scholarly journals The Relationship Between Health-Related Quality of Life and Anabolic Hormone Levels in Middle-Aged and Elderly Men With Prediabetes: A Cross-Sectional Study

2018 ◽  
Vol 12 (5) ◽  
pp. 1593-1603
Author(s):  
Michał Rabijewski ◽  
Lucyna Papierska ◽  
Radosław Maksym ◽  
Ryszard Tomasiuk ◽  
Anna Kajdy ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Free Testosterone ◽  
Control Group ◽  
Middle Aged ◽  
Elderly Men ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Relationship

The aim of this study was to compare health-related quality of life (HRQoL) between men with prediabetes (PD) and a control group as well as to investigate the relationship between HRQoL and anabolic hormones. The analysis was carried out in 176 middle-aged (40–59 years) and elderly (60 80 years) men with PD, and 184 control peers. PD was defined according the American Diabetes Association and HRQoL was assessed by the SF-36 questionnaire. Total testosterone (TT), calculated free testosterone, dehydroepiandrosterone sulfate (DHEAS), and insulin-like growth factor 1 (IGF-1) were measured. Analysis of the standardized physical and mental component summary scores (SF-36p and SF-36m) revealed that patients with PD had lower SF-36p and SF-36m than control group ( p < .02 and p < .001). Middle-aged men with PD had lower SF-36p and SF-36m than control peers, whereas elderly men with PD had lower only SF-36p. In men with PD negative correlations between glycated hemoglobin (HbA1c) and SF-35m score ( r = −0.3768; p = .02) and between HbA1c and SF-36p score ( r = −0.3453; p = .01) were reported. In middle-aged prediabetic men, SF-36p was associated with high free testosterone and low HbA1c while SF-36m with high TT and high DHEAS. In elderly patients with PD, SF-36p was associated with high TT, high IGF-1, and low HbA1c, while SF-36m correlated with high free testosterone and high DHEAS. In conclusion, PD in men is associated with decreased HRQoL in comparison with healthy men, and generally better quality of life is associated with higher testosterone, higher free testosterone, higher DHEAS, and lower HbA1c.

Abstract 2090: Health Related Quality of Life Outcomes of Therapeutic Life Style Modification Program for Women with Metabolic Syndrome

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Eui Geum Oh ◽  
Soo Hyun Kim ◽  
So Yeon Bang ◽  
Sa Saeng Hyun ◽  
Yong Kwan Jeon ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Metabolic Syndrome ◽  
General Health ◽  
Control Group ◽  
Health Related Quality ◽  
Point Change ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Background: The metabolic syndrome (MetS), with associated increased CHD risk, is highly prevalent among postmenopausal women in Korea. Although therapeutic lifestyle modification (TLM) has been recommended as a cornerstone therapy, studies investigating the effects of TLM on health related quality of life (HRQOL) are limited. Purpose : This study was to evaluate HRQOL outcomes of a six-month TLM in Korean women with Mets. Methods: A randomized controlled design was used. Fifty four women (mean age of 63.2 y) with Mets were recruited from community health centers and randomly assigned to the intervention (N=31) or control (N=23) groups. The subjects in the intervention group participated in a supervised weekly TLM session for six months. The TLM program was consisted of health monitoring, education, aerobic exercise (40-min/session, 200 Kcal/day), and a low calorie diet with low carbohydrate (≈1300Kcal/d). Those in the control group received a booklet about MetS and were instructed to maintain their usual diet and activities. HRQOL was measured using the MOS SF-36 at before, during (month 3), completion (month 6), and after completion of the TLM program (month 12). Mixed-model repeated measures ANCOVA was used to evaluate HRQOL outcomes. Results : There were significant group by time interactions for general health ( P = .043) and vitality ( P = .012). Both general health (mean 23-point change) and vitality scores (mean 16-point change) greatly improved in the treatment group over 6 months of TLM, compared with control group. However, the improvement of the general health and vitality in the experimental group was not sustained at month 12. There were significant treatment main effects (all P < .05) for the remaining SF-36 subscale scores. Conclusion : A systematic TLM program may be effective strategy for improving HRQOL in postmenopausal women with MetS.

