The Role of MRI in Breast Cancer Screening

2009 ◽  
Vol 7 (10) ◽  
pp. 1109-1115 ◽  
Author(s):  
Constance D. Lehman ◽  
Robert A. Smith

The 2009 NCCN Clinical Practice Guidelines in Oncology for Breast Cancer Screening and Diagnosis include significant updates for the role of MRI in screening women at increased risk for breast cancer. The NCCN now recommends considering breast MRI as an adjunct to annual mammography and clinical breast examination for women who have a BRCA1 or -2 mutation or who have a first-degree relative who has a BRCA1 or -2 mutation but who have not undergone genetic testing themselves; those who are determined to have a lifetime risk greater than 20% based on models that are highly dependent on family history; and those with a history of lobular carcinoma in situ. MRI is also recommended for patients who underwent radiation treatment to the chest between 10 and 30 years of age, and in those who carry or have a first-degree relative who carries a genetic mutation in the TP53 or PTEN genes (Li-Fraumeni, Cowden, and Bannahyan-Riley-Ruvalcaba syndromes). MRI is specifically not recommended for screening women at average risk for breast cancer. This article describes the peer-reviewed, published clinical research trials evaluating breast MRI in high-risk patients, on which the NCCN guidelines were based, and provides suggestions for future research.

2017 ◽  
Vol 35 (5_suppl) ◽  
pp. 232-232
Author(s):  
Jessica Trevino Jones ◽  
Kate Ida Lathrop ◽  
Michelle Janania Martinez ◽  
Uzair Mushtaq ◽  
Faraz Fiazuddin

232 Background: Research has established that woman with a history of lymphoma who receive chest wall radiation are at a greater risk to develop breast cancer. As such, recommendations for breast cancer screening for woman who received prior RT < 30yr of age have been a topic of discussions for the better part of 20 ears. Survivorship screening programs for our successfully treated hematologic malignancies should include referring survivors for breast cancer screening given their substantially increased risk of treatment related breast cancer. Methods: We investigated 88 patients who had lymphoma treated by radiation for lymphoma from 2016 to present time. We excluded 49 patients due to age, or not receiving chest wall radiation. For the 39 patients identified, further data included was the average amount of total grays received, if they were counselled about possibility of treatment related breast cancer, if they were Hispanic, and if they were referred for breast cancer screening/referred to specialty breast clinics. Results: We identified that all 39 patients in our study have not had any breast cancer screening despite being qualified to get breast MRI or mammogram. Less than 10% were advised of the possibility of treatment related breast cancer by radiation oncology per documentation. We have found that 48% of our patients are Hispanic, 7 patients’ records did not show total amount of grays received but 61% received greater than or equal to 30 grays. Conclusions: As our results showed that all 39 subjects were not properly screened to the best of our knowledge, we intervened because of our results. As a result, we plan on doing further quality care measures in our clinics to increase breast clinic referrals. Additionally, we are working on IRB approval to contact patients we have found needing screening to get screened appropriately. We are optimistic that our study will ensure future protocols for patients who received radiation to the chest, and look forward to presenting data as it becomes available.


2022 ◽  
pp. 104365962110668
Author(s):  
Cannas Kwok ◽  
Mi-Joung Lee ◽  
Chun Fan Lee

Introduction: Cultural beliefs are influential factors that affect breast cancer screening practices among Korean women. The aim of this study was to examine the role of educational levels and compare the cultural beliefs associated with breast cancer screening practices among immigrant Korean women in Australia with those of their counterparts in Korea. Methods: A secondary analysis based on data from convenience samples of 245 and 249 Korean women living in Australia and Korea, respectively. Data were collected by the Korean version of Breast Cancer Screening Beliefs Questionnaire. Results: Educational level has a significant association with Korean women’s cultural beliefs about breast cancer and breast cancer screening practices regardless of country of residence. Discussion: Nurses working in multicultural societies should take cultural beliefs and the role of education into account while designing strategies to promote breast cancer screening practices among immigrant Korean women.


