Effects of dual-task interventions on gait performance of patients with Parkinson’s Disease: A systematic review

Objective: The aim of the present study was to systematically evaluate and quantify the effectiveness of dual-task training on gait parameters, motor symptoms and balance in individuals diagnosed with Parkinson’s disease. Data resources: A systematic review of published literature was conducted until May 2020, using PubMed, EMBASE, Cochrane Library, Web of Science, EBSCO and CNKI databases. Methods: We included randomized controlled trials (RCTs) and non-RCTs to evaluate the effects of dual-task training compared with those of non-intervention or other forms of training. The measurements included gait parameters, motor symptoms and balance parameters. Methodological quality was assessed using the PEDro scale. Outcomes were pooled by calculating between-group mean differences using fixed- or random-effects models based on study heterogeneity. Results: A total of 11 RCTs comprising 322 subjects were included in the present meta-analysis. Results showed that dual-task training significantly improved gait speed (standardized mean difference [SMD], −0.23; 95% confidence interval [CI], −0.38 to −0.08; P = 0.002), cadence (SMD, −0.25; 95% CI, −0.48 to −0.02; P = 0.03), motor symptoms (SMD, 0.56; 95% CI, 0.18 to 0.94; P = 0.004) and balance (SMD, −0.44; 95% CI, −0.84 to −0.05; P = 0.03). However, no significant changes were detected in step length or stride length. Conclusion: Dual-task training was effective in improving gait performance, motor symptoms and balance in patients with Parkinson’s disease relative to other forms of training or non-intervention.

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Gait and Cognition in Parkinson’s Disease: Cognitive Impairment Is Inadequately Reflected by Gait Performance during Dual Task

Frontiers in Neurology ◽

10.3389/fneur.2017.00550 ◽

2017 ◽

Vol 8 ◽

Cited By ~ 8

Author(s):

Heiko Gaßner ◽

Franz Marxreiter ◽

Simon Steib ◽

Zacharias Kohl ◽

Johannes C. M. Schlachetzki ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Cognitive Impairment ◽

Dual Task ◽

Gait Performance

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The efficacy of cognitive-cycling dual-task training in patients with early-stage Parkinson’s disease: A pilot study

Neurorehabilitation ◽

10.3233/nre-203090 ◽

2020 ◽

Vol 47 (4) ◽

pp. 415-426

Author(s):

Hsiu-Chen Chang ◽

Chiung-Chu Chen ◽

Yi-Hsin Weng ◽

Wei-Da Chiou ◽

Ya-Ju Chang ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Cognitive Performance ◽

Dual Task ◽

Rating Scale ◽

Early Stage ◽

Freezing Of Gait ◽

Timed Up And Go ◽

Gait Performance ◽

The Mean

BACKGROUND: Recent studies have suggested that cognitive-motor dual-task (DT) training might improve gait performance, locomotion automaticity, balance, and cognition in patients with Parkinson’s disease (PD). OBJECTIVE: We aimed to investigate the efficacy of cognitive-cycling DT training in patients with early-stage PD. METHODS: Participants were scheduled to perform cognitive tasks simultaneously with the cycling training twice per week for eight weeks for a total of 16 sessions during their on-states. Clinical assessments were conducted using the unified Parkinson’s disease rating scale (UPDRS), modified Hoehn and Yahr stage, Timed Up and Go (TUG) test, gait and cognitive performances under dual-task paradigm, the new freezing of gait questionnaire, Schwab and England Activities of Daily Living scale, 39-item Parkinson’s disease questionnaire, and cognitive performance. RESULTS: Thirteen eligible patients were enrolled in the study. The mean age was 60.64±5.32 years, and the mean disease duration was 7.02±3.23 years. Twelve PD patients completed 16 serial cognitive-cycling sessions for two months. After 16 sessions of training (T2), the UPDRS III scores improved significantly in both the off- and on-states, and TUG were significantly less than those at pretraining (T0). During both the single-task and the DT situations, gait performance and spatial memory cognitive performance significantly improved from T0 to T2. CONCLUSION: The present study demonstrated that cognitive-cycling DT training improves the motor functions, gait and cognitive performances of PD patients.

