Evaluation of Antimicrobial effect of Triphala versus conventional root canal irrigants in primary teeth-An In vivo study

Objectives: The study aimed to evaluate and compare the antimicrobial efficacy of two root canal irrigantsOctenidine dihydrochloride and herbal Artemisia annua plant extract. Methods: Forty-two maxillary central incisors teeth were selected which were divided into four groups – group A (Octenidine dihydrochloride with saline), group B (only Octenidine dihydrochloride), group C (Artemisia annua with saline), group D (only Artemisia annua). Samples for microbiological culturing were collected after access preparation, after biomechanical preparation, and after final irrigation in each group with the help of paper points. CFU count was observed for both aerobic and anaerobic bacteria. The results were collected and subjected to a Student t-test. Results: After statistical analysis, it was observed that bacterial reduction was seen in all the groups but the maximum reduction was observed in group A. Conclusion: The results of the present study imply that a highly significant reduction in CFU/ml count was found in subgroup A1. Therefore, within the limitations of the present in-vivo study, Octenidine dihydrochloride can be recommended as an effective root canal irrigant than Artemisia annua plant extract.

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Radiographic examination of apical extrusion of root canal irrigants during cavitation induced by Er,Cr:YSGG laser irradiation: an in vivo study

Clinical Oral Investigations ◽

10.1007/s00784-012-0910-2 ◽

2012 ◽

Vol 17 (9) ◽

pp. 2105-2112 ◽

Cited By ~ 23

Author(s):

Harry Huiz Peeters ◽

Latief Mooduto

Keyword(s):

Laser Irradiation ◽

Root Canal ◽

In Vivo Study ◽

Radiographic Examination ◽

Root Canal Irrigants ◽

Apical Extrusion

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In vivo Evaluation of Antimicrobial Effect of Propolis, Miswak, Green Tea Compared to Sodium Hypochlorite and Chlorhexidine as Root Canal Irrigants in Necrotic Infected Single Rooted Teeth

Suez Canal University Medical Journal ◽

10.21608/scumj.2017.46987 ◽

2017 ◽

Vol 20 (1) ◽

pp. 53-61

Author(s):

Abeer Darag ◽

Dalia Fayyad ◽

Abd El Azeem El Gammal ◽

Ashraf Soliman

Keyword(s):

Green Tea ◽

Sodium Hypochlorite ◽

Root Canal ◽

Antimicrobial Effect ◽

In Vivo Evaluation ◽

Root Canal Irrigants

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An in Vivo Comparison of Antimicrobial Efficacy of Sodium Hypochlorite and Biopure MTAD™ against Enterococcus Faecalis in Primary Teeth: A qPCR Study

Journal of Clinical Pediatric Dentistry ◽

10.17796/jcpd.39.1.c4q2155r16817219 ◽

2014 ◽

Vol 39 (1) ◽

pp. 30-34 ◽

Cited By ~ 3

Author(s):

SG Tulsani ◽

N Chikkanarasaiah ◽

S Bethur

Keyword(s):

Root Canal ◽

Primary Teeth ◽

Antimicrobial Efficacy ◽

Permanent Teeth ◽

Control Group ◽

Statistical Significant Difference ◽

Anterior Teeth ◽

Significant Difference ◽

Root Canal Irrigant

Objectives: Biopure MTAD™, a new root canal irrigant has shown promising results against the most common resistant microorganism, E. faecalis, in permanent teeth. However, there is lack of studies comparing its antimicrobial effectiveness with NaOCl in primary teeth. The purpose of this study was to compare the in vivo antimicrobial efficacy of NaOCl 2.5% and Biopure MTAD™ against E. faecalis in primary teeth. Study design: Forty non vital single rooted primary maxillary anterior teeth of children aged 4-8 years, were irrigated either with NaOCl 2.5% (n=15), Biopure MTAD™ (n=15) and 0.9% Saline (n=10, control group). Paper point samples were collected at baseline (S1) and after chemomechanical preparation (S2) during the pulpectomy procedure. The presence of E. faecalis in S1 & S2 was evaluated using Real time Polymerase Chain Reaction. Results: Statistical significant difference was found in the antimicrobial efficacy of NaOCl 2.5 % and BioPure MTAD™ when compared to saline (p>0.05). However, no statistical significant difference was found between the efficacies of both the irrigants. Conclusions: NaOCl 2.5% and BioPure MTAD™, both irrigants are equally efficient against E. faecalis in necrotic primary anterior teeth. MTAD is a promising irrigant, however clinical studies are required to establish it as ideal root canal irrigant in clinical practice.

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Physicochemical and Biological Evaluation of Endodontic Filling Materials for Primary Teeth

Brazilian Dental Journal ◽

10.1590/0103-6440201701573 ◽

2017 ◽

Vol 28 (5) ◽

pp. 578-586 ◽

Cited By ~ 4

Author(s):

Katerine Jahnecke Pilownic ◽

Ana Paula Neutzling Gomes ◽

Zhe Jun Wang ◽

Luiza Helena Silva Almeida ◽

Ana Regina Romano ◽

...

Keyword(s):

Zinc Oxide ◽

Cell Viability ◽

Primary Teeth ◽

Antimicrobial Effect ◽

Biological Evaluation ◽

In Vivo Studies ◽

Filling Materials ◽

Histological Data ◽

Biocompatibility Test

Abstract This study assessed the pH, radiopacity, antimicrobial effect, cytotoxicity and biocompatibility of endodontic filling materials for primary teeth. Zinc oxide eugenol (ZOE), Vitapex and Calen paste thickened with zinc oxide (ZO) were evaluated in comparison to an experimental MTA-based material. Radiopacity was tested using a graduated aluminum stepwedge with a digital sensor (n=5). The materials pH was recorded at 1, 4, 12 h; 1, 3, 7, 15 and 30 days (n=5). Direct contact test was used to assess the antimicrobial efficacy against Enterococcus faecalis after 1, 4, 12, 24 h (n=5). Cytotoxicity assay used MTT test for cell viability after incubation for 1, 3 and 7 days (n=5). For biocompatibility test, Wistar rats had received implants containing each material (n=5). The biopsied tissues were histologically analyzed after 15, 30 and 60 days. The results of radiopacity, pH, antimicrobial capacity and cytotoxicity were analyzed using ANOVA and Tukey tests. The histological data were submitted to Kruskal-Wallis test. The experimental material presented the lowest radiopacity (3.28 mm Al) and had a pH>12.0 throughout the test period. The experimental material showed the highest antibacterial effect, killing over 99.97% bacteria in 4 h. Vitapex presented the highest cell viability. Initially, biocompatibility test showed moderate to severe inflammation in all groups. After 60 days, Calen+ZO group showed moderate inflammation, while the others showed predominantly mild inflammatory reaction. The present results demonstrated that the experimental MTA-based material exhibited satisfactory behavior regarding the studied properties. Additional in vivo studies are necessary for a better evaluation of the material.

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