scholarly journals Bilateral synchronous benign ovarian neoplasm: A rare occurrence

2017 ◽  
Vol 23 (1) ◽  
pp. 31
Author(s):  
I U Takai ◽  
U A Umar ◽  
H A Nggada ◽  
M Bukar ◽  
B M Audu
Keyword(s):  
Ovarian Neoplasm ◽  
Rare Occurrence ◽  
Benign Ovarian Neoplasm

scholarly journals Evaluating intraoperative cytology with histopathology diagnosis and its importance in ovarian tumors

2020 ◽  
Vol 10 (1) ◽  
pp. 1630-1634
Author(s):  
Karishma Malla Vaidya ◽  
Bigya Shrestha ◽  
Runa Jha ◽  
Binit Shrestha ◽  
Aasiya Rajbhandari ◽  
...  
Keyword(s):  
Predictive Value ◽  
Ovarian Neoplasms ◽  
Ovarian Neoplasm ◽  
Imprint Cytology ◽  
Frozen Sections ◽  
Intraoperative Diagnosis ◽  
Touch Imprint Cytology ◽  
Intraoperative Cytology ◽  
Benign Ovarian Neoplasm

Background: Touch/ imprint cytology has been utilized for intraoperative evaluations of tumors to complement frozen sections in order to reach diagnosis prior to histopathology diagnosis. The main aim of this study is to find role of touch imprint in determining histopathology diagnosis of ovarian neoplasm. Materials and Methods: All together one hundred three cases were evaluated using both touch/imprint and histopathology diagnosis. The histopathology diagnoses consisted of Benign (n=85), borderline (n=4), and malignant (n=12). Touch imprint cytology consists of Negative for malignancy (n=90), Positive for malignancy (n=11) and inadequate (n=2). Inadequate smear was excluded from the study. Results: Both touch / imprint cytology were able to diagnose benign and malignant ovarian neoplasm. Out of 103 cases, in cytology showed 89.1% patients were negative and 10.9% patients were positive. Histopathology shows 84.2% of benign ovarian neoplasm, 3.9% borderline neoplasm and 11.9% of malignant. Diagnostic accuracy of touch/ imprint was 99% with sensitivity 100% and specificity was 91.67%. Positive predictive value was 98.89% and negative predictive value was 100%. Conclusion: Touch/ imprint cytology examination is simple, rapid and useful test in evaluation of ovarian neoplasms. It plays very important role in preliminary intraoperative diagnosis of benign and malignant ovarian neoplasms. 

scholarly journals Signet Ring Stromal Cell Tumor: A Legitimate (Benign) Mimic of Krukenberg Tumor

2018 ◽  
Vol 142 (10) ◽  
pp. 1289-1291 ◽  
Author(s):  
Ryan DeCoste ◽  
Saul L. Offman
Keyword(s):  
Stromal Cells ◽  
Patient Management ◽  
Stromal Cell ◽  
Surgical Excision ◽  
Ovarian Neoplasm ◽  
Cell Tumor ◽  
Krukenberg Tumor ◽  
Signet Ring ◽  
Benign Ovarian Neoplasm ◽  
Age Range

Signet ring stromal cell tumor is a rare, benign ovarian neoplasm thought to arise from ovarian stromal cells. The pathophysiology of these tumors is poorly understood. They present in women in a wide age range, often with nonspecific symptoms including lower abdominal or pelvic pain. Their morphologic appearance raises a critical differential diagnosis of Krukenberg tumor, an aggressive malignancy with significant implications for patient management. For this reason, it is important for the pathologist to be aware of signet ring stromal cell tumor and its differentiating features, including useful histochemical and immunohistochemical ancillary tests. These tumors are curable with surgical excision, and there have been no recurrences or metastases among reported cases.

scholarly journals Circulating Exosomal miR-1290 for Diagnosis of Epithelial Ovarian Cancer

