Antimicrobial Efficacy of Octenidine Dihydrochloride and Artemisia Annua Plant Extract as Root Canal Irrigants – An In Vivo Study

2021 ◽  
Author(s):  
Tejinderpal Singh
Keyword(s):  
Plant Extract ◽  
Root Canal ◽  
Artemisia Annua ◽  
Saline Group ◽  
In Vivo Study ◽  
Antimicrobial Efficacy ◽  
Root Canal Irrigants ◽  
Octenidine Dihydrochloride ◽  
Group A

Objectives: The study aimed to evaluate and compare the antimicrobial efficacy of two root canal irrigantsOctenidine dihydrochloride and herbal Artemisia annua plant extract. Methods: Forty-two maxillary central incisors teeth were selected which were divided into four groups – group A (Octenidine dihydrochloride with saline), group B (only Octenidine dihydrochloride), group C (Artemisia annua with saline), group D (only Artemisia annua). Samples for microbiological culturing were collected after access preparation, after biomechanical preparation, and after final irrigation in each group with the help of paper points. CFU count was observed for both aerobic and anaerobic bacteria. The results were collected and subjected to a Student t-test. Results: After statistical analysis, it was observed that bacterial reduction was seen in all the groups but the maximum reduction was observed in group A. Conclusion: The results of the present study imply that a highly significant reduction in CFU/ml count was found in subgroup A1. Therefore, within the limitations of the present in-vivo study, Octenidine dihydrochloride can be recommended as an effective root canal irrigant than Artemisia annua plant extract.

Accuracy of Root ZX apex locator in primary teeth with different root canal irrigants: An in vivo study

2015 ◽  
Vol 3 (1) ◽  
pp. 24
Author(s):  
IE Neena ◽  
NM Roshan ◽  
R Basavanna ◽  
NB Nagaveni ◽  
P Poornima ◽  
...  
Keyword(s):  
Root Canal ◽  
Primary Teeth ◽  
In Vivo Study ◽  
Root Canal Irrigants

scholarly journals In vivo antimicrobial efficacy of 6% Morinda citrifolia, Azadirachta indica, and 3% sodium hypochlorite as root canal irrigants

2015 ◽  
Vol 09 (04) ◽  
pp. 529-534 ◽  
Author(s):  
Rajesh Podar ◽  
Gaurav P. Kulkarni ◽  
Shifali S. Dadu ◽  
Shraddha Singh ◽  
Shishir H. Singh
Keyword(s):  
Sodium Hypochlorite ◽  
Azadirachta Indica ◽  
Root Canal ◽  
Anaerobic Bacteria ◽  
Morinda Citrifolia ◽  
Antimicrobial Efficacy ◽  
Root Canal Irrigants ◽  
Aerobic And Anaerobic ◽  
Culture Sample

ABSTRACT Objective: To evaluate and compare the antimicrobial efficacy of 6% Morinda citrifolia, Azadirachta indica, and 3% sodium hypochlorite (NaOCl) as root canal irrigants. Materials and Methods: Thirty nonvital maxillary anteriors were randomly assigned to one of the three groups corresponding to the irrigant to be tested; 6% Morinda citrifolia juice (MCJ) (n = 10), A. indica (n = 10) and 3% NaOCl (n = 10). After the root canal access opening a root canal culture sample was taken with two paper points and cultured under aerobic and anaerobic conditions. Cleaning and shaping were completed with irrigation by 10 mL of respective irrigants and 5 mL of final rinse. The patients were recalled after 3 days and canals were rinsed again with 5 mL of the test irrigants. This was followed by obtaining a posttreatment root canal culture sample and culturing and analyzed by counting the colony forming units (CFUs). Results: Six percentage MCJ, A. indica, and 3% NaOCl showed a significant reduction (P < 0.05) in the mean CFU counts for aerobic and anaerobic bacteria between baseline and 3 days. Conclusion: There was no difference in the antimicrobial efficacy of 6% M. citrifolia, A. indica, and 3% NaOCl as root canal irrigants.

scholarly journals Comparative Evaluation of the Antimicrobial Efficacy of Octenidine Dihydrochloride with Contemporary Root Canal Disinfectants: A Systematic Review

