scholarly journals La misura della qualità di vita e dell’utilità in farmacoeconomia: strumenti e loro applicazioni in una rassegna di letteratura

2002 ◽  
Vol 3 (4) ◽  
pp. 241-252
Author(s):  
Ya-Ting Chan
Keyword(s):  
Quality Of Life ◽  
Economic Evaluation ◽  
Cost Utility ◽  
Economic Evaluations ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Cost ◽  
The Relationship

In a climate of economic scarcity, decisions about the allocation of healthcare resources need to be made explicit. An economic evaluation is able to identify and quantify the relationship between an input of resources and an output, hence to appreciate the efficiency of the project. One of the recent methodological approaches that has been used increasingly in health economic evaluations is the ‘cost-utility analysis’ (CUA). CUA considers benefits in utility terms and uses a unique index to assess them. We investigated the generic measurements of health related quality of life in the economic evaluation. Different instruments for evaluating quality of life and utility were categorized and briefly introduced. Literatures published in the journal “PharmacoEconomics” in 1997-2001 regarding quality of life and utility were reviewed. We were especially interested in the application of health profile SF-36 and utility measure EQ-5D. Selected articles were further analyzed and some issues concerning the methodologies of quality of life and utility are discussed.

scholarly journals The Relationship Between Health-Related Quality of Life and Anabolic Hormone Levels in Middle-Aged and Elderly Men With Prediabetes: A Cross-Sectional Study

2018 ◽  
Vol 12 (5) ◽  
pp. 1593-1603
Author(s):  
Michał Rabijewski ◽  
Lucyna Papierska ◽  
Radosław Maksym ◽  
Ryszard Tomasiuk ◽  
Anna Kajdy ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Free Testosterone ◽  
Control Group ◽  
Middle Aged ◽  
Elderly Men ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Relationship

The aim of this study was to compare health-related quality of life (HRQoL) between men with prediabetes (PD) and a control group as well as to investigate the relationship between HRQoL and anabolic hormones. The analysis was carried out in 176 middle-aged (40–59 years) and elderly (60 80 years) men with PD, and 184 control peers. PD was defined according the American Diabetes Association and HRQoL was assessed by the SF-36 questionnaire. Total testosterone (TT), calculated free testosterone, dehydroepiandrosterone sulfate (DHEAS), and insulin-like growth factor 1 (IGF-1) were measured. Analysis of the standardized physical and mental component summary scores (SF-36p and SF-36m) revealed that patients with PD had lower SF-36p and SF-36m than control group ( p < .02 and p < .001). Middle-aged men with PD had lower SF-36p and SF-36m than control peers, whereas elderly men with PD had lower only SF-36p. In men with PD negative correlations between glycated hemoglobin (HbA1c) and SF-35m score ( r = −0.3768; p = .02) and between HbA1c and SF-36p score ( r = −0.3453; p = .01) were reported. In middle-aged prediabetic men, SF-36p was associated with high free testosterone and low HbA1c while SF-36m with high TT and high DHEAS. In elderly patients with PD, SF-36p was associated with high TT, high IGF-1, and low HbA1c, while SF-36m correlated with high free testosterone and high DHEAS. In conclusion, PD in men is associated with decreased HRQoL in comparison with healthy men, and generally better quality of life is associated with higher testosterone, higher free testosterone, higher DHEAS, and lower HbA1c.

Health-Related Quality of Life and Cost–Utility Analysis of Employees With Musculoskeletal Disorders Receiving Vocational Physiotherapy

2020 ◽  
Vol 68 (10) ◽  
pp. 476-479
Author(s):  
Laran Chetty
Keyword(s):  
Quality Of Life ◽  
Musculoskeletal Disorders ◽  
Cost Utility ◽  
Cost Utility Analysis ◽  
Health Related Quality ◽  
Utility Analysis ◽  
Related Quality ◽  
Health Related ◽  
The Cost

