scholarly journals Predictive Value of the Framingham Risk Score in Identifying High Cardiovascular Risk

2015 ◽  
Vol 1 (1) ◽  
Author(s):  
Priscila Valente Fernandes ◽  
Marcelo Machado de Castro ◽  
Alexandre Fuchs ◽  
Marcos Calzada da Rocha Machado ◽  
Fernanda Diniz de Oliveira ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Risk Score ◽  
Predictive Value ◽  
Framingham Risk Score ◽  
High Cardiovascular Risk ◽  
Framingham Risk

scholarly journals Clinical significance of increased arterial stiffness associated with atrial fibrillation, according to Framingham risk score

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Goh Eun Chung ◽  
Hyo Eun Park ◽  
Heesun Lee ◽  
Su-Yeon Choi
Keyword(s):  
Atrial Fibrillation ◽  
Cardiovascular Risk ◽  
High Risk ◽  
Arterial Stiffness ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Risk Groups ◽  
The Elderly ◽  
High Cardiovascular Risk ◽  
Framingham Risk

AbstractAtrial fibrillation (AF) is the most common arrhythmia in the elderly. Arterial stiffness may predict the risk of AF, but this relationship has not been fully evaluated. We assessed the association between arterial stiffness and prevalent AF. All subjects who had electrocardiography performed and a cardio-ankle vascular index (CAVI) calculated during a screening examination between 2010 and 2019 were enrolled. To evaluate the association between increased arterial stiffness and AF, we divided the population according to their Framingham risk score (FRS) into low-, intermediate-, and high-risk groups. A total of 8048 subjects were evaluated. The multivariate analysis revealed that increased arterial stiffness was significantly associated with AF prevalence, even after adjusting cardiovascular risk factors [odds ratio (OR) 1.685, 95% confidence interval (CI) 1.908–2.588, p = 0.017]. When we subcategorized the subjects according to their FRS, increased arterial stiffness was significantly associated with AF in the intermediate- and high-risk groups (OR 3.062, 95% CI 1.39-6.740 and OR3.877, 95% CI 1.142-13.167, respectively, BMI adjusted. High arterial stiffness shows a significant association with AF in those with intermediate or high cardiovascular risk, and can be used for further risk stratification of patients.

scholarly journals Assessment of cardiovascular risk tools as predictors of cardiovascular disease events in systemic lupus erythematosus

2021 ◽  
Vol 8 (1) ◽  
pp. e000448
Author(s):  
Jagan Sivakumaran ◽  
Paula Harvey ◽  
Ahmed Omar ◽  
Oshrat Tayer-Shifman ◽  
Murray B Urowitz ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Cardiovascular Risk ◽  
High Risk ◽  
Negative Predictive Value ◽  
Risk Score ◽  
Predictive Value ◽  
Framingham Risk Score ◽  
Cvd Risk ◽  
Framingham Risk ◽  
Number Of Patients

BackgroundSLE is an independent risk factor for cardiovascular disease (CVD). This study aimed to determine which among QRISK2, QRISK3, Framingham Risk Score (FRS), modified Framingham Risk Score (mFRS) and SLE Cardiovascular Risk Equation (SLECRE) best predicts CVD.MethodsThis is a single-centre analysis on 1887 patients with SLE followed prospectively according to a standard protocol. Tools’ scores were evaluated against CVD development at/within 10 years for patients with CVD and without CVD. For patients with CVD, the index date for risk score calculation was chosen as close to 10 years prior to CVD event. For patients without CVD, risk scores were calculated as close to 10 years prior to the most recent clinic appointment. Proportions of low-risk (<10%), intermediate-risk (10%–20%) and high-risk (>20%) patients for developing CVD according to each tool were determined, allowing sensitivity, specificity, positive/negative predictive value and concordance (c) statistics analysis.ResultsAmong 1887 patients, 232 CVD events occurred. QRISK2 and FRS, and QRISK3 and mFRS, performed similarly. SLECRE classified the highest number of patients as intermediate and high risk. Sensitivities and specificities were 19% and 93% for QRISK2, 22% and 93% for FRS, 46% and 83% for mFRS, 47% and 78% for QRISK3, and 61% and 64% for SLECRE. Tools were similar in negative predictive value, ranging from 89% (QRISK2) to 92% (SLECRE). FRS and mFRS had the greatest c-statistics (0.73), while QRISK3 and SLECRE had the lowest (0. 67).ConclusionmFRS was superior to FRS and was not outperformed by the QRISK tools. SLECRE had the highest sensitivity but the lowest specificity. mFRS is an SLE-adjusted practical tool with a simple, intuitive scoring system reasonably appropriate for ambulatory settings, with more research needed to develop more accurate CVD risk prediction tools in this population.