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Cognitive and motor dual task gait training exerted specific training effects on dual task gait performance in individuals with Parkinson’s disease: A randomized controlled pilot study

PLoS ONE ◽

10.1371/journal.pone.0218180 ◽

2019 ◽

Vol 14 (6) ◽

pp. e0218180 ◽

Cited By ~ 5

Author(s):

Yea-Ru Yang ◽

Shih-Jung Cheng ◽

Yu-Ju Lee ◽

Yan-Ci Liu ◽

Ray-Yau Wang

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Pilot Study ◽

Dual Task ◽

Gait Training ◽

Specific Training ◽

Training Effects ◽

Gait Performance ◽

Randomized Controlled

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173 EFFECTS OF STN-DBS ON THE DUAL TASK GAIT PERFORMANCE IN PATIENTS WITH PARKINSON'S DISEASE

Parkinsonism & Related Disorders ◽

10.1016/s1353-8020(10)70174-7 ◽

2010 ◽

Vol 16 ◽

pp. S50

Author(s):

T.-C. Kuo ◽

K.-D. Liu ◽

D.-E. Shan ◽

M.-W. Tsai ◽

S.-J. Lee

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Dual Task ◽

Gait Performance ◽

Stn Dbs

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The effects of aquatic physiotherapy on the gait of patients with Parkinson’s disease: a systematic review of the literature

10.5327/1516-3180.474 ◽

2021 ◽

Author(s):

Yuri Sena Melo ◽

Wesley Anderson de Souza Miranda ◽

João Lucas de Morais Bezerra ◽

Thaís Bel de Oliveira Teixeira

Keyword(s):

Systematic Review ◽

Parkinson’S Disease ◽

Parkinson's Disease ◽

Case Series ◽

Research Field ◽

Functional Mobility ◽

Control Group ◽

Systematic Review Methodology ◽

Gait Performance ◽

Gait Parameters

Introduction: Parkinson’s disease is a progressive and degenerative pathology that causes several motor impairments in gait. Aquatic physiotherapy has become an alternative, as it allows the training of gait, balance and muscle relaxation in a safe environment due to the physical properties of water. Objective: to verify the main effects of aquatic physiotherapy on gait rehabilitation in patients with Parkinson’s disease. Study design: This is a systematic review. Methodology: The research was carried out in four distinct stages. Being carried out in the following databases EBSCO, Pubmed, PEDro, Science Direct and MEDLINE; obeying the following inclusion criteria: individuals diagnosed with idiopathic Parkinson’s disease; who underwent aquatic physiotherapy with or without a control group and the main outcome was the improvement in gait performance. Case studies, case series, monograph, dissertation and articles without full access were excluded. The following keywords were used in the research field (“hydrotherapy” OR “aquatic exercise OR aquatic therapy”) AND Parkinson’s disease AND Gait. Results: Ten articles with good to regular methodological quality were included. Most of the results of the study were functional mobility, balance, pathology progression and gait parameters. Conclusion: it was observed that aquatic physiotherapy promoted good results in gait performance, mainly in balance, functional mobility and decreased motor signals, however there is still evidence about gait parameters.

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Cognitive and Motor Dual Task on Multi-area Brain Activation and Gait Performance in Individuals with Parkinson’s Disease

10.21203/rs.3.rs-258545/v1 ◽

2021 ◽

Author(s):

Yan-Ci Liu ◽

Yea-Ru Yang ◽

Nai-Chen Yeh ◽

Pei-Hsin Ku ◽

Chia-Feng Lu ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Dual Task ◽

Near Infrared ◽

Cognitive Task ◽

Premotor Cortex ◽

Brain Activation ◽

Functional Near Infrared Spectroscopy ◽

Gait Performance ◽

Walking Performance

Abstract Background In people with Parkinson’s disease (PD), gait performance deteriorating during dual task walking compared to single-task walking has been noted in previous studies. However, the effects of different types of dual task on gait performance and brain activation were still unknown. Methods This study investigated the walking performance changes and multi-area brain activities during cognitive and motor dual task walking in people with PD. Twenty-eight participants with PD were recruited and performed single walking (SW), walking while performing a cognitive task (WCT), and walking while performing a motor task (WMT) at their self-selected speed. Gait performance including walking speed, cadence, stride length, stride time, swing cycle, temporal and spatial variability and dual task cost (DTC) were recorded. Brain activation of the prefrontal cortex (PFC), premotor cortex (PMC), and supplementary motor areas (SMA) were measured by functional near-infrared spectroscopy during walking. Results Results showed the walking performance deteriorated upon performing a secondary task, especially the cognitive task. Also, a higher and sustained activation in PMC and SMA during WCT as compared with WMT and SW in the late phase of walking was found. Moreover, gait performance was negatively correlated with PMC and SMA activity during different walking tasks. Conclusions Individuals with PD demonstrated gait deterioration during dual task walking, especially WCT. The SMA and PMC were further activated in people with PD when performing cognitive dual task walking. Trial registrationTCTR20190118010. Registered 18 January 2019, retrospectively registered.

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