scholarly journals Blood Components Involving Acceleration of Erythrocyte Sedimentation Rate, Particularly Red Cell Shape Factors.

2001 ◽  
Vol 28 (3) ◽  
pp. 311-321
Author(s):  
Akira FUROTA
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Cell Shape ◽  
Red Cell ◽  
Blood Components ◽  
Shape Factors ◽  
Erythrocyte Sedimentation ◽  
Red Cell Shape

Increased Erythrocyte Sedimentation Rate Probably Due to a Red Cell Factor

2009 ◽  
Vol 6 (6) ◽  
pp. 427-430 ◽  
Author(s):  
H. Heistö ◽  
H. C. Godal ◽  
K. A. Gröttum ◽  
Grethe Madsen ◽  
Björg Uggerud>
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Red Cell ◽  
Erythrocyte Sedimentation

scholarly journals Correlation between Procalcitonin, Erythrocyte Sedimentation Rate and Red-Cell Distribution Width with Outcomes in ALL

2021 ◽  
Vol 27 (3) ◽  
pp. 276
Author(s):  
Nathalya Dwi Kartikasari ◽  
I. G.A.A Putri Sri Rejeki ◽  
I Dewa Gede Ugrasena
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Kinetic Method ◽  
Red Cell Distribution Width ◽  
Induction Phase ◽  
Red Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
Erythrocyte Sedimentation ◽  
Poor Outcomes

Acute Lymphoblastic Leukemia (ALL) increases annually and the incidence is mostly found in children. Its high failure rate is due to infection in the induction phase of chemotherapy. One of the strategies is laboratory testing to determine prognostic factors or predictors that can help clinicians determine therapy and outcomes in ALL. Research related to Procalcitonin (PCT), Erythrocyte Sedimentation Rate (ESR), and Red-cell Distribution Width (RDW) test in ALL children with poor outcomes has never been performed at Dr. Soetomo Hospital, Surabaya. This study aimed to determine the correlation of some infection parameters (PCT, ESR, and RDW) with outcomes in ALL. This was a cross-sectional study in the Pediatric Ward of the Dr. Soetomo Hospital in the period of June-August 2019. A total of 34 ALL patients after the induction phase of chemotherapy according to ALL-2018 protocol were included in this research. Procalcitonin, ESR, and RDW were determined using an ELFA method, photometrical capillary stopped-flow kinetic method, and flow cytometry method. The age of the study subjects ranged from 3 months to 16 years old, 32 patients (94.1%) were categorized as ALL-L1, 23 patients (67.6%) used protocol of high-risk group stratification. The study subjects were divided into 10 patients with poor outcomes and 24 patients with a good outcome. Procalcitonin was (2.66±13.15), ESR was (22.65±19.18), and RDW was (14.97±2.727). There was a significant correlation between PCT and outcomes.

scholarly journals The Erythrocyte Sedimentation Rate and Its Relation to Cell Shape and Rigidity of Red Blood Cells from Chorea-Acanthocytosis Patients in an Off-Label Treatment with Dasatinib

Biomolecules ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 727
Author(s):  
Antonia Rabe ◽  
Alexander Kihm ◽  
Alexis Darras ◽  
Kevin Peikert ◽  
Greta Simionato ◽  
...  
Keyword(s):  
Mathematical Modeling ◽  
Red Blood Cells ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Blood Cells ◽  
Cell Shape ◽  
Healthy Controls ◽  
Off Label ◽  
Erythrocyte Sedimentation ◽  
Hematology Parameters

Background: Chorea-acanthocytosis (ChAc) is a rare hereditary neurodegenerative disease with deformed red blood cells (RBCs), so-called acanthocytes, as a typical marker of the disease. Erythrocyte sedimentation rate (ESR) was recently proposed as a diagnostic biomarker. To date, there is no treatment option for affected patients, but promising therapy candidates, such as dasatinib, a Lyn-kinase inhibitor, have been identified. Methods: RBCs of two ChAc patients during and after dasatinib treatment were characterized by the ESR, clinical hematology parameters and the 3D shape classification in stasis based on an artificial neural network. Furthermore, mathematical modeling was performed to understand the contribution of cell morphology and cell rigidity to the ESR. Microfluidic measurements were used to compare the RBC rigidity between ChAc patients and healthy controls. Results: The mechano-morphological characterization of RBCs from two ChAc patients in an off-label treatment with dasatinib revealed differences in the ESR and the acanthocyte count during and after the treatment period, which could not directly be related to each other. Clinical hematology parameters were in the normal range. Mathematical modeling indicated that RBC rigidity is more important for delayed ESR than cell shape. Microfluidic experiments confirmed a higher rigidity in the normocytes of ChAc patients compared to healthy controls. Conclusions: The results increase our understanding of the role of acanthocytes and their associated properties in the ESR, but the data are too sparse to answer the question of whether the ESR is a suitable biomarker for treatment success, whereas a correlation between hematological and neuronal phenotype is still subject to verification.

Correlations between Platelet Parameters and Erythrocyte Sedimentation Rate

2004 ◽  
Vol 10 (2) ◽  
pp. 121-121
Author(s):  
Atchasai Siritantikorn ◽  
Viroj Wiwanitkit
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Erythrocyte Sedimentation

Prognostic Value of Erythrocyte Sedimentation Rate in Patients with Colorectal Cancer

2008 ◽  
Vol 24 (5) ◽  
pp. 351
Author(s):  
Young Ki Kim ◽  
Seong Woo Hong ◽  
Jung Woo Chun ◽  
Yeo Goo Chang ◽  
In Wook Paik ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Prognostic Value ◽  
Erythrocyte Sedimentation
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