Impact ◽  
And Child Health

Introduction: In order to have a good assessment of the quality of maternal and child health care, it is essential that there is up-to-date and reliable information. Objective: To evaluate the impact of the implementation of a computerized database of clinical processes in the admission, archive and medical statistics section, of Maternity hospital Irene Neto/Lubango-Angola. Methodology: A descriptive study with a quantitative and qualitative approach to carry out a retrospective case study deliveries and newborns, records from 2014 to 2017. Final considerations: The implementation of this project may contribute to the improvement of clinical management support management of the hospital as well as facilitating access to information for research and scientific production.

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