scholarly journals The analysis of patients under mechanical ventilation support in intensive care unit with the diagnosis of H1N1 infection: retrospective study

Author(s):  
Basak Altiparmak ◽  
Ali Uysal ◽  
Semra Demirbilek
BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Baobao Feng ◽  
Xiao Fei ◽  
Ying Sun ◽  
Xingguo Zhang ◽  
Deya Shang ◽  
...  

Abstract Background Tuberculous meningitis (TBM) is the most lethal form of tuberculosis worldwide. Data on critically ill TBM patients in the intensive care unit (ICU) of China are lacking. We tried to identify prognostic factors of adult TBM patients admitted to ICU in China. Methods We conducted a retrospective study on adult TBM in ICU between January 2008 and April 2018. Factors associated with unfavorable outcomes at 28 days were identified by logistic regression. Factors associated with 1-year mortality were studied by Cox proportional hazards modeling. Results Eighty adult patients diagnosed with TBM (age 38.5 (18–79) years, 45 (56 %) males) were included in the study. An unfavorable outcome was observed in 39 (49 %) patients and were independently associated with Acute Physiology and Chronic Health Evaluation (APACHE) II > 23 (adjusted odds ratio (aOR) 5.57, 95 % confidence interval (CI) 1.55–19.97), Sequential Organ Failure Assessment (SOFA) > 8 (aOR 9.74, 95 % CI 1.46–64.88), and mechanical ventilation (aOR 18.33, 95 % CI 3.15–106.80). Multivariate Cox regression analysis identified two factors associated with 1-year mortality: APACHE II > 23 (adjusted hazard ratio (aHR) 4.83; 95 % CI 2.21–10.55), and mechanical ventilation (aHR 9.71; 95 % CI 2.31–40.87). Conclusions For the most severe adult TBM patients of Medical Research Council (MRC) stage III, common clinical factors aren’t effective enough to predict outcomes. Our study demonstrates that the widely used APACHE II and SOFA scores on admission can be used to predict short-term outcomes, while APACHE II could also be used to predict long-term outcomes of adult patients with TBM in ICU.


2015 ◽  
Vol 12 (2) ◽  
pp. 881 ◽  
Author(s):  
Şebnem Çınar Yücel ◽  
İsmet Eser

<p class="Default"><strong>Purpose: </strong>This research is an experimental study (randomized controlled) which is carried out to investigate the effect on anxiety of hand massage and acupressure therapy in patients having mechanical ventilation support.</p><p><strong>Method and material: </strong>This randomized controlled research was conducted in Intensive care units of Ege University Faculty of Medicine, Department of Chest Diseases and Dr. Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital between the dates 18 June 2007 and 3 May 2008. The research sample was comprised of a total of 70 patients who met the research criteria in the hand massage and acupressure (n=35) and control (n =35) groups. Data were collected by using Patient Information Form, Patient Record Form and Visual Analogue Scale. It was following patients in experimental and control groups during seven days. It was recorded physiological indicators of anxiety, perceived anxiety and dyspnoea of patients in control group. These patients weren’t used hand massage and acupressure therapy. The patients in experimental group weren’t used hand massage and acupressure therapy in the first and seventh days. It was recorded physiological indicators of anxiety, perceived anxiety and dyspnoea. The other days, it was used hand massage and acupressure therapy. It was recorded physiological indicators of anxiety, perceived anxiety and dyspnoea This research is an experimental study (randomized controlled) which is carried out to investigate the effect on anxiety of hand massage and acupressure therapy in patients having mechanical ventilation support. Research was conducted in Intensive care units of Ege University Faculty of Medicine, Department of Chest Diseases and Dr. Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital between the dates 18 June 2007 and 3 May 2008. The research sample was comprised of a total of 70 patients who met the research criteria in the hand massage and acupressure (n=35) and control (n =35) groups. Data were collected by using Patient Information Form, Patient Record Form and Visual Analogue Scale. It was following patients in experimental and control groups during seven days. It was recorded physiological indicators of anxiety, perceived anxiety and dyspnoea of patients in control group. These patients weren’t used hand massage and acupressure therapy. The patients in experimental group weren’t used hand massage and acupressure therapy in the first and seventh days. It was recorded physiological indicators of anxiety, perceived anxiety and dyspnoea. The other days, it was used hand massage and acupressure therapy. Hand massage and acupressure therapy was limited to 18 minutes. It was recorded physiological indicators of anxiety, perceived anxiety and dyspnoea before and after hand massage and acupressure therapy. It was calculated intensive care unit costs and determined duration in intensive care unit after discharge of patients in experimental and control groups. In the data analysis were used chi square, repeated measures analysis of variance, independent samples t test, paired samples t test, LSD (Least-Significant difference) tests.</p><p class="Default"><strong>Results: </strong>According to the research findings, it wasn’t found significant as clinical which is the statistically significant difference in the physiological indicators of anxiety, perceived anxiety and dyspnoea except from oxygen saturation.</p><p><strong>Conclusion:</strong> In conclusion, our results suggest that hand massage and acupressure therapy might effectively relieve perceived dyspnoea and anxiety and reduce physiological indicators of anxiety in patients having mechanical ventilation support. The study provides a research-based intervention model for clinicians caring for MVP.</p>


