scholarly journals Low mechanical ventilation times and reintubation rates associated with a specific weaning protocol in an intensive care unit setting: a retrospective study

Clinics ◽  
2012 ◽  
Vol 67 (9) ◽  
pp. 995-1000 ◽  
Author(s):  
CS Silva ◽  
KT Timenetsky ◽  
C Taniguchi ◽  
S Calegaro ◽  
CS Azevedo ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Retrospective Study ◽  
Intensive Care Unit Setting

Severe Complications of the Anterior Cricoid Split Operation and Single-Stage Laryngotracheoplasty

1994 ◽  
Vol 103 (9) ◽  
pp. 723-725 ◽  
Author(s):  
Anthony G. Zeitouni ◽  
John Manoukian
Keyword(s):  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Postoperative Complications ◽  
Postoperative Period ◽  
Intensive Care Unit Setting ◽  
Single Stage ◽  
Successful Outcome ◽  
Increased Risk ◽  
Split Operation

The management of congenital and acquired subglottic stenosis has been considerably facilitated with the introduction of the anterior cricoid split operation and, more recently, the single-stage laryngotracheoplasty. These procedures are followed by a 1- to 2-week period of sedation, during which the patient is paralyzed and completely dependent on mechanical ventilation. Although these procedures have proven very successful at achieving decannulation, the postoperative period can be the source of significant complications. This is illustrated with 4 cases of severe postoperative complications. The possible pathophysiologic causes are discussed, and the literature concerning the postoperative complications of these procedures is reviewed. The avoidance of neuromuscular blockade must be weighed against the possible increased need for narcotics and increased risk of self-extubation. An intensive care unit setting proficient in the care of these patients is necessary for a successful outcome.

Weaning Injured Patients with Prolonged Pulmonary Failure from Mechanical Ventilation in a Non-Intensive Care Unit Setting

2000 ◽  
Vol 49 (2) ◽  
pp. 224-231 ◽  
Author(s):  
Michael W. deBoisblanc ◽  
Robert K. Goldman ◽  
John C. Mayberry ◽  
Dawn M. Brand ◽  
Patrick D. Pangburn ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Intensive Care Unit Setting ◽  
Pulmonary Failure ◽  
Injured Patients

scholarly journals Early treatment of imported falciparum malaria in the intermediate and intensive care unit setting: an 8-year single-center retrospective study

Critical Care ◽  
2008 ◽  
Vol 12 (1) ◽  
pp. R22 ◽  
Author(s):  
Lukas Schwake ◽  
Judith P Streit ◽  
Lutz Edler ◽  
Jens Encke ◽  
Wolfgang Stremmel ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Retrospective Study ◽  
Falciparum Malaria ◽  
Early Treatment ◽  
Intensive Care Unit Setting ◽  
Single Center

scholarly journals Prognostic factors of adult tuberculous meningitis in intensive care unit: a single-center retrospective study in East China

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Baobao Feng ◽  
Xiao Fei ◽  
Ying Sun ◽  
Xingguo Zhang ◽  
Deya Shang ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Prognostic Factors ◽  
Retrospective Study ◽  
Tuberculous Meningitis ◽  
Adult Patients ◽  
Apache Ii ◽  
Cox Regression Analysis ◽  
Factors Associated

Abstract Background Tuberculous meningitis (TBM) is the most lethal form of tuberculosis worldwide. Data on critically ill TBM patients in the intensive care unit (ICU) of China are lacking. We tried to identify prognostic factors of adult TBM patients admitted to ICU in China. Methods We conducted a retrospective study on adult TBM in ICU between January 2008 and April 2018. Factors associated with unfavorable outcomes at 28 days were identified by logistic regression. Factors associated with 1-year mortality were studied by Cox proportional hazards modeling. Results Eighty adult patients diagnosed with TBM (age 38.5 (18–79) years, 45 (56 %) males) were included in the study. An unfavorable outcome was observed in 39 (49 %) patients and were independently associated with Acute Physiology and Chronic Health Evaluation (APACHE) II > 23 (adjusted odds ratio (aOR) 5.57, 95 % confidence interval (CI) 1.55–19.97), Sequential Organ Failure Assessment (SOFA) > 8 (aOR 9.74, 95 % CI 1.46–64.88), and mechanical ventilation (aOR 18.33, 95 % CI 3.15–106.80). Multivariate Cox regression analysis identified two factors associated with 1-year mortality: APACHE II > 23 (adjusted hazard ratio (aHR) 4.83; 95 % CI 2.21–10.55), and mechanical ventilation (aHR 9.71; 95 % CI 2.31–40.87). Conclusions For the most severe adult TBM patients of Medical Research Council (MRC) stage III, common clinical factors aren’t effective enough to predict outcomes. Our study demonstrates that the widely used APACHE II and SOFA scores on admission can be used to predict short-term outcomes, while APACHE II could also be used to predict long-term outcomes of adult patients with TBM in ICU.

scholarly journals Clinical Characteristics and Outcome of Critically Ill SARS-CoV-2 Patients Admitted to Intensive Care Unit of a Tertiary Care Hospital in North India: A Retrospective Study

2021 ◽  
Author(s):  
Reetu Verma ◽  
Rajeev Kumar Nishad ◽  
Rohit Patawa ◽  
Alok Kumar
Keyword(s):  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Retrospective Study ◽  
Critically Ill ◽  
Clinical Characteristics ◽  
Invasive Mechanical Ventilation ◽  
Age Groups ◽  
World Health ◽  
Comorbid Conditions

Introduction: World Health Organisation (WHO) declared the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outbreak a pandemic on 11 March 2020, due to the constantly increasing number of cases outside China. Previously, India had global record of highest single day spike of Corona Virus Disease-19 (COVID-19) cases, with 97,894 cases on 17thSeptember 2020. Aim: To find out the demographic and clinical characteristics of critically ill patients of SARS-CoV-2 and comparing the outcomes of patients admitted in COVID dedicated Intensive Care Unit (ICU) with and without co-morbidities and also in different age groups and sex. Material and Methods: This retrospective study from July 2020 to December 2020 was a single centre observational experience of management of COVID-19 patients at COVID dedicated ICU in Firozabad, India. The following data were recorded: age, sex, comorbidities and mode of oxygen delivery (invasive mechanical ventilation, non-invasive mechanical ventilation, high flow nasal canula). Chi-square test was used to compare the outcomes of patients admitted in COVID dedicated ICU with and without co-morbidities and also in different age groups and sex. Results: In this study, the data of 120 severely ill COVID-19 patients were reviewed. The mean age of patients were (58±15.29) years and male to female ratio was 3:1. At least one comorbid condition was reported in 53.3% of patients-most common being Hypertension (36.6%) followed by Diabetes mellitus 2 (20%), COPD (15%). Then Cardiovascular Diseases, Renal, Liver diseases and ailments followed. All patients admitted to COVID ICU had moderate to severe Acute Respiratory Distress Syndrome (ARDS). Older age (61 years and above, mortality 17%), male sex (16.7% deaths among 90 critically ill male COVID patients) and presence of comorbid conditions appear to have higher mortality in this study. However apart from comorbid conditions (p=0.001) none was statistically significant. The overall mortality in this study of 120 critically ill COVID patients was 14.16%. Conclusion: From this study, it can be suggested that survival of critically ill COVID patients can further be improved by better management of their comorbid conditions and avoiding complications of invasive ventilation. However, further multicentric studies with large sample size are needed to confirm these findings.

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