scholarly journals Urinary incontinence in the puerperium and its impact on the health-related quality of life

2012 ◽  
Vol 20 (2) ◽  
pp. 346-353 ◽  
Author(s):  
Lígia da Silva Leroy ◽  
Maria Helena Baena de Moraes Lopes
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Short Form ◽  
Control Group ◽  
Case Group ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

This case-control study evaluated whether UI in the puerperium compromises the health-related quality of life (HRQoL) and if so, in which aspects. The study included 344 women (77 case group and 267 control group) up to 90 days postpartum, who were attended the Obstetrics Outpatient Clinic of a public teaching hospital, for the postpartum follow up consultation. A socio-demographic and clinical data questionnaire formulated and validated for the study, the International Consultation on Incontinence Questionnaire - Short-Form (ICIQ-SF), the King's Health Questionnaire (KHQ) and the Medical Outcomes Study 36 - Item Short Form Health Survey (SF-36), were applied. The mean score of the ICIQ-SF was 13.9 (SD: 3.7). The case group presented high mean scores in the domains Impact of the Incontinence, Emotions, Daily Activity Limitations and Physical Limitations, of the KHQ. The groups differed significantly in the domains Physical Aspects, Pain, General Health Status, Vitality, Social Aspects and Mental Health of the SF-36. It is concluded that UI significantly affects the physical and mental health of puerperae.

scholarly journals The impact of poor medication knowledge on health-related quality of life in people with Parkinson’s disease: a mediation analysis

2021 ◽  
Author(s):  
Hannah M. Zipprich ◽  
Sarah Mendorf ◽  
Aline Schönenberg ◽  
Tino Prell
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Assessment ◽  
Medication Knowledge ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Relationship

Abstract Purpose This study aimed to determine how limited medication knowledge as one aspect of health literacy contributes to poorer health-related quality of life (HRQoL) in people with Parkinson’s disease (PD). Methods Demographical data, PD-specific data (MDS-Unified Parkinson’s Disease-Rating Scale, Nonmotor symptom scale), and data about depressive symptoms (Beck’s depression inventory), cognition (Montreal cognitive assessment), HRQoL (Short-Form Health Questionnaire-36, SF-36), and medication knowledge (names, time of taking, indication, dosage) were assessed in 193 patients with PD. Multivariate analysis of variance (MANOVA), multivariate analysis of covariance, and mediation analyses were used to study the relationship between medication knowledge and HRQoL in combination with different mediators and covariates. Results Overall, 43.5% patients showed deficits in at least one of the 4 knowledge items, which was associated with higher age, number of medications per day and depression level, and poorer cognitive function, motor function, and lower education level. Using one-way MANOVA, we identified that medication knowledge significantly impacts physical functioning, social functioning, role limitations due to physical problems, and role limitations due to emotional problems. Mediation models using age, education level, and gender as covariates showed that the relationship between knowledge and SF-36 domains was fully mediated by Beck’s Depression Inventory but not by Montreal Cognitive Assessment. Conclusions Patients who expressed unawareness of their medication did not necessarily have cognitive deficits; however, depressive symptoms may instead be present. This concomitant depressive symptomatology is crucial in explaining the contribution of nonadherence and decreased medication knowledge to poor quality of life.

scholarly journals The effect of obesity upon Health Related Quality of Life (HRQoL): A comparison of the AQoL-8D and SF-36 instruments

2012 ◽  
Vol 13 (2) ◽  
pp. 69-82 ◽  
Author(s):  
Munir Ahmed Khan ◽  
Jeff Richardson ◽  
Paul O'Brien
Keyword(s):  
Quality Of Life ◽  
Content Validity ◽  
Overweight And Obesity ◽  
Control Group ◽  
Health Related Quality ◽  
Life Years ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