2021 ◽  
pp. 79-82

Background: 5% of cases in COVID 19 disease require hospitalization in an intensive care unit. COVID -19 has a high mortality rate in the intensive care unit (ICU). There are many factors that affect this. There is no study on whether aging is one of these factors for intensive care patients. Objective: With this study, the data of critical geriatric and adult COVID-19 patients we followed up in the covid intensive care unit were evaluated and it was aimed to recognize the characteristics of critically ill patients. Material and Method: The files of 70 geriatric and 67 adult patients followed in the COVID-19 ICU were scanned and evaluated. Results: When evaluated in terms of developing organ dysfunction, cardiac arrhythmia was found to be statistically significant in adult patients (P=.01). 53 (75%) of 70 geriatric patients and 45 (67.1%) of 67 adult patients required invasive mechanical ventilation support. Intensive care mortality was 74.2% (52) in geriatric patients and 67.1% (45) in adult patients. There was no significant difference between the two groups in terms of mortality. Conclusion: It turned out that old age and being an adult are not important in terms of mortality in COVID-19 patients who need to be followed up in the intensive care unit.


Author(s):  
Reetu Verma ◽  
Rajeev Kumar Nishad ◽  
Rohit Patawa ◽  
Alok Kumar

Introduction: World Health Organisation (WHO) declared the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outbreak a pandemic on 11 March 2020, due to the constantly increasing number of cases outside China. Previously, India had global record of highest single day spike of Corona Virus Disease-19 (COVID-19) cases, with 97,894 cases on 17thSeptember 2020. Aim: To find out the demographic and clinical characteristics of critically ill patients of SARS-CoV-2 and comparing the outcomes of patients admitted in COVID dedicated Intensive Care Unit (ICU) with and without co-morbidities and also in different age groups and sex. Material and Methods: This retrospective study from July 2020 to December 2020 was a single centre observational experience of management of COVID-19 patients at COVID dedicated ICU in Firozabad, India. The following data were recorded: age, sex, comorbidities and mode of oxygen delivery (invasive mechanical ventilation, non-invasive mechanical ventilation, high flow nasal canula). Chi-square test was used to compare the outcomes of patients admitted in COVID dedicated ICU with and without co-morbidities and also in different age groups and sex. Results: In this study, the data of 120 severely ill COVID-19 patients were reviewed. The mean age of patients were (58±15.29) years and male to female ratio was 3:1. At least one comorbid condition was reported in 53.3% of patients-most common being Hypertension (36.6%) followed by Diabetes mellitus 2 (20%), COPD (15%). Then Cardiovascular Diseases, Renal, Liver diseases and ailments followed. All patients admitted to COVID ICU had moderate to severe Acute Respiratory Distress Syndrome (ARDS). Older age (61 years and above, mortality 17%), male sex (16.7% deaths among 90 critically ill male COVID patients) and presence of comorbid conditions appear to have higher mortality in this study. However apart from comorbid conditions (p=0.001) none was statistically significant. The overall mortality in this study of 120 critically ill COVID patients was 14.16%. Conclusion: From this study, it can be suggested that survival of critically ill COVID patients can further be improved by better management of their comorbid conditions and avoiding complications of invasive ventilation. However, further multicentric studies with large sample size are needed to confirm these findings.


2020 ◽  
Vol 7 (6) ◽  
pp. 532-534
Author(s):  
Orhan Binici ◽  
Evren Büyükfırat ◽  
Erdoğan Duran ◽  
Veli Fahri Pehlivan ◽  
Ahmet Atlas ◽  
...  

Objective: Intoxication cases are increasing in societies day by day. Intoxication cases are followed-up and treated in Intensive Care Units (ICU). In our study, the intoxication cases followed in the intensive care unit; it is aimed to evaluate demographic data, prognosis, causing agents, mortality rates retrospectively. Material and Methods: In the intensive care unit between the dates of January 1, 2016 and March 10, 2020, the patients who were admitted with the diagnosis of acute intoxication, age, gender, the drug is taken for poisoning or the substance they are exposed to, Glasgow Coma Scale (GCS), the number of days hospitalized, mechanical ventilation support day and the number and mortality status were evaluated retrospectively. Results: The 88 patients applied to ICU with the diagnosis of acute intoxication, 55(62%)  of them are female and 33(37%) of them are male. According to all gender data, the intoxication was found to be the highest between the ages of 17 and 30 (n: 69) and the least under 17 age (n: 2). Half of the patients (n: 44 50%) were treated in less than 2 days. With a single drug, intoxication was seen as the highest with antidepressants. Conclusion: Intoxications occur mostly with medications and among these drugs, they are mostly seen with anti-depressive medications for psychiatric treatment. When treatment is started quickly after the poisoning, the duration of hospital stay is shortened and the prognosis is better. Since poisoning varieties differ by region, this information should be known and updated by the people who treat it.


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