2022 ◽  
Vol 44 (1) ◽  
pp. 288-300
Author(s):  
Hyeji Jeon ◽  
Su Min Seo ◽  
Tae Wan Kim ◽  
Jaesung Ryu ◽  
Hyejeong Kong ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Target Gene ◽  
Molecular Mechanisms ◽  
Characteristic Curve ◽  
Ovarian Neoplasm ◽  
Cytokine Signaling ◽  
Formalin Fixed Paraffin ◽  
Formalin Fixed Paraffin Embedded ◽  
Benign Ovarian Neoplasm

The aim of the study was to develop a new diagnostic biomarker for identifying serum exosomal miRNAs specific to epithelial ovarian cancer (EOC) and to find out target gene of the miRNA for exploring the molecular mechanisms in EOC. A total of 84 cases of ovarian masses and sera were enrolled, comprising EOC (n = 71), benign ovarian neoplasms (n = 13). We detected expression of candidate miRNAs in the serum and tissue of both benign ovarian neoplasm group and EOC group using real-time polymerase chain reaction. Immunohistochemistry were constructed using formalin fixed paraffin embedded (FFPE) tissue to detect expression level of suppressor of cytokine signaling 4 (SOCS4). In the EOC group, miRNA-1290 was significantly overexpressed in serum exosomes and tissues as compared to benign ovarian neoplasm group (fold change ≥ 2, p < 0.05). We observed area under the receiver operating characteristic curve (AUC) for miR-1290, using a cut-off of 0.73, the exosomal miR-1290 from serum had AUC, sensitivity, and specificity values of 0.794, 69.2 and 87.3, respectively. In immunohistochemical study, expression of SOCS4 in EOC was lower than that in benign ovarian neoplasm. Serum exosomal miR-1290 could be considered as a biomarker for differential diagnosis of EOC from benign ovarian neoplasm and SOCS4 might be potential target gene of miR-1290 in EOC.

The Treatment of Patients Having Spontaneously Occurring Antibodies to Antihaemophilic Factor (Factor VIII)

1972 ◽  
Vol 28 (01) ◽  
pp. 120-128 ◽  
Author(s):  
C.R Rizza ◽  
J.O.P Edgcumbe ◽  
W.R Pitney ◽  
J.A Child
Keyword(s):  
Factor Viii ◽  
Rare Occurrence ◽  
Normal People

SummaryThe appearance of antibodies to factor VIII in the blood of previously normal people is a very rare occurrence but when it does happen the haemorrhagic condition which results can be very serious and difficult to treat.From experience of three cases described here it is recommended that treatment be witheld unless there is serious haemorrhage in which case steroids, large doses of cryoprecipitate or other human AHG should be given. In the case of life endangering haemorrhages it is justified to use the much more potent animal AHG preparations along with an immuno-suppressive drug.

Ruptured Cornual Ectopic Pregnancy – A Rare Occurrence

2012 ◽  
Vol 3 (3) ◽  
pp. 138-138
Author(s):  
Dahiya S Dahiya S ◽  
◽  
Premi H K Premi H K ◽  
Mukherjee S Mukherjee S
Keyword(s):  
Ectopic Pregnancy ◽  
Rare Occurrence

A Rare Case of Athelia in a Crossbred Cow

2017 ◽  
Vol 12 (3) ◽  
Author(s):  
R. Uma Rani
Keyword(s):  
Dairy Cattle ◽  
Congenital Anomalies ◽  
Rare Case ◽  
Congenital Abnormalities ◽  
Economic Value ◽  
Therapeutic Management ◽  
Rare Occurrence ◽  
Crossbred Cow

The udder is a very important organ and has economic value in dairy cattle. Though highly vulnerable to various disease conditions, e.g. mastitis, congenital anomalies in the udder are of rare occurrence (Dandale et al., 2013). Congenital abnormalities of the mammary system in cows comprise absence of teats, glands, supernumerary teats and imperforate teats. Absence of teat is extremely rare, but isolated cases in which the teats were only represented by slight eminences have been met with (O’ Connor, 1980). Athelia was reported in buffaloes by Sailendra and Sandhya (1998) and Vidyasagar (2009) and in a Japanese black heifer by Ghanem et al. (2011). In the present paper, a rare case of athelia in a Jersey crossbred cow and its therapeutic management by permanent cessation of lactation is reported.

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