OBJECTIVES: The objective of this study was to describe and measure the loss of health related quality of life (HRQoL) associated with obesity using two generic instruments. The first of these, the SF-36, is the most widely used and validated HRQoL instrument worldwide. However, it does not provide utility weights and cannot be used to measure quality adjusted life years (QALYs), an increasingly common unit for comparing the effect of health states in economic evaluation studies. The second, the AQoL-8D, is a multi-attribute utility (MAU) instrument which was developed to increase sensitivity of previous MAU instruments to psycho-social dimensions of a health state and to allow the calculation of QALYs. Since the two instruments differ, an important additional objective of the study was to determine the validity of the AQoL-8D as judged by the SF-36, and therefore the confidence which might be placed upon its use in the context of obesity.METHODS: Data were obtained from patients waiting for bariatric surgery who had completed both the SF-36 and AQoL-8D quality of life instruments and a general questionnaire including height, weight, demographic and socio-economic information. For comparative purposes, scores were standardized using results from a representative sample of the general population. The content validity of the AQoL-8D was assessed by comparing it with the dimension scores from the SF-36 and the summary component (physical and mental) scores. Overall scores from the SF-36 and AQoL-8D instruments were regressed upon patient BMI and the results from the AQoL-8D used to estimate the effect of overweight and obesity upon utility and lost QALYs.RESULTS: The comparison of the instruments indicated that the AQoL-8D has good convergent, concurrent and content validity. Using both instruments, obesity was significantly associated with lower scores for 14 of their 16 dimensions. AQoL-8D, in particular, identified a significant decrease in psychological and social health with happiness, self-worth, coping and mental health, all being poorer than in the control group. Regression results implied that a change in BMI from 30 to 50 decreases utility by 0.12 or by 13.8 percent of the average utility for a 25-35 year old.CONCLUSION: AQoL-8D is a valid measure of utility in the context of obesity. Its inclusion of psycho-social effects significantly increases the measured adverse effects of obesity.

Leisure Lifestyle and Health-Related Quality of Life of Taiwanese Adults

2012 ◽  
Vol 40 (2) ◽  
pp. 301-317 ◽  
Author(s):  
Ming-Ching Yang ◽  
Jen-Son Cheng ◽  
Shu-Wen Yu
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Health Related Quality ◽  
Short Form Health Survey ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Relationship ◽  
Short Form Health

The relationship between various leisure lifestyles (LLS) and health-related quality of life (HRQoL) was analyzed. The 36-Item Short-Form Health Survey (SF-36; Ware, Kosinski, & Keller, 1994) was completed by 622 residents of Taiwan. Factor analysis resulted in 6 dimensions of leisure lifestyle: preferred travel, self-realization, morning action, exercise loving, homebody, and social support. The scores for self-realization were the highest and the scores for morning action the lowest. Cluster analysis was applied to categorize the respondents into 4 leisure lifestyle groups: morning exercisers, traveling and social people, static recreation people, and active exercisers. In general, those groups of people for whom their LLS included more exercise had a better HRQoL.