Background: The purpose of this project was to evaluate both health-related quality of life (HRQoL) and cost-utility associated with care for employees with musculoskeletal disorders who received vocational physiotherapy at a North London National Health Service (NHS) Foundation Trust in the United Kingdom. Methods: A pre- and post-physiotherapy EuroQol 5 Dimension (EQ-5D) questionnaire was administered to employees presenting to the vocational physiotherapy service (VPS) with musculoskeletal disorders. The cost-utility analysis of the physiotherapy service was calculated using cost data provided by VPS billing information and benefits measured using Quality-Adjusted Life Years (QALYs). Findings: Overall, there was a significant improvement in the EQ-5D index from baseline to discharge in all HRQoL domains. The visual analog scale (VAS) improved from a mean of 31.5 (SD = 18.3) at baseline to 73.2 (SD = 18.5) at discharge. A cost-utility analysis indicated that the VPS would continue to be cost-effective until the cost per employee increased by 82.5%. Conclusion/Application to Practice: The project supports integration of vocational physiotherapy services into an occupational health department.

scholarly journals The impact of poor medication knowledge on health-related quality of life in people with Parkinson’s disease: a mediation analysis

2021 ◽  
Author(s):  
Hannah M. Zipprich ◽  
Sarah Mendorf ◽  
Aline Schönenberg ◽  
Tino Prell
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Assessment ◽  
Medication Knowledge ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Relationship

Abstract Purpose This study aimed to determine how limited medication knowledge as one aspect of health literacy contributes to poorer health-related quality of life (HRQoL) in people with Parkinson’s disease (PD). Methods Demographical data, PD-specific data (MDS-Unified Parkinson’s Disease-Rating Scale, Nonmotor symptom scale), and data about depressive symptoms (Beck’s depression inventory), cognition (Montreal cognitive assessment), HRQoL (Short-Form Health Questionnaire-36, SF-36), and medication knowledge (names, time of taking, indication, dosage) were assessed in 193 patients with PD. Multivariate analysis of variance (MANOVA), multivariate analysis of covariance, and mediation analyses were used to study the relationship between medication knowledge and HRQoL in combination with different mediators and covariates. Results Overall, 43.5% patients showed deficits in at least one of the 4 knowledge items, which was associated with higher age, number of medications per day and depression level, and poorer cognitive function, motor function, and lower education level. Using one-way MANOVA, we identified that medication knowledge significantly impacts physical functioning, social functioning, role limitations due to physical problems, and role limitations due to emotional problems. Mediation models using age, education level, and gender as covariates showed that the relationship between knowledge and SF-36 domains was fully mediated by Beck’s Depression Inventory but not by Montreal Cognitive Assessment. Conclusions Patients who expressed unawareness of their medication did not necessarily have cognitive deficits; however, depressive symptoms may instead be present. This concomitant depressive symptomatology is crucial in explaining the contribution of nonadherence and decreased medication knowledge to poor quality of life.

scholarly journals Developing a preference-based measure for weight-specific health-related quality of life in adolescence: the WAItE UK valuation study protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. e054203
Author(s):  
Tomos Robinson ◽  
Sarah Hill ◽  
Yemi Oluboyede
Keyword(s):  
Quality Of Life ◽  
Economic Evaluation ◽  
Economic Evaluations ◽  
Health Related Quality ◽  
Health States ◽  
Related Quality ◽  
Health Related ◽  
The Uk ◽  
Specific Health

IntroductionAdolescent obesity is a public health problem in the UK. The Weight-Specific Adolescent Instrument for Economic Evaluation (WAItE) has been developed as the first weight-specific health-related quality of life measure appropriate for economic evaluation, but currently cannot be used to generate quality-adjusted life years (QALYs), which are the basis of cost-utility analysis. Generic measures (such as the EQ-5D-Y or CHU-9D) may be insensitive to small but important health changes in overweight or obese adolescents. This study aims to generate a preference-based scoring algorithm for the WAItE.Methods and analysisA discrete choice experiment (DCE) will be administered to value health states described by the WAItE classification system. These health states will be presented to members of the adult general population of the UK via an online survey. A range of regression models will be used to produce the utility algorithm for the WAItE. The DCE-visual analogue scale and time trade-off (TTO) anchoring methods will be used anchor the value set on to the 0–1 QALY scale.Ethics and disseminationThe Newcastle University Medical School Ethics Committee approved the study (references 4772/2020 (DCE) and 9978/2020 (TTO)). The developed algorithm can be applied to future economic evaluations of weight management interventions and treatments for adolescents.