2021 ◽  
Vol 10 (23) ◽  
pp. 5668
Author(s):  
Margaret Houser ◽  
David Barreto ◽  
Anita Mehta ◽  
Rachel F. Brem

Magnetic resonance imaging (MRI) is the most sensitive exam for detecting breast cancer. The American College of Radiology recommends women with 20% or greater lifetime risk of developing breast cancer be screened annually with MRI. However, other high-risk populations would also benefit. Hartmann et al. reported women with atypical hyperplasia have nearly a 30% incidence of breast cancer at 25-year follow-up. Women with dense breast tissue have up to a 4-fold increased risk of breast cancer when compared to average-risk women; their cancers are more likely to be mammographically occult. Because multiple cohorts of women are at high risk for developing breast cancer, there has been a movement to develop an abbreviated MRI (abMRI) protocol to expand the availability of MRI screening. Studies on abMRI effectiveness have been promising, with Weinstein et al. demonstrating a cancer detection rate of 27.4/1000 in women with dense breasts after a negative digital breast tomosynthesis. Breast MRI is also used to evaluate the extent of disease as part of preoperative assessment in women with newly diagnosed breast cancer, and to assess a patient’s response to neoadjuvant chemotherapy. This paper aims to explore the current uses of MRI and propose future indications and directions.


2012 ◽  
Author(s):  
Gerald Gartlehner ◽  
Kylie Thaler ◽  
Dominik Berzaczy ◽  
Angela Kaminski ◽  
Andrea Chapman ◽  
...  

2017 ◽  
Vol 14 (9) ◽  
pp. 1137-1143 ◽  
Author(s):  
Debra L. Monticciolo ◽  
Mary S. Newell ◽  
R. Edward Hendrick ◽  
Mark A. Helvie ◽  
Linda Moy ◽  
...  

2017 ◽  
pp. 1-10 ◽  
Author(s):  
Elizabeth J. Siembida ◽  
Archana Radhakrishnan ◽  
Sarah A. Nowak ◽  
Andrew M. Parker ◽  
Craig Evan Pollack

Purpose Physician reminders have successfully increased rates of mammography. However, considering recent changes to breast cancer screening guidelines that disagree on the optimal age to start and stop mammography screening, we sought to examine the extent to which reminders have been deployed for breast cancer screening targeting younger and older patients. Methods A mailed survey was sent to a national sample of 2,000 primary care physicians between May and September 2016. Physicians were asked whether they received reminders to screen women in various age groups (40 to 44, 45 to 49, and ≥ 75 years), the organizational screening guidelines they trusted most, and whether they recommended routine breast cancer screening to average-risk women in the different age groups. Using regression models, we assessed the association between reminders and physician screening recommendations, controlling for physician and practice characteristics, and evaluated whether the association varied by the guidelines they trusted. Results A total of 871 physicians responded (adjusted response rate, 52.3%). Overall, 28.9% of physicians reported receiving reminders for patient ages 40 to 44 years, 32.5% for patient ages 45 to 49 years, and 16.5% for patient ages ≥ 75 years. Receiving reminders significantly increased the likelihood of physicians recommending mammography screening. In adjusted analyses, 84% (95% CI, 77% to 90%) of physicians who received reminders recommended screening for women ages ≥ 75 versus 65% (95% CI, 62% to 69%) of those who did not receive reminders. The associations between reminders and screening recommendations remained consistent regardless of which guidelines physicians reported trusting. Conclusion Reminders were significantly associated with increases in physician screening recommendations for mammography, underscoring the need for careful implementation in scenarios where guidelines are discordant.


2019 ◽  
Vol 1 (2) ◽  
pp. 84-91
Author(s):  
Jonathan V Nguyen ◽  
Martha H Thomas

Abstract The majority of our hereditary breast cancer genes incur not only an increased risk for breast cancer but for other malignancies as well. Knowing whether an individual carries a pathogenic variant in a hereditary breast cancer gene can affect not only screening for the patient but for his or her family members as well. Identifying and appropriately testing individuals via multigene panels allows for risk reduction and early surveillance in at-risk individuals. Radiologists can serve as first-line identifiers of women who are at risk of having an inherited predisposition to breast cancer because they are interacting with all women receiving routine screening mammograms, and collecting family history suggestive of the presence of a mutation. We outline here the 11 genes associated with high breast cancer risk discussed in the National Comprehensive Cancer Network Genetic/Familial High-Risk: Breast and Ovarian (version 3.2019) as having additional breast cancer screening recommendations outside of annual mammography to serve as a guide for breast cancer screening and risk reduction, as well as recommendations for surveillance of nonbreast cancers.


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