FRAILTY IS ASSOCIATED WITH IMPAIRED QUALITY OF LIFE AND FALLS IN MIDDLE-AGED AND OLDER EUROPEAN MEN

2013 ◽  
pp. 1-7
Author(s):  
M.D.L. O’CONNELL ◽  
A. TAJAR ◽  
T.W. O’NEILL ◽  
S.A. ROBERTS ◽  
D.M. LEE ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cohort Study ◽  
Short Form ◽  
Cardiovascular Health Study ◽  
Health Related Quality ◽  
Middle Aged ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Objectives:Adapt a measure of frailty for use in a cohort study of European men and explorerelationships with age, health related quality of life and falls. Design:Longitudinal cohort study. Setting:8European centers. Participants:3047 men aged 40-79 participating in the European Male Ageing Study (EMAS).Measurements: Frailty was assessed using an adaptation of the Cardiovascular Health Study criteria. Healthrelated quality of life was evaluated using the Rand Short Form-36 (SF-36) questionnaire which comprises bothmental and physical component scores. Self reported falls in the preceding 12 months were recorded at 2-yearfollow-up. Results:78 men (2.6%) were classified as frail (≥3 criteria) and 821 (26.9%) as prefrail (1-2 criteria).The prevalence of frailty increased from 0.1% in men aged 40-49 up to 6.8% in men aged 70-79. Compared torobust men, both prefrail and frail men had lower health related quality of life. Frailty was more stronglyassociated with the physical than mental subscales of the SF-36. Frailty was associated with higher risk of fallsOR (95% CI) 2.92 (1.52, 5.59). Conclusions:Frailty, assessed by the EMAS criteria, increased in prevalencewith age and was related to poorer health related quality of life and higher risk of falls in middle-aged and olderEuropean men. These criteria may help to identify a vulnerable subset of older men.

scholarly journals Dance Fitness Classes Improve the Health-Related Quality of Life in Sedentary Women

2020 ◽  
Vol 17 (11) ◽  
pp. 3771 ◽  
Author(s):  
Yaira Barranco-Ruiz ◽  
Susana Paz-Viteri ◽  
Emilio Villa-González
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Control Group ◽  
Health Related Quality ◽  
Middle Aged ◽  
Post Intervention ◽  
Wide Range ◽  
Related Quality ◽  
Health Related

Introduction: This study aims to analyze the effect of two dance-focused and choreographic fitness classes on Health-Related Quality of Life (HRQoL) in sedentary worker women. Methods: 65 sedentary middle-aged worker women (38 ± 7.3 years old) completed a 16-week intervention randomly assigned to: (1) dance fitness group based on Zumba Fitness classes (DF group, n = 25)], (2) dance fitness + functional strength training group (DFFT group, n = 20), and (3) control group (n = 20). HRQoL was assessed by the 36-Item Short-Form Health-Survey (SF-36), which evaluates 8 dimensions of health [General Health (GH), Physical Functioning (PF), Social Functioning (SF), Physical Role (PR), Emotional Role (ER), Bodily Pain (BP), Vitality (V), and Mental Health (MH)] scored from 0 (worst) to 100 (best health status). Results: The control group statistically differed from both exercise groups in PF and PR, and from the DF group in SF and MH showing a lower score. No statistical differences were observed between exercise groups post-intervention, except in V. DF group showed increases in GH, PF, SF, V, PR, and MH post-intervention. Conclusions: A 16-week dance fitness intervention based on Zumba Fitness classes generates notable improvements in a wide range of HRQoL dimensions in sedentary middle-aged worker women, especially in V, PR and MH dimensions.

scholarly journals La misura della qualità di vita e dell’utilità in farmacoeconomia: strumenti e loro applicazioni in una rassegna di letteratura

2002 ◽  
Vol 3 (4) ◽  
pp. 241-252
Author(s):  
Ya-Ting Chan
Keyword(s):  
Quality Of Life ◽  
Economic Evaluation ◽  
Cost Utility ◽  
Economic Evaluations ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Cost ◽  
The Relationship

In a climate of economic scarcity, decisions about the allocation of healthcare resources need to be made explicit. An economic evaluation is able to identify and quantify the relationship between an input of resources and an output, hence to appreciate the efficiency of the project. One of the recent methodological approaches that has been used increasingly in health economic evaluations is the ‘cost-utility analysis’ (CUA). CUA considers benefits in utility terms and uses a unique index to assess them. We investigated the generic measurements of health related quality of life in the economic evaluation. Different instruments for evaluating quality of life and utility were categorized and briefly introduced. Literatures published in the journal “PharmacoEconomics” in 1997-2001 regarding quality of life and utility were reviewed. We were especially interested in the application of health profile SF-36 and utility measure EQ-5D. Selected articles were further analyzed and some issues concerning the methodologies of quality of life and utility are discussed.

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