scholarly journals Assessment of cardiovascular risk of patients with arterial hypertension of a public health unit

2012 ◽  
Vol 10 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Evandro José Cesarino ◽  
André Luiz Gomes Vituzzo ◽  
Julliane Messias Cordeiro Sampaio ◽  
Danilo Avelar Sampaio Ferreira ◽  
Heloísa Andrião Ferreira Pires ◽  
...  
Keyword(s):  
Primary Care ◽  
Cardiovascular Risk ◽  
Arterial Hypertension ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Low Risk ◽  
High Cardiovascular Risk ◽  
Cross Sectional ◽  
Primary Care Unit ◽  
Framingham Risk

OBJECTIVE: To assess the cardiovascular risk, using the Framingham risk score, in a sample of hypertensive individuals coming from a public primary care unit. METHODS: The caseload comprised hypertensive individuals according to criteria established by the JNC VII, 2003, of 2003, among 1601 patients followed up in 1999, at the Cardiology and Arterial Hypertension Outpatients Clinic of the Teaching Primary Care Unit, at the Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo. The patients were selected by draw, aged over 20 years, both genders, excluding pregnant women. It was a descriptive, cross-sectional, observational study. The Framingham risk score was used to stratify cardiovascular risk of developing coronary artery disease (death or non-fatal acute myocardial infarction). RESULTS: Age range of 27-79 years (<img src="/img/revistas/eins/v10n1/carx.jpg" align="absmiddle"> = 63.2 ± 9.58). Out of 382 individuals studied, 270 (70.7%) were female and 139 (36.4%) were characterized as high cardiovascular risk for presenting diabetes mellitus, atherosclerosis documented by event or procedure. Out of 243 stratified patients, 127 (52.3%) had HDL-C < 50 mg/dL; 210 (86.4%) had systolic blood pressure > 120 mmHg; 46 (18.9%) were smokers; 33 (13.6%) had a high cardiovascular risk. Those added to 139 enrolled directly as high cardiovascular risk, totaled up 172 (45%); 77 (20.2%) of medium cardiovascular risk and 133 (34.8%) of low risk. The highest percentage of high cardiovascular risk individuals was aged over 70 years; those of medium risk were aged over 60 years; and the low risk patients were aged 50 to 69 years. CONCLUSION: The significant number of high and medium cardiovascular risk individuals indicates the need to closely follow them up.

scholarly journals A Retrospective Exploratory Analysis on Cardiovascular Risk and Cognitive Dysfunction in Multiple Sclerosis

2021 ◽  
Vol 11 (4) ◽  
pp. 502
Author(s):  
Antonio Reia ◽  
Martina Petruzzo ◽  
Fabrizia Falco ◽  
Teresa Costabile ◽  
Matteo Conenna ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Cognitive Function ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Verbal Learning ◽  
Macrovascular Disease ◽  
Cardiovascular Comorbidities ◽  
Cholesterol Levels ◽  
Framingham Risk ◽  
Input Variables