2020 ◽  
pp. 64-76
Author(s):  
Rukhsaar Akbar Gulzar ◽  
P. Ajitha ◽  
Haripriya Subbaiyan
Keyword(s):  
Systematic Review ◽  
Root Canal ◽  
Primary Outcome Measure ◽  
Antimicrobial Efficacy ◽  
Antibacterial Efficacy ◽  
Human Teeth ◽  
Root Canal Irrigants ◽  
Octenidine Dihydrochloride ◽  
Wide Range

Octenidine is a cationic disinfectant that has been tested for its wide range of antibacterial efficacy and biocompatibility. It finds its application in the medical field as an antiseptic for wounds and mucous membranes. The present systematic review aims to compare the antimicrobial efficacy of Octenidine Dihydrochloride with various root canal irrigants and medicaments. An electronic search strategy was planned to search the database of PUBMED CENTRAL and MEDLINE using the search terms alone and in combination using PUBMED search builder till September 2019 for related studies. In Vitro studies that compared the antibacterial efficacy of Octenidine Dihydrochloride to other irrigants and medicaments against Enterococcus faecalis and Candida albicans using extracted human teeth were included in the review. The primary outcome measure was the reduction in the microbial load which was assessed through either CFU or the percentage of viable and dead bacteria. A total of 7 studies that matched the inclusion criteria were included in the systematic review. The studies indicated that Octenidine Dihydrochloride was highly effective in eliminating E faecalis and C albicans and could be a more biocompatible potential alternative or an adjunct to the existing irrigants and medicaments.

An in Vivo Comparison of Antimicrobial Efficacy of Sodium Hypochlorite and Biopure MTAD™ against Enterococcus Faecalis in Primary Teeth: A qPCR Study

2014 ◽  
Vol 39 (1) ◽  
pp. 30-34 ◽  
Author(s):  
SG Tulsani ◽  
N Chikkanarasaiah ◽  
S Bethur
Keyword(s):  
Root Canal ◽  
Primary Teeth ◽  
Antimicrobial Efficacy ◽  
Permanent Teeth ◽  
Control Group ◽  
Statistical Significant Difference ◽  
Anterior Teeth ◽  
Significant Difference ◽  
Root Canal Irrigant

Objectives: Biopure MTAD™, a new root canal irrigant has shown promising results against the most common resistant microorganism, E. faecalis, in permanent teeth. However, there is lack of studies comparing its antimicrobial effectiveness with NaOCl in primary teeth. The purpose of this study was to compare the in vivo antimicrobial efficacy of NaOCl 2.5% and Biopure MTAD™ against E. faecalis in primary teeth. Study design: Forty non vital single rooted primary maxillary anterior teeth of children aged 4-8 years, were irrigated either with NaOCl 2.5% (n=15), Biopure MTAD™ (n=15) and 0.9% Saline (n=10, control group). Paper point samples were collected at baseline (S1) and after chemomechanical preparation (S2) during the pulpectomy procedure. The presence of E. faecalis in S1 & S2 was evaluated using Real time Polymerase Chain Reaction. Results: Statistical significant difference was found in the antimicrobial efficacy of NaOCl 2.5 % and BioPure MTAD™ when compared to saline (p&gt;0.05). However, no statistical significant difference was found between the efficacies of both the irrigants. Conclusions: NaOCl 2.5% and BioPure MTAD™, both irrigants are equally efficient against E. faecalis in necrotic primary anterior teeth. MTAD is a promising irrigant, however clinical studies are required to establish it as ideal root canal irrigant in clinical practice.

Histological Changes Induced by CO2 Laser Microprobe Specially Designed for Root Canal Sterilization: In Vivo Study

1998 ◽  
Vol 16 (5) ◽  
pp. 263-267 ◽  
Author(s):  
GAVRIEL KESLER ◽  
RUMELIA KOREN ◽  
ANAT KESLER ◽  
NISSIM HAY ◽  
RIVKA GAL
Keyword(s):  
Co2 Laser ◽  
Root Canal ◽  
In Vivo Study ◽  
Histological Changes ◽  
Laser Microprobe
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