Leisure Lifestyle and Health-Related Quality of Life of Taiwanese Adults

2012 ◽  
Vol 40 (2) ◽  
pp. 301-317 ◽  
Author(s):  
Ming-Ching Yang ◽  
Jen-Son Cheng ◽  
Shu-Wen Yu
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Health Related Quality ◽  
Short Form Health Survey ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Relationship ◽  
Short Form Health

The relationship between various leisure lifestyles (LLS) and health-related quality of life (HRQoL) was analyzed. The 36-Item Short-Form Health Survey (SF-36; Ware, Kosinski, & Keller, 1994) was completed by 622 residents of Taiwan. Factor analysis resulted in 6 dimensions of leisure lifestyle: preferred travel, self-realization, morning action, exercise loving, homebody, and social support. The scores for self-realization were the highest and the scores for morning action the lowest. Cluster analysis was applied to categorize the respondents into 4 leisure lifestyle groups: morning exercisers, traveling and social people, static recreation people, and active exercisers. In general, those groups of people for whom their LLS included more exercise had a better HRQoL.

The role of clinical pharmacist in enhancing the health-related quality of life in patients with pulmonary tuberculosis

2020 ◽  
Vol 10 (4) ◽  
Author(s):  
Eldhose Varghese ◽  
Irrin Poulose ◽  
Chaitanya Sagar G ◽  
Jennifer Ann Jose ◽  
Mintu Mathew Ms
Keyword(s):  
Quality Of Life ◽  
Pulmonary Tuberculosis ◽  
Patient Information ◽  
Patient Information Leaflet ◽  
Information Leaflet ◽  
Patient Counselling ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Tuberculosis (TB) is potentially airborne severe infectious disease which requires long term treatment. It considerably affects the physical and mental health quality of the patient’s life. Appropriate patient counselling with the help of Patient Information Leaflet will help to improve the patient’s quality of life and overall treatment outcome. To enhance the health related quality of life in pulmonary tuberculosis patients by providing patient counselling with the aid of patient information leaflet. An interventional study was carried out for six months in 80 patients diagnosed with pulmonary tuberculosis from the OP & IP of Tuberculosis and Chest Department of a medical college hospital. The HRQoL was assessed using the SF-36 questionnaire. Appropriate patient counselling was provided with the help of Patient Information Leaflet. In our study, a total of 80 patients were enrolled, out of which 49[61%] were Out-patients, and 31[39%] were In-patients. All the 8 sub domains of the SF-36 survey show statistical significance with improvement in 2nd Visit (after counselling) when compared with the baseline visit. The demographic variables like smoking, low socioeconomic status, allergies, family history show statistically significant association with overall HRQoL. The HRQOL of the pulmonary tuberculosis patients were initially low before the start of Anti-TB therapy, after providing proper patient counselling using patient information leaflet the HRQoL scores were found to be increased on the subsequent re-visits, which implies the need of proper patient counselling and follow-up in PTB for the better quality of life.

scholarly journals Correction to: The relationship between comorbidity medication adherence and health related quality of life among patients with cancer

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Dana Drzayich Antol ◽  
Adrianne Waldman Casebeer ◽  
Raya Khoury ◽  
Todd Michael ◽  
Andrew Renda ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Medication Adherence ◽  
Health Related Quality ◽  
Patients With Cancer ◽  
Related Quality ◽  
Health Related ◽  
The Relationship

An amendment to this paper has been published and can be accessed via the original article.

Perceived neighbourhood safety moderates the relationship between active school travel and health-related quality of life

2021 ◽  
Vol 70 ◽  
pp. 102623
Author(s):  
Gina Martin ◽  
Megan Graat ◽  
Alina Medeiros ◽  
Andrew F. Clark ◽  
Brenton L.G. Button ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Related Quality ◽  
School Travel ◽  
Active School Travel ◽  
Related Quality ◽  
Health Related ◽  
The Relationship
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