Background. Cardiovascular comorbidities have been associated with cognitive decline in the general population. Objectives. To evaluate the associations between cardiovascular risk and neuropsychological performances in MS. Methods. This is a retrospective study, including 69 MS patients. For all patients, we calculated the Framingham risk score, which provides the 10-year probability of developing macrovascular disease, using age, sex, diabetes, smoking, systolic blood pressure, and cholesterol levels as input variables. Cognitive function was examined with the Brief International Cognitive Assessment for MS (BICAMS), including the Symbol Digit Modalities Test (SDMT), the California Verbal Learning Test-II (CVLT-II), and the Brief Visuospatial Memory Test-Revised (BVMT-R). Results. Each point increase of the Framingham risk score corresponded to 0.21 lower CVLT-II score. Looking at Framingham risk score components, male sex and higher total cholesterol levels corresponded to lower CVLT scores (Coeff = −8.54; 95%CI = −15.51, −1.57; and Coeff = −0.11; 95%CI = −0.20, −0.02, respectively). No associations were found between cardiovascular risk and SDMT or BVMT-R. Conclusions. In our exploratory analyses, cardiovascular risk was associated with verbal learning dysfunction in MS. Lifestyle and pharmacological interventions on cardiovascular risk factors should be considered carefully in the management of MS, given the possible effects on cognitive function.

Cardiovascular risk prediction in the general population with use of suPAR, CRP, and Framingham Risk Score

2013 ◽  
Vol 167 (6) ◽  
pp. 2904-2911 ◽  
Author(s):  
Stig Lyngbæk ◽  
Jacob L. Marott ◽  
Thomas Sehestedt ◽  
Tine W. Hansen ◽  
Michael H. Olsen ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
General Population ◽  
Risk Prediction ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Framingham Risk ◽  
Cardiovascular Risk Prediction

scholarly journals Baseline Framingham risk score does not predict future ECG-derived QRS duration over an average of 3.3 years

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Elijah Stone ◽  
Yuling Zhou ◽  
Herbert Jelinek ◽  
Craig S. Mclachlan
Keyword(s):  
Cardiovascular Risk ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Cross Sectional ◽  
Online Risk ◽  
Weak Association ◽  
Framingham Risk ◽  
Qrs Duration ◽  
Risk Parameters

Abstract Background Prolonged electrocardiogram (ECG) QRS duration has been associated with increased cardiovascular risk. It is unclear whether the main predictor of cardiovascular risk, the Framingham risk score also predicts short-term changes in ECG QRS duration. Our aim is to determine whether baseline Framingham risk score is associated with baseline or changes in QRS duration. Methods A retrospective cross-sectional analysis was performed using observational data obtained from two hundred two participants. Framingham risk score was calculated using an online risk calculator. QRS duration was obtained using a 10 s trace from a Welch Allyn PC-based 12-lead ECG system. Results Average follow-up duration was 3.3 ± 1.1 years. Mean QRS change was 1.8 ± 11.4 ms. Specifically, among two hundred two participants, there are 104 subjects with a greater QRS duration at follow-up, while 98 subjects had the same or a shorter follow-up QRS duration. Baseline Framingham risk score did not significantly predict an increase in QRSd with an odds ratio of 1.04 (P = 0.230). Regression analysis of QRS duration at baseline and Framingham risk at baseline had a weak association (R2 = 0.020; P = 0.043). The Framingham risk score at follow-up was likewise has a weak association with follow-up QRS duration (R2 = 0.045; P = 0.002). Conclusions Our results do not demonstrate a statistically significant association between Framingham risk parameters and future QRS duration changes over longitudinal time. QRS duration had variable changes between baseline and follow-up. This might suggest that a longer period of follow-up is required to document more stable increases in QRS duration associated with ventricular pathology. A larger population study is needed to confirm our observations.

scholarly journals Long-term predictive value of the Framingham Risk Score for Stroke in HIV-positive vs HIV-negative men

Neurology ◽  
2013 ◽  
Vol 81 (24) ◽  
pp. 2094-2102 ◽  
Author(s):  
F. J. Mateen ◽  
W. S. Post ◽  
N. Sacktor ◽  
A. G. Abraham ◽  
J. T. Becker ◽  
...  
Keyword(s):  
Risk Score ◽  
Predictive Value ◽  
Framingham Risk Score ◽  
Hiv Positive ◽  
Framingham Risk ◽  
Hiv Negative
Sign in / Sign up

Export Citation